Glucosyl-Hesperidin for Exercise Performance
(HES Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to evaluate how glucosyl-hesperidin (CitraPeak), a supplement, affects exercise performance, recovery, mood, sleep, and more in recreationally active adults. Participants will receive either one of two doses of the supplement or a placebo to compare outcomes. The study seeks adults who have exercised regularly for at least 180 minutes a week over the past six months and are in good health without major medical conditions. As an unphased trial, it offers a unique opportunity to contribute to understanding the supplement's potential benefits for active individuals.
Do I need to stop taking my current medications for this trial?
If you are currently taking statin drugs or hypertension medications, you cannot participate in this trial. The protocol does not specify about other medications, so it's best to discuss with the study team.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Research shows that detailed safety information about glucosyl-hesperidin in humans is lacking. This means there is limited direct evidence on how well people tolerate it. However, the study's "Not Applicable" phase suggests the treatment is likely considered safe enough for general testing without specific safety data from different phases.
Glucosyl-hesperidin is also under investigation for its effects on exercise performance and recovery. Ongoing research suggests the treatment is generally well-tolerated, but specific details on side effects or adverse reactions are not provided. Prospective participants should consult their doctor before joining a trial to ensure it is appropriate for them.12345Why are researchers excited about this trial?
Researchers are excited about glucosyl-hesperidin (CITRAPEAK®) because it's a natural compound that might enhance exercise performance, recovery, and cognitive function. Unlike typical performance enhancers that often rely on stimulants or ergogenic aids, glucosyl-hesperidin is a flavonoid derived from citrus fruits, offering a potentially safer and more natural alternative. Additionally, its unique mechanism of action involves improving blood flow and reducing inflammation, which could provide significant benefits for athletes without the side effects commonly associated with current options. The study is exploring two different doses, 200 mg and 400 mg, to determine the most effective strategy for maximizing these benefits.
What evidence suggests that glucosyl-hesperidin might be an effective treatment for exercise performance?
Research has shown that glucosyl-hesperidin, the main ingredient in CitraPeak, might improve exercise performance and recovery. Studies suggest it can boost blood flow, helping muscles receive more oxygen and nutrients during workouts, potentially enhancing endurance and reducing fatigue. Some early research also hints at benefits for brain function, suggesting it might aid focus and mental clarity during and after exercise. Regarding mood and sleep, improved blood flow might have positive effects, but further studies are needed to confirm this. In this trial, participants will receive either 200 mg or 400 mg of glucosyl-hesperidin daily, or a placebo, to evaluate its effects on exercise performance, recovery, and cognitive function. Overall, glucosyl-hesperidin is being explored as a promising supplement for active individuals.
Who Is on the Research Team?
Chad M Kerksick, PhD
Principal Investigator
Lindenwood University
Are You a Good Fit for This Trial?
This trial is for recreationally active adults interested in the potential benefits of CitraPeak on exercise performance and recovery. Participants should be healthy with no major medical issues that affect blood flow, stress levels, cognition, or exercise ability.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive daily supplementation of glucosyl-hesperidin (CITRAPEAK) for 8 weeks, with assessments including exercise performance tests, blood flow analysis, and cognitive evaluations
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Glucosyl-Hesperidin (CitraPeak)
Find a Clinic Near You
Who Is Running the Clinical Trial?
Lindenwood University
Lead Sponsor
Increnovo, LLC
Collaborator
Increnovo, LLC
Industry Sponsor