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Testicular Tissue Freezing for Children with Cancer

N/A

Recruiting

Led By Candace F Granberg

Research Sponsored by Mayo Clinic

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be male 0-17 years of age

Be younger than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 10-20 years

Awards & highlights

Study Summary

This trialaims to freeze and store testicular tissue for boys at risk of infertility due to medical treatment.

Who is the study for?

This trial is for boys aged 0-17 at risk of infertility due to medical treatments or conditions affecting the testicles. It's open to those with a high, intermediate, or low risk of prolonged azoospermia (no sperm), and those needing surgery that may impact fertility. Participants must have two testicles if they're having one removed just for preservation.Check my eligibility

What is being tested?

The trial is studying the process of freezing testicular tissue in young males who are at risk of losing their reproductive potential due to cancer treatments or other medical interventions. The goal is to preserve future fertility by storing this tissue before it's damaged.See study design

What are the potential side effects?

There may be risks associated with anesthesia and surgical procedures required for harvesting and preserving the testicular tissue, but specific side effects related to cryopreservation itself are not detailed.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am a boy under 18 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 10-20 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~10-20 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and 10-20 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Number of pregnancies and live births after transplantation of cryopreserved testicular tissue

Trial Design

1Treatment groups

Experimental Treatment

Group I: Testicular tissueExperimental Treatment1 Intervention

Children faced with a fertility threatening diagnosis or treatment plan will be offered testicular tissue cryopreservation, particularly if pre-pubescent and without other options to preserve fertility.

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

Mayo ClinicLead Sponsor

3,208 Previous Clinical Trials

3,766,950 Total Patients Enrolled

Candace F GranbergPrincipal InvestigatorMayo Clinic

Media Library

Testicular tissue cryopreservation Clinical Trial Eligibility Overview. Trial Name: NCT02872532 — N/A

Cancer Research Study Groups: Testicular tissue

Cancer Clinical Trial 2023: Testicular tissue cryopreservation Highlights & Side Effects. Trial Name: NCT02872532 — N/A

Testicular tissue cryopreservation 2023 Treatment Timeline for Medical Study. Trial Name: NCT02872532 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

To what extent can participants join this medical experiment?

"Affirmative, the information housed on clinicaltrials.gov indicates that this trial is actively recruiting patients. It was initially posted in August 2016 and has been amended most recently in November 2022. A total of 100 individuals from a single medical centre are required for enrollment purposes."

Answered by AI

Is this research endeavor presently recruiting volunteers?

"Affirmative. According to clinicaltrials.gov, this research trial is actively seeking volunteers since it was posted on August 16th 2016 and the most recent update happened on November 7th 2022. The team needs 100 participants from only 1 medical facility."

Answered by AI

Who qualifies to become part of this research experiment?

"This trial is searching for 100 minors (aged 0-17) with cancer. To qualify, the participants must meet certain criteria such as: 1) being male and 2) having either a medical condition or malignancy that requires removal of the testicles; 3) having genetic/autoimmune issues resulting in fertility decline; 4) having newly diagnosed or recurrent disease affecting fertility - provided they have not received therapy likely to lead to permanent loss of testicular function. Moreover, those who are scheduled to receive chemotherapy or radiation treatment should fall into one of three risk categories: high (>80% chance of prolonged azoospermia), intermediate"

Answered by AI