Behavioral Activation Therapy for Depression

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Depression+1 MoreBehavioral Activation Therapy - Behavioral
Eligibility
18+
All Sexes
What conditions do you have?
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Study Summary

This trial may help pregnant smokers who are depressed quit smoking and stay smoke-free after their babies are born.

Eligible Conditions
  • Depression
  • Tobacco Use Disorder

Treatment Effectiveness

Study Objectives

1 Primary · 0 Secondary · Reporting Duration: Up to 6 months postpartum

Month 6
Focus group

Trial Safety

Trial Design

5 Treatment Groups

Aim 3 Group I (BA)
1 of 5
Aim 1 and secondary aim 2 (focus group)
1 of 5
Aim 4 Group IV (HW)
1 of 5
Aim 4 Group III (BA)
1 of 5
Aim 3 Group II (HW)
1 of 5

Experimental Treatment

99 Total Participants · 5 Treatment Groups

Primary Treatment: Behavioral Activation Therapy · No Placebo Group · N/A

Aim 3 Group I (BA)Experimental Group · 2 Interventions: Behavioral Activation Therapy, Tobacco Cessation Counseling · Intervention Types: Behavioral, Other
Aim 1 and secondary aim 2 (focus group)
Procedure
Experimental Group · 1 Intervention: Discussion · Intervention Types: Procedure
Aim 4 Group IV (HW)Experimental Group · 3 Interventions: Health Education, Questionnaire Administration, Tobacco Cessation Counseling · Intervention Types: Behavioral, Other, Other
Aim 4 Group III (BA)Experimental Group · 3 Interventions: Questionnaire Administration, Behavioral Activation Therapy, Tobacco Cessation Counseling · Intervention Types: Other, Behavioral, Other
Aim 3 Group II (HW)Experimental Group · 2 Interventions: Health Education, Tobacco Cessation Counseling · Intervention Types: Behavioral, Other
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Health Education
2014
Completed Phase 3
~4000
Discussion
2018
N/A
~100
Behavioral Activation Therapy
2018
Completed Phase 4
~700

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: up to 6 months postpartum

Who is running the clinical trial?

M.D. Anderson Cancer CenterLead Sponsor
2,807 Previous Clinical Trials
1,790,352 Total Patients Enrolled
10 Trials studying Depression
701,351 Patients Enrolled for Depression
Jan BlalockPrincipal InvestigatorM.D. Anderson Cancer Center
1 Previous Clinical Trials
54,158 Total Patients Enrolled
Jan Blalock, MDPrincipal InvestigatorM.D. Anderson Cancer Center

Eligibility Criteria

Age 18+ · All Participants · 7 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You must have a telephone.\n
You have smoked, even a puff, cigarettes, little cigars or cigarillos in the past 30 days.
You are able to speak and read English.\n