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Electrical Stimulation

Brain Stimulation for Epilepsy

N/A

Waitlist Available

Led By Barbara C Jobst, MD

Research Sponsored by Barbara Jobst

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

18 years of age or older

Diagnosis of epilepsy

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 30 days

Awards & highlights

Study Summary

This trial is testing a device that stimulates the brain to see if it improves memory in people with epilepsy.

Who is the study for?

This trial is for adults over 18 with epilepsy who have had an RNS® device implanted for at least 3 months. Participants must be able to consent and complete tasks as judged by the lead researcher.Check my eligibility

What is being tested?

The study examines how brain activity linked to good memory functions in people with epilepsy using ECoG data from those with an RNS® device during memory and navigation tasks.See study design

What are the potential side effects?

While not explicitly stated, potential side effects may include discomfort or changes in seizure patterns due to electrical stimulation, as well as typical risks associated with ECoG data collection.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am 18 years old or older.

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I have been diagnosed with epilepsy.

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I have an RNS device for my epilepsy.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 30 days

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~30 days

This trial's timeline: 3 weeks for screening, Varies for treatment, and 30 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Proportion of words recalled with and without stimulation.

Secondary outcome measures

Changes in the power spectrum of ECoG data with an increase of recalled words.

Proportion of navigation challenges recalled successfully with and without stimulation.

Proportion of words recalled during times of interictal activity.

Trial Design

1Treatment groups

Experimental Treatment

Group I: RNS® NeurostimulatorExperimental Treatment1 Intervention

Subjects with pharmaceutically intractable seizures who have been implanted with a RNS® Neurostimulator.

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

Barbara JobstLead Sponsor

NeuroPaceIndustry Sponsor

10 Previous Clinical Trials

1,475 Total Patients Enrolled

8 Trials studying Epilepsy

1,389 Patients Enrolled for Epilepsy

Barbara C Jobst, MDPrincipal InvestigatorDartmouth-Hitchcock Medical Center

2 Previous Clinical Trials

116 Total Patients Enrolled

2 Trials studying Epilepsy

116 Patients Enrolled for Epilepsy

Media Library

Electrical Stimulation (Electrical Stimulation) Clinical Trial Eligibility Overview. Trial Name: NCT02781129 — N/A

Epilepsy Research Study Groups: RNS® Neurostimulator

Epilepsy Clinical Trial 2023: Electrical Stimulation Highlights & Side Effects. Trial Name: NCT02781129 — N/A

Electrical Stimulation (Electrical Stimulation) 2023 Treatment Timeline for Medical Study. Trial Name: NCT02781129 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are additional participants being recruited for this clinical research study?

"As corroborated on clinicaltrials.gov, this research project is not presently recruiting participants. The trial was first posted in May 2016 and last updated June 3rd 2022; however, as an alternative, there are 238 other studies that have open enrollment currently."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Navigation and Free Recall in Chronically Implanted Humans

Barbara Jobst 2016. "Navigation and Free Recall in Chronically Implanted Humans". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02781129.

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