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Speech-motor behavioral testing

N/A
Recruiting
Led By Richard Ivry, Ph.D.
Research Sponsored by University of California, San Francisco
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Diagnosis of cerebellar ataxia (CA) resulting from degeneration of the cerebellum AND normal hearing abilities OR Healthy volunteers with no known history of physical or neurological abnormalities AND normal speech, hearing, and reading abilities
Be older than 18 years old
Timeline
Screening 1 day
Treatment Varies
Follow Up 3 days
Awards & highlights

Study Summary

This trial will investigate how the cerebellum is involved in speech motor learning and short-term corrections in patients with cerebellar ataxia and healthy controls.

Eligible Conditions
  • Cerebellar Ataxia
  • Dysarthria
  • Healthy Subjects

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
You have a condition called cerebellar ataxia that affects your balance and coordination and you have no hearing problems, OR you are a healthy person with no history of physical or neurological problems and have normal speech, hearing, and reading abilities.

Timeline

Screening ~ 1 day
Treatment ~ Varies
Follow Up ~3 days
This trial's timeline: 1 day for screening, Varies for treatment, and 3 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Dysarthria symptoms
Speech
Voxel-based morphometry (VBM)

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Patients with cerebellar ataxia (CA)Experimental Treatment2 Interventions
Behavioral testing including various speaking tasks Magnetic resonance imaging (MRI)
Group II: Additional healthy volunteersExperimental Treatment3 Interventions
Behavioral testing including various speaking tasks Magnetic resonance imaging (MRI) Transcranial magnetic stimulation (TMS)
Group III: Matched controlsActive Control2 Interventions
Behavioral testing including various speaking tasks Magnetic resonance imaging (MRI)
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
TMS
2021
Completed Phase 2
~2170
MRI
2009
Completed Phase 2
~1370

Find a Location

Logistics

Other reimbursement is provided

Other forms of reimbursement are provided for this trial.

Who is running the clinical trial?

National Institute on Deafness and Other Communication Disorders (NIDCD)NIH
324 Previous Clinical Trials
177,854 Total Patients Enrolled
University of Wisconsin, MadisonOTHER
1,176 Previous Clinical Trials
3,011,687 Total Patients Enrolled
University of California, San FranciscoLead Sponsor
2,491 Previous Clinical Trials
11,930,316 Total Patients Enrolled
1 Trials studying Cerebellar Ataxia
200 Patients Enrolled for Cerebellar Ataxia

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this clinical research program open to participants over the age of 35?

"In accordance with the requirements for this clinical examination, participants must be aged 18 to 75 years old."

Answered by AI

How many participants is the research team recruiting for their experiment?

"Absolutely. According to the details posted on clinicaltrials.gov, this medical trial is currently accepting participants; it was initially published on September 15th 2019 and recently updated on October 10th 2022. A total of 264 individuals are required to partake in the study across 3 separate centres."

Answered by AI

Is participation in this investigation available to interested parties?

"The records on clinicaltrials.gov indicate that the trial is recruiting participants; it was initially posted in September 15th 2019 and underwent its latest alteration October 10th 2022."

Answered by AI

Are there any criteria for participation in this experiment?

"This clinical trial seeks 264 individuals suffering from dysarthria, aged 18-75 years old."

Answered by AI

Who else is applying?

What state do they live in?
Wisconsin
California
What site did they apply to?
University of California, San Francisco
University of Wisconsin--Madison
University of California, Berkeley
What portion of applicants met pre-screening criteria?
Did not meet criteria
Met criteria
How many prior treatments have patients received?
0

Why did patients apply to this trial?

Healthy subject looking for a paid study and to help out with medical research!
PatientReceived 2+ prior treatments

How responsive is this trial?

Average response time
  • < 2 Days
Typically responds via
Email
Most responsive sites:
  1. University of California, Berkeley: < 48 hours
Recent research and studies
~48 spots leftby Mar 2025