Transcranial Magnetic Stimulation for Healthy Subjects
Trial Summary
Will I have to stop taking my current medications?
If you are currently taking psychoactive medication, you cannot participate in this trial. The protocol does not specify about other medications, but it seems you should not be on any medications that could affect brain activity.
What data supports the effectiveness of the treatment Transcranial Magnetic Stimulation for healthy subjects?
Is repetitive transcranial magnetic stimulation (rTMS) safe for healthy individuals?
How is transcranial magnetic stimulation different from other treatments?
Transcranial magnetic stimulation (TMS) is unique because it is a non-invasive and painless method that uses magnetic fields to stimulate specific areas of the brain. Unlike medications, TMS directly targets brain regions to modulate their activity, which can be beneficial for conditions like depression and cognitive processing without the systemic side effects of drugs.211121314
What is the purpose of this trial?
The project examines electroencephalography, MRI, and behavioral measures indexing flexibility (critical state dynamics) in the brain when healthy young adults do demanding cognitive tasks, and in response to transcranial magnetic stimulation.
Research Team
John A Westbrook, PhD
Principal Investigator
Rutgers University
Eligibility Criteria
This trial is for healthy, neurologically normal adults aged 18-45 who speak English fluently and have at least a high school education. Participants must have normal vision or corrected-to-normal vision, be willing to follow the MRI and stimulation protocol, and commit to the study duration.Inclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Theta-burst Stimulation
Participants receive either sham, continuous, or intermittent theta-burst stimulation to the right frontal eye field in a cross-over design
Cognitive Task Performance
Participants perform control-demanding cognitive tasks to assess the effects of stimulation on cognitive control and subjective effort
Follow-up
Participants are monitored for safety and effectiveness after stimulation
Treatment Details
Interventions
- Transcranial Magnetic Stimulation
Find a Clinic Near You
Who Is Running the Clinical Trial?
Rutgers, The State University of New Jersey
Lead Sponsor