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5-alpha-reductase inhibitor

Avodart vs. Proscar for Enlarged Prostate

Phase 4

Waitlist Available

Research Sponsored by Urologic Consultants of Southeastern PA

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

On finasteride for no less than 12 months

Age 50-80

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 12 months

Awards & highlights

Study Summary

This trial is testing whether a different medication, dutasteride, may be more effective than the current medication, finasteride, in decreasing prostate volume, improving symptoms, and reducing urine retention.

Who is the study for?

This trial is for men aged 50-80 with Benign Prostatic Hyperplasia (BPH) who have been on finasteride for at least a year. Participants must be willing to undergo all required tests over a 12-month period, including two blood draws and transrectal ultrasounds of the prostate (TRUSP). Men with a history of not taking medication as prescribed or unwillingness to tolerate these procedures cannot join.Check my eligibility

What is being tested?

The study is testing if Dutasteride is more effective than Finasteride in reducing prostate size and improving symptoms based on the International Prostate Symptom Score. It also looks at lowering post-void residual urine volume. The hypothesis suggests Dutasteride could be better because it blocks both types of an enzyme linked to BPH, compared to Finasteride's action on only one type.See study design

What are the potential side effects?

Potential side effects may include sexual dysfunction, such as decreased libido, erectile dysfunction, or ejaculation disorders; breast tenderness or enlargement; dizziness; and allergic reactions like rash, itching, hives, or swelling.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have been taking finasteride for at least 12 months.

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I am between 50 and 80 years old.

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I am male.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 12 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~12 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Laboratory parameters: including serum testosterone, DHT level and PSA

Secondary outcome measures

A decrease in the AUASI

volume measurements of TRUSP and PVR

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

Urologic Consultants of Southeastern PALead Sponsor

1 Previous Clinical Trials

52 Total Patients Enrolled

Media Library

Dutasteride (5-alpha-reductase inhibitor) Clinical Trial Eligibility Overview. Trial Name: NCT00690950 — Phase 4

Enlarged Prostate Research Study Groups:

Enlarged Prostate Clinical Trial 2023: Dutasteride Highlights & Side Effects. Trial Name: NCT00690950 — Phase 4

Dutasteride (5-alpha-reductase inhibitor) 2023 Treatment Timeline for Medical Study. Trial Name: NCT00690950 — Phase 4

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this treatment modality safe for patients to utilize?

"This treatment is approved and thus rated with a 3 on our safety scale, since it has completed Phase 4 of clinical trials."

Answered by AI

Are people who are over 20 eligible to participate in this investigation?

"To be admitted into this experiment, applicants must lie between the age boundary of 50 to 80. As an alternative, there are 28 trials tailored for minors and 105 studies aimed at seniors aged above 65."

Answered by AI

Could I potentially qualify for involvement in this clinical experiment?

"To be eligible for this trial, prospective participants must have a benign prostatic hyperplasia (bph) diagnosis and fall between the ages of 50 to 80. The recruitment process is looking for approximately 50 individuals."

Answered by AI

Is there room for additional participants in this clinical research?

"At present, clinicaltrials.gov reveals that this study is not in the process of enrolling patients. Posted on May 1st 2008 and last amended on June 4th 2008, no new participants are being solicited for this medical trial; however, 137 other trials remain open to recruitment."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

A Study to Determine the Improvement of the Symptoms of Benign Prostatic Hyperplasia (BPH) When Switching Subjects From Proscar to Avodart

2008. "A Study to Determine the Improvement of the Symptoms of Benign Prostatic Hyperplasia (BPH) When Switching Subjects From Proscar to Avodart". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00690950.

All > Benign Prostatic Hyperplasia > Bph