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Cannabinoid

Cannabinoids for Memory Function (THC-Memory Trial)

Phase 1
Waitlist Available
Led By Mohini Ranganathan, M.D.
Research Sponsored by Yale University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Men and women aged 18 and 55 years (extremes included) on day of first dosing
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up +35 minutes after infusion
Awards & highlights

THC-Memory Trial Summary

This trial will study how different cannabinoids affect working and episodic memory.

Who is the study for?
This trial is for men and women aged between 18 and 55 who have used cannabis at least once. It's not suitable for those with hearing deficits, individuals who've never used cannabis, or women with a positive pregnancy test.Check my eligibility
What is being tested?
The study aims to understand how cannabinoids affect memory by comparing the effects of THC (a compound found in cannabis) against a placebo in learning and memory tasks.See study design
What are the potential side effects?
While the document doesn't specify side effects, THC can typically cause changes in mood, altered senses, impaired body movement, difficulty thinking or problem-solving, and sometimes hallucinations.

THC-Memory Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 18 and 55 years old.

THC-Memory Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~+35 minutes after infusion
This trial's timeline: 3 weeks for screening, Varies for treatment, and +35 minutes after infusion for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
N-Back Task
Rey Auditory Verbal Learning Test (RAVLT)
Secondary outcome measures
Clinician Administered Dissociative Symptoms Scale (Total Score)
Visual Analog Scale (Total Score)

THC-Memory Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: THCActive Control2 Interventions
Active THC (0.0015mg/kg-0.03mg/kg) administered over 20 minutes.
Group II: PlaceboPlacebo Group2 Interventions
Control: small amount of alcohol intravenously (quarter teaspoon), with no THC over 20 minutes.

Find a Location

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

Yale UniversityLead Sponsor
1,847 Previous Clinical Trials
2,736,448 Total Patients Enrolled
14 Trials studying Cannabis
744 Patients Enrolled for Cannabis
Mohini Ranganathan, M.D.Principal Investigator - Assistant Professor
Yale University
4 Previous Clinical Trials
184 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

To whom does this research opportunity extend?

"This research is recruiting 80 individuals with a history of psychosis between 18 and 55 years old. The primary requirements are that they have experimented with cannabis before, and fall into the specified age range on the day of initial dosing."

Answered by AI

Are there any adverse effects associated with THC ingestion?

"The team at Power has assigned THC a rating of 1 on their safety scale, as this is an early-stage trial with scant evidence backing its efficacy and minimal proof of safety."

Answered by AI

Are persons aged 50 or older permitted to participate in this research?

"This trial is only open to individuals aged 18-55. However, there are numerous medical studies available for younger and older patients - 114 trials that accept under 18s and 275 experiments targeting those over 65 years old."

Answered by AI

Is this medical experiment open to new participants?

"Unfortunately, clinicaltrials.gov shows that this particular medical trial is not currently recruiting any participants. The study was initially posted in February 2015 and recently modified on July 28th 2022; however, 456 other studies are actively searching for individuals to join their trials at the moment."

Answered by AI

Who else is applying?

What portion of applicants met pre-screening criteria?
Met criteria
What site did they apply to?
VA Connecticut Healthcare System
Recent research and studies
clinicaltrials.govStudy
Cannabinoids, Learning, and Memory
Mohini Ranganathan 2015. "Cannabinoids, Learning, and Memory". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02407808.
All > Memory > Paid Studies Connecticut
~8 spots leftby Apr 2025
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