Reflux Band for Acid Reflux
Trial Summary
Do I have to stop taking my current medications for the trial?
The trial does not specify if you need to stop taking your current medications. However, it requires participants to be on a double daily dose acid suppression therapy, so you may need to continue those medications.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop your current medications, but it requires participants to be on a double daily dose of acid suppression therapy. It seems likely you will continue your current acid reflux medications during the trial.
What data supports the idea that Reflux Band for Acid Reflux is an effective treatment?
The available research does not provide specific data on the effectiveness of the Reflux Band for Acid Reflux. Instead, it focuses on various drugs like rabeprazole and pantoprazole, which are shown to be effective in relieving symptoms and healing damage caused by acid reflux. These drugs are compared to other treatments, such as H2-receptor antagonists, which are less effective in severe cases. However, there is no direct comparison or data on the Reflux Band in the provided information.12345
What safety data exists for the Reflux Band treatment for acid reflux?
The provided research does not contain specific safety data for the Reflux Band or Reza Band treatment for acid reflux. The studies focus on severe cutaneous adverse reactions to drugs and do not mention the Reflux Band or similar devices. Therefore, no relevant safety data for this treatment is available in the provided research.678910
Is the Reflux Band a promising treatment for acid reflux?
The provided research articles do not mention the Reflux Band or Reza Band as a treatment for acid reflux. They focus on various drugs and therapies for gastroesophageal reflux disease (GERD), such as vonoprazan, lesogaberan, and AZD0865, which are different from the Reflux Band. Therefore, based on the given information, we cannot determine if the Reflux Band is a promising treatment for acid reflux.511121314
How is the Reflux Band treatment different from other acid reflux treatments?
What is the purpose of this trial?
This trial tests if a special neck band can help people with throat issues caused by stomach acid. The band is worn at night and works by increasing pressure on a muscle to stop acid from reaching the throat.
Research Team
Rena Yadlapati, MD, MSHS
Principal Investigator
UC San Diego Health
Eligibility Criteria
This trial is for adults aged 18-99 with laryngopharyngeal reflux confirmed by tests, who have been on double dose acid suppression therapy. They must not have had neck cancer/surgery, use certain night-time breathing aids, or have specific conditions like glaucoma or a history of foregut surgery. Pregnant/breastfeeding individuals and those unable to consent in English/Spanish are excluded.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either the Reflux Band or a sham device for 8 weeks, wearing it nightly while sleeping
Unblinded Period
Participants continue using the device in an unblinded manner for 4 weeks
Optional Extension
Participants may opt into a 4-week extension where the Reflux Band is refit to provide the manufacturer's specified pressure
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Reflux Band
Reflux Band is already approved in United States, European Union for the following indications:
- Laryngopharyngeal reflux (LPR) disease
- Laryngopharyngeal reflux (LPR) disease
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of California, San Diego
Lead Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator