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Domvanalimab + Zimberelimab for Liver Cancer
Study Summary
This trial is exploring if a drug combo can help treat advanced liver and bile duct cancers that didn't respond to other treatments. #ClinicalTrial
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Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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- I had treatment targeting a specific area of my cancer and met all required conditions.I do not have dementia or any mental condition that affects my ability to consent.I have not had any autoimmune diseases requiring systemic treatment in the past 2 years.I have an active tuberculosis infection.My cancer can be measured by scans.I have not had major surgery or serious injury in the last 28 days.My diagnosis is liver or bile duct cancer, but not fibrolamellar HCC or combined HCC-cholangiocarcinoma.My advanced cancer cannot be treated with surgery or localized therapies, or it has worsened after such treatments.I can provide a recent biopsy or surgery sample taken within the last 3 years.I haven't taken steroids or immunosuppressants in the last 14 days.I have brain metastases but they are under control.I have had a liver transplant.I am HIV positive.My thyroid condition cannot be controlled with medication.My cancer has spread beyond its original location.I am 18 years old or older.I have not received any live vaccines in the last 28 days.My liver cancer is not caused by a virus, or it's due to hepatitis B or C.My liver function is moderately good.My organs and bone marrow are working well.I have received a COVID-19 vaccine (vector, protein subunit, or nucleic acid).I agree to use effective birth control during the study.My cancer did not respond or came back after treatment with anti-PD-1/L1 therapy.I have not had any cancer, except for treatable local cancers, in the last 2 years.I can carry out all my daily activities without help.
- Group 1: Zimberelimab and Domvanalimab
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Have the FDA sanctioned Zimberelimab and Domvanalimab?
"After careful consideration, the Power team has deemed Zimberelimab and Domvanalimab to have a safety score of 2 due to limited evidence regarding efficacy in Phase 2 trials."
Are there still vacancies available for individuals to participate in this medical trial?
"Data from clinicaltrials.gov indicates that this medical trial is still open for enrollment, the original listing having been listed on June 1st 2023 with a recent update on June 2nd 2023."
What is the current enrollment status for this clinical experiment?
"Affirmative, as is evidenced by the details provided on clinicaltrials.gov; this research study began accepting participants June 1st of 2023 and was recently updated two days later. The trial requires 58 volunteers from a single medical centre to take part in it."
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