This trial is evaluating whether autologous skin fibroblasts will improve 1 primary outcome and 1 secondary outcome in patients with Wounds. Measurement will happen over the course of 6 months.
This trial requires 80 total participants across 1 different treatment group
This trial involves a single treatment. Autologous Skin Fibroblasts is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are in Phase 2 and have already been tested with other people.
"There are many different treatments used to treat wounds, depending on the nature of the wound and the individual's healing ability. Many wounds require a skin graft to close the wound. Some wounds may need to be covered by sutures or gauze and can require several months to heal." - Anonymous Online Contributor
"In 2001, the US was experiencing a major increase in the number of amputations across racial and ethnic groups. This was disproportionately experienced in African American men. Amputation was experienced by 3.8% of US males and 0.3% of US females. There were significantly larger absolute numbers of individuals who experienced amputations for traumatic compared with nontraumatic causes in all groups." - Anonymous Online Contributor
"Signs may present at different times during the healing process. For example, bruising may be a sign of excessive tearing of blood vessels in response to stress that often follows surgery. Scars may develop after surgery because of excessive tearing of blood vessels or in response to long periods of healing." - Anonymous Online Contributor
"There is no evidence of wound-healing property of electroacupuncture. The study provides insight into the role of wound healing in EA therapy for somatic pain, which has long been a subject of debate. Besides, we are in a position to ascertain the effects of EA on regeneration." - Anonymous Online Contributor
"Wounds, commonly caused by traumatic and non-traumatic circumstances, are an important global community health issue. The current understanding of wounds is very limited. Inadequate knowledge of wounds presents a challenge to global health. Research into the epidemiology, burden and care of wounds will enable governments and policymakers to formulate effective public health policies. A global plan is urgently needed for improving wound care." - Anonymous Online Contributor
"There is evidence of a relationship between some types of infection and increased incidence of colon cancer. It may be due to a possible relationship between bacteria, diet or infections or, alternatively, there may be a common link between infections and colitis. question: What causes gingivitis? answer: It appears that the aetiology of gingivitis is multifactorial, with both genetic and environmental factors. The data also show a strong association between smoking and gingivitis. Some findings are suggestive of a link between periodontal disease and periodontal plaque and gingivitis." - Anonymous Online Contributor
"Clinical trials are still being conducted on a fairly regular basis. However, the overwhelming majority of the wounds currently studied in the literature have failed to demonstrate an effect when randomized comparison to placebo is applied. There is still considerable scope for improvement in clinical trial design for this topic. Power makes it convenient to explore how much a clinical trial for wound healing is affected by factors such as your wound type, type of dressing, method of dressing, timing, and so on. [Power]: http://www.withpower.com/clinical-trials/wounds is a powerful and informative platform for exploring wound healing." - Anonymous Online Contributor
"Autologous skin fibroblasts of an adult age usually have a positive impact and can be a new cell therapy for all skin diseases where cells are necessary. It is worthwhile to study this treatment approach in more detail." - Anonymous Online Contributor
"Our studies showed that the method can be used as a simple and reproducible method for the production of healthy skin cells that can be used to support the recovery process after burn injury. The cells can be produced for use as a skin substitute, as they have the properties of both fibroblastic and dermal layers." - Anonymous Online Contributor
"The most notable new insight is that the human skin microbiome seems to have a role in the initiation and severity of acute and chronic wounds." - Anonymous Online Contributor
"[Without a doubt] wounds are the most common and most common injuries, but our data also showed that they are one of the injuries which can be neglected. Results from a recent clinical trial brought up the need to revise our attitudes, by incorporating more awareness and education about wounds. This would lead us to take a more active role in patient's follow-up, and it is also needed to implement a policy-making system which is more flexible and has to be updated every three years. We also needed to rethink our attitudes towards care providers." - Anonymous Online Contributor
"The use of autologous fibroblasts in a wound dressing resulted in significant gains in health-related quality of life and self-esteem. These improvements were maintained beyond the immediate 2-month period on which the dressing was used. There were also significant gains in pain and itching perception. Use of autologous skin fibroblasts is a simple method for improving quality of life after the loss of such a complex limb. It is inexpensive and readily available." - Anonymous Online Contributor