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CPAP Devices for Breast and Lung Cancer

N/A

Recruiting

Led By Chirag Shah, MD

Research Sponsored by Case Comprehensive Cancer Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Patients must be undergoing left breast/chest wall radiation with or without regional nodal irradiation

Patients with left-sided breast cancers

Timeline

Screening 3 weeks

Treatment Varies

Follow Up at the time of scan, " day 1"

Awards & highlights

Study Summary

This trial is testing whether using a CPAP device can help improve outcomes for patients with left-sided breast cancer or lung SBRT.

Who is the study for?

This trial is for patients with left-sided breast cancer or those undergoing lung SBRT, including cases of metastatic and primary lung cancers. It's not suitable for individuals with right-side breast cancer or those who cannot tolerate a CPAP device.Check my eligibility

What is being tested?

The study is evaluating the use of CPAP devices during radiation therapy to see if they can reduce the amount of radiation received by the lungs in patients with certain types of breast and lung cancers.See study design

What are the potential side effects?

While this trial focuses on data collection rather than drug effects, using a CPAP device may cause discomfort, difficulty sleeping, dry mouth or nose, and possible skin irritation where the mask contacts the face.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am receiving radiation therapy on my left breast or chest wall, possibly including nearby lymph nodes.

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My breast cancer is in the left breast.

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I am receiving targeted radiation therapy for my lung.

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My cancer has spread to my lungs.

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My cancer originated in my lungs.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ at the time of scan, " day 1"

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~at the time of scan, " day 1"

This trial's timeline: 3 weeks for screening, Varies for treatment, and at the time of scan, " day 1" for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Dosimetry comparison CPAP and free breathing.

Secondary outcome measures

Cardiac dosimetry with CPAP as compared to free breathing

Confirm maintenance of inflation with CPAP using surface guidance

Measure breast/chest wall or lung tumor motion as well as organ at risk motion

+2 more

Trial Design

2Treatment groups

Active Control

Group I: Lung SBRTActive Control3 Interventions

Participants will come in for their regularly scheduled radiation planning and treatment. Participants will undergo three scans (with and without DIBH (i.e., free-breathing), with CPAP). Participants will also use the CPAP device before the CT scan, for which they will be educated and trained.

Group II: left-sided breast cancerActive Control3 Interventions

0 / 5Eligibility criteria met

Find a Location

Who is running the clinical trial?

Case Comprehensive Cancer CenterLead Sponsor

452 Previous Clinical Trials

31,820 Total Patients Enrolled

Varian Medical SystemsIndustry Sponsor

58 Previous Clinical Trials

3,649 Total Patients Enrolled

Chirag Shah, MDPrincipal InvestigatorCleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center

2 Previous Clinical Trials

123 Total Patients Enrolled

Media Library

Continuous Positive Airway Pressure Clinical Trial Eligibility Overview. Trial Name: NCT05142358 — N/A

Lung Cancer Research Study Groups: Lung SBRT, left-sided breast cancer

Lung Cancer Clinical Trial 2023: Continuous Positive Airway Pressure Highlights & Side Effects. Trial Name: NCT05142358 — N/A

Continuous Positive Airway Pressure 2023 Treatment Timeline for Medical Study. Trial Name: NCT05142358 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many participants are receiving this experimental treatment?

"Affirmative, the data hosted on clinicaltrials.gov confirms that this medical study is presently seeking patient recruitment. This trial was first listed on December 1st 2022 and has been recently updated on September 26th of the same year. The investigation requires 90 individuals to be enrolled at a single location."

Answered by AI

Is enrollment open for this experiment?

"Evidently, this medical trial is presently recruiting participants as per the details hosted on clinicaltrials.gov. It was first published on December 1st 2022 and has been recently adjusted on September 26th 2022."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

A Prospective Study to Evaluate Continuous Positive Airway Pressure Devices to Reduce Pulmonary Dose

2022. "A Prospective Study to Evaluate Continuous Positive Airway Pressure Devices to Reduce Pulmonary Dose". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05142358.

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