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Radiation Therapy for Liver Cancer
Study Summary
This trial studies the side effects and best dose of radiation therapy in treating patients with liver cancer that has spread or caused liver damage.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I had liver radiation therapy over 6 months ago for Y90 or over 12 months for others.I have one or more tumors.I may be taking capecitabine or sorafenib as part of my treatment.I have had surgery, chemotherapy, TACE, or radiofrequency ablation before.I can become pregnant and agree to use birth control and not breastfeed.I currently have a fever or an untreated infection.I do not have active hepatitis.My inflammatory bowel disease is not well-managed.I have been cancer-free for at least 3 years, except for non-melanoma skin cancer or early prostate cancer with stable PSA levels.My cancer treatment plan meets the required radiation dose limits.I have mild liver cirrhosis with enough healthy liver tissue.I have had radiation therapy targeted at my liver.My liver is not working well due to advanced cirrhosis.I have had liver surgery or certain chemotherapies but still have at least 400 ml of healthy liver.My liver function score is over 6, and I've had liver radiation.My liver function score is either below 6 or above 9, and I haven't had radiation before.You are expected to live for at least 3 more months.I haven't had a severe heart condition or heart attack in the last 6 months.I have been diagnosed with liver cancer or liver metastasis.I've had liver surgery, chemotherapy with irinotecan or oxaliplatin, and at least 400 ml of healthy liver.I can take care of myself and am up and about more than half of the day.I have had yttrium-90 therapy before.I am currently pregnant.
- Group 1: Treatment (radiation therapy)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How many subjects are included in the current research?
"Affirmative. The information available on clinicaltrials.gov reveals that recruitment is ongoing for this research endeavour, which was first posted in February 15th 2016 and last edited June 16th 2021. 88 participants will be accepted from 1 site to take part in the trial."
Has Radiotherapy been validated by the FDA?
"Due to limited data on its efficacy and safety, Radiation Therapy earned a score of 1."
Are there any patients being enrolled in this research endeavor at present?
"Affirmative, the data shared on clinicaltrials.gov verifies that this medical trial is actively enrolling members. The study was initially posted February 15th 2016 and last modified June 16 2021. A total of 88 patients are needed from one centre."
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