Bile Duct Cancer Clinical Trials
Here are the 6 most popular medical studies for bile duct cancer
Copper Cu 64 Anti-CEA Monoclonal Antibody M5A PET Scan for Cancer
This trial uses a radioactive antibody to help detect cancer cells in patients with high levels of a protein called CEA. PET scans may help find and diagnose cancer that may not be detected by other methods.
Radiotherapy
Radioembolization Treatment for Intrahepatic Cholangiocarcinoma
This trial is testing whether a type of ultrasound that uses gas microbubbles can predict how well bile duct cancer will respond to targeted radiotherapy. The ultrasound may also help doctors see if microbubble popping can improve bile duct cancer response to radiotherapy.
Popular filter options for bile duct cancer trials
Cholangiocarcinoma Clinical Trials
View 80 Cholangiocarcinoma medical studies.
Enzyme Inhibitor
BAY 1895344 + Chemotherapy for Bladder Cancer
This trial is testing a new drug, BAY 1895344, to see if it's effective and has minimal side effects when combined with chemotherapy to treat patients with advanced solid tumors or urothelial cancer.
EBD Cancer Clinical Trials
View 62 EBD Cancer medical studies.
Enzyme Inhibitor
BAY 1895344 + Chemotherapy for Bladder Cancer
This trial is testing a new drug, BAY 1895344, to see if it's effective and has minimal side effects when combined with chemotherapy to treat patients with advanced solid tumors or urothelial cancer.
Metastatic Bile Duct Cancer Clinical Trials
View 98 metastatic bile duct cancer medical studies.
Enzyme Inhibitor
BAY 1895344 + Chemotherapy for Bladder Cancer
This trial is testing a new drug, BAY 1895344, to see if it's effective and has minimal side effects when combined with chemotherapy to treat patients with advanced solid tumors or urothelial cancer.
FGFR2 Positive Clinical Trials
View 8 FGFR2 positive medical studies.
Kinase Inhibitor
Pemigatinib vs Chemotherapy for Bile Duct Cancer
This trial will compare the effectiveness of pemigatinib versus gemcitabine plus cisplatin chemotherapy as first-line treatment for people with cholangiocarcinoma that cannot be removed by surgery or has spread to other parts of the body.
IDH1 Inhibitor
Chemotherapy + Targeted Therapy for Bile Duct Cancer
This trial is testing the side effects and best dose of two chemotherapy drugs, gemcitabine and cisplatin, when given with either of two targeted drugs, ivosidenib or pemigatinib, in treating patients with cholangiocarcinoma that cannot be removed with surgery or has spread to other places in the body.
IDH Positive Clinical Trials
View 7 IDH positive medical studies.
PARP Inhibitor
Olaparib for Advanced Cancer
This trial will study how well olaparib works in treating patients with certain types of cancer that have spread and usually cannot be controlled with treatment. Olaparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
IDH1 Inhibitor
Chemotherapy + Targeted Therapy for Bile Duct Cancer
This trial is testing the side effects and best dose of two chemotherapy drugs, gemcitabine and cisplatin, when given with either of two targeted drugs, ivosidenib or pemigatinib, in treating patients with cholangiocarcinoma that cannot be removed with surgery or has spread to other places in the body.
Phase 3 Bile Duct Cancer Clinical Trials
View 98 phase 3 bile duct cancer medical studies.
Kinase Inhibitor
Pemigatinib vs Chemotherapy for Bile Duct Cancer
This trial will compare the effectiveness of pemigatinib versus gemcitabine plus cisplatin chemotherapy as first-line treatment for people with cholangiocarcinoma that cannot be removed by surgery or has spread to other parts of the body.
Bile Duct Cancer Clinical Trials With No Placebo
View 98 bile duct cancer medical studies that do not have a placebo group.
Enzyme Inhibitor
BAY 1895344 + Chemotherapy for Bladder Cancer
This trial is testing a new drug, BAY 1895344, to see if it's effective and has minimal side effects when combined with chemotherapy to treat patients with advanced solid tumors or urothelial cancer.
View More Bile Duct Cancer Trials
See another 71 medical studies focused on bile duct cancer.
Frequently Asked Questions
Introduction to bile duct cancer
What are the top hospitals conducting bile duct cancer research?
