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Hookworm Vaccine for Hookworm Infection
Study Summary
This trial is testing whether a hookworm vaccine is safe and effective. The study will infect participants with hookworms, then vaccinate them to see if the vaccine prevents infection.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Logistics
Participation is compensated
You will be compensated for participating in this trial.
Who is running the clinical trial?
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- I have a significant health condition like heart, lung, liver, kidney disease, diabetes, or an autoimmune disorder.I have severe asthma and use my inhaler daily or have been to the hospital for it in the last 6 months.I haven't taken corticosteroids or immunosuppressants in the last 30 days and don't plan to during the study.My kidney tests show abnormal results.I have had iron deficiency anemia in the past.I haven't received a live vaccine in the last 4 weeks or a killed vaccine in the last 2 weeks.I have not received any blood products in the last 6 months.I am between 18 and 45 years old.
- Group 1: 25 Necator americanus Hookworm Larvae
- Group 2: 50 Necator americanus Hookworm Larvae
- Group 3: 75 Necator americanus Hookworm Larvae
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What is the current scope of recruitment for this clinical trial?
"Affirmative. The information on clinicaltrials.gov implies that this medical trial is actively seeking to recruit participants. It was initially posted on 1/1/2015 and the most recent update occurred on 8/2/2022, with a total of 30 patients required for participation at one single site."
Are there still opportunities to participate in this investigation?
"Affirmative. Clinicaltrials.gov demonstrates that this clinical trial, which was originally posted on January 1st 2015, is actively recruiting participants. Approximately 30 patients must be recruited from a singular medical centre."
Is there a potential for harm when exposed to Necator americanus Hookworm Larvae?
"Our team at Power assigned Necator americanus Hookworm Larvae a score of 1 on the safety scale, as this is an early-phase trial with limited evidence supporting its use."
Does this trial include participants who are 35 years or older?
"Participants eligible for this trial must be between 18 and 45 years old. For those under the age of consent, there are 199 studies available, whereas older individuals can choose from 607 trials."
Who can partake in this trial and its associated benefits?
"This trial is open for enrolment of 30 individuals with bunostomiasis between the age limits of 18 to 45. The mandatory criteria are: male or female and aged between 18-45 years old, able to participate throughout the entire 6 months duration of this experiment."
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