Transcranial Magnetic Stimulation for Scrotal Pain
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores whether Transcranial Magnetic Stimulation (TMS), a non-invasive treatment using magnetic fields, can reduce chronic scrotal pain. The aim is to determine if TMS is a feasible method for managing pain that persists for at least six months. Men experiencing scrotal pain at least three days a week may be suitable candidates for this study. Participants should not have started any new pain medications in the past 30 days. As a Phase 1 trial, the research focuses on understanding how the treatment works in people, offering participants the opportunity to be among the first to receive this innovative treatment.
Do I need to stop my current medications for the trial?
The trial does not specify if you need to stop your current medications, but you cannot have started any new pain medications in the last 30 days.
What prior data suggests that Transcranial Magnetic Stimulation is safe for treating scrotal pain?
Research has shown that transcranial magnetic stimulation (TMS) is generally safe and easy to manage. Studies have found that side effects are usually mild and short-lived. Most people may experience temporary discomfort or pain on the scalp where the device contacts the skin. In one study, only a small number of participants (4.5%) discontinued treatment due to these side effects. This suggests that TMS is manageable for most individuals. Overall, TMS appears to be a low-risk option for treating conditions like chronic scrotal pain.12345
Why do researchers think this study treatment might be promising?
Transcranial Magnetic Stimulation (TMS) is unique because it offers a non-invasive approach to treating scrotal pain, unlike the standard options, which often involve medications or surgical interventions. TMS works by using magnetic fields to stimulate nerve cells in the brain, potentially altering pain perception and providing relief without the side effects associated with pain medications. Researchers are excited about TMS because it represents a novel mechanism of action and could offer a safer, more effective alternative for those suffering from chronic scrotal pain.
What evidence suggests that Transcranial Magnetic Stimulation is effective for scrotal pain?
Research has shown that Transcranial Magnetic Stimulation (TMS) can help reduce pain. One study found that 14 patients experienced less pain after 10 sessions of repetitive TMS. This technique uses magnetic fields to stimulate nerve cells in the brain, altering pain perception. Although TMS is often used for other types of chronic pain, its application for scrotal pain remains under investigation. In this trial, participants will receive TMS to assess its effectiveness for scrotal pain. Early results suggest it might be helpful, but further research is needed to confirm its efficacy for this specific type of pain.26789
Who Is on the Research Team?
Jeffery Brockardt, Ph.D.
Principal Investigator
Medical University of South Carolina
Are You a Good Fit for This Trial?
This trial is for men who have had scrotal pain at least 3 days a week, ongoing for more than 6 months. Participants should not have started any new pain medications in the last 30 days.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
TMS is delivered using the MagVenture TMS machine, 15 minutes per session, 3 sessions each day, for 3 days
Follow-up
Participants are monitored for safety and effectiveness after treatment using a custom developed SMS text EMA system
What Are the Treatments Tested in This Trial?
Interventions
- Transcranial Magnetic Stimulation
Find a Clinic Near You
Who Is Running the Clinical Trial?
Medical University of South Carolina
Lead Sponsor