When it comes to the battle against bile duct cancer, several top hospitals are leading the charge in clinical trials. In New york City, Memorial Sloan Kettering Cancer Center stands out with five active trials dedicated to this rare and challenging disease. With a history of eight completed studies since their first recorded trial in 2000, they have been at the forefront of research for over two decades. Meanwhile, all the way in Bethesda, Maryland, the National Institutes of Health Clinical Center is also making significant strides. They currently have four active clinical trials for bile duct cancer and have been conducting these studies since 2013.
Similarly contributing to this vital research is the University of California Davis Comprehensive Cancer Center in Sacramento. With four ongoing trials focusing on bile duct cancer and a total of five completed studies dating back to their inaugural investigation in 2010, they are making an impact on understanding this complex condition.
In Columbus, Ohio State University Comprehensive Cancer Center has joined forces as well with its own set of four active clinical trials for bile duct cancer and a consistent dedication demonstrated through their previous five investigations that commenced from 2011 onwards.
Last but not least among these pioneering institutions is the City of Hope Comprehensive Cancer Center located in Duarte. This esteemed center has displayed unwavering commitment by conducting three previous bile duct cancer trials since recording their first study on this specific type of cancer back in 2014; additionally demonstrating equal dedication towards finding new treatment possibilities through participating actively within same number -four- present-day tests focused solely upon such cases.
These remarkable efforts across multiple medical centers symbolize hope for those affected by bile duct cancer while emphasizing how collaboration among experts can lead to advancements in treatment options and improved outcomes for patients globally.
Which are the best cities for bile duct cancer clinical trials?
When it comes to bile duct cancer clinical trials, several cities show promise in advancing research and treatment options. Honolulu, Hawaii, leads the way with 23 active trials investigating treatments like Arm B (pevonedistat, paclitaxel, carboplatin), Cisplatin, and DB-1303. Anchorage, Alaska follows closely behind with 16 ongoing studies focusing on Cisplatin and alternative therapies. Boston, Massachusetts also plays a significant role with 12 active trials exploring Cobimetinib, pembrolizumab, DB-1303 among others. Lastly,'Aiea in Hawaii and Houston,Texas showcase their commitment to breakthroughs by hosting eight active trials each that investigate various treatment strategies for bile duct cancer patients. These cities serve as crucial hubs for cutting-edge clinical research aiming to improve outcomes for individuals fighting this challenging disease.
Which are the top treatments for bile duct cancer being explored in clinical trials?
Clinical trials investigating potential treatments for bile duct cancer have yielded several promising options. Topping the list is tivozanib, a newcomer with two active trials and a total of two all-time studies focusing on bile duct cancer since its first listing in 2021. Cisplatin follows closely behind, also engaged in two ongoing trials and contributing to nine all-time research endeavors since being listed in 2007. Nab-paclitaxel shows similar promise with two active trials and an equal number of all-time studies dedicated to examining its efficacy against bile duct cancer after it was listed as a treatment option in 2019. Lastly, floxuridine enters the scene with one active trial and one all-time study specifically targeting bile duct cancer since its inclusion as a potential therapy began in 2022. These clinical investigations offer hope for improved outcomes for individuals battling this challenging form of cancer.
What are the most recent clinical trials for bile duct cancer?
Recent clinical trials have offered new possibilities for patients with bile duct cancer, presenting potential advancements in treatment options. One such trial is Arm A, a Phase 2 study that explores an innovative approach to tackling this type of cancer. Additionally, the combination of Gemcitabine + Cisplatin + Durvalumab + Yttrium-90 Selective Internal Radiation Therapy has shown promise as a potential therapy option in Phase 2 trials. Another Phase 2 trial investigated the efficacy of Floxuridine specifically for bile duct cancer patients. Furthermore, Nab-paclitaxel and Tivozanib have been under investigation in both Phase 1 and Phase 2 studies as potential treatments for bile duct cancer. These recent clinical trials bring renewed hope to those affected by this challenging disease.
What bile duct cancer clinical trials were recently completed?
Several clinical trials investigating potential treatments for bile duct cancer have recently concluded, offering valuable insights into the battle against this challenging disease. In October 2019, Mayo Clinic successfully completed a trial evaluating the efficacy of Trifluridine and Tipiracil Hydrochloride in combating bile duct cancer. Another notable study was conducted by Klus Pharma Inc., completing in July 2018, exploring the effectiveness of A166 therapy. Additionally, Intensity Therapeutics, Inc.'s research on INT230-6 reached completion in February 2017. These milestones highlight the commitment of researchers to finding innovative solutions for bile duct cancer patients and underline the ongoing efforts to improve treatment options for this condition.