Radiation Therapy for Liver Cancer

Phase-Based Progress Estimates
M D Anderson Cancer Center, Houston, TXLiver Cancer+3 MoreRadiation Therapy - Radiation
All Sexes
What conditions do you have?

Study Summary

This trial studies the side effects and best dose of radiation therapy in treating patients with liver cancer that has spread or caused liver damage.

Eligible Conditions
  • Liver Cancer
  • Bile Duct Cancer
  • Liver Cirrhosis

Treatment Effectiveness

Study Objectives

1 Primary · 4 Secondary · Reporting Duration: Up to 2 years

Week 8
Maximum dose constraint
Tumor biomarker expression in serum
Up to 2 years
Local disease control rate
Overall survival
Patterns of failure
Tumor response

Trial Safety

Trial Design

1 Treatment Group

Treatment (radiation therapy)
1 of 1

Experimental Treatment

88 Total Participants · 1 Treatment Group

Primary Treatment: Radiation Therapy · No Placebo Group · Phase 1

Treatment (radiation therapy)Experimental Group · 4 Interventions: Laboratory Biomarker Analysis, Magnetic Resonance Imaging, Survey Administration, Radiation Therapy · Intervention Types: Other, Procedure, Other, Radiation
First Studied
Drug Approval Stage
How many patients have taken this drug
Magnetic Resonance Imaging
Completed Phase 3
Radiation Therapy
Completed Phase 3

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: up to 2 years

Who is running the clinical trial?

M.D. Anderson Cancer CenterLead Sponsor
2,827 Previous Clinical Trials
1,792,759 Total Patients Enrolled
22 Trials studying Liver Cancer
7,569 Patients Enrolled for Liver Cancer
National Cancer Institute (NCI)NIH
13,153 Previous Clinical Trials
41,162,220 Total Patients Enrolled
103 Trials studying Liver Cancer
21,268 Patients Enrolled for Liver Cancer
Eugene J KoayPrincipal InvestigatorM.D. Anderson Cancer Center
5 Previous Clinical Trials
294 Total Patients Enrolled

Eligibility Criteria

Age 18+ · All Participants · 14 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are expected to live for at least 3 more months.
Your doctor may decide to give you capecitabine or sorafenib alongside the study treatment.
You can have one or more tumors.
It is okay if you have previously had surgery, chemotherapy, transarterial chemoembolization (TACE), and/or radiofrequency ablation.
Your tumor size does not matter, but the radiation treatment plan must follow specific rules to ensure safety.

Frequently Asked Questions

How many subjects are included in the current research?

"Affirmative. The information available on clinicaltrials.gov reveals that recruitment is ongoing for this research endeavour, which was first posted in February 15th 2016 and last edited June 16th 2021. 88 participants will be accepted from 1 site to take part in the trial." - Anonymous Online Contributor

Unverified Answer

Has Radiotherapy been validated by the FDA?

"Due to limited data on its efficacy and safety, Radiation Therapy earned a score of 1." - Anonymous Online Contributor

Unverified Answer

Are there any patients being enrolled in this research endeavor at present?

"Affirmative, the data shared on clinicaltrials.gov verifies that this medical trial is actively enrolling members. The study was initially posted February 15th 2016 and last modified June 16 2021. A total of 88 patients are needed from one centre." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.