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Deep Brain Stimulation for Parkinson's Disease (CANADA Trial)
CANADA Trial Summary
This trial is testing a new type of DBS that automatically adjusts stimulation parameters based on the patient's clinical condition. The hypothesis is that this new DBS will be better than traditional DBS at treating symptoms like freezing of gait, speech impairment, and falls.
CANADA Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.CANADA Trial Design
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Who is running the clinical trial?
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- You have severe mental health issues like depression or dementia.You are using a specific type of electrical stimulation that would interfere with the study treatment.I'm sorry, but this criterion seems to be incomplete or unclear. It's difficult to provide a plain and simple explanation without more context or details. If you can provide more information or clarify the criterion, I'd be happy to help.You need to replace the device that sends electrical pulses to your body because the battery is running out of power.Your walking, balance, or speech problems get worse when the deep brain stimulation (DBS) is turned on, and get better when it's turned off.The brain signal can be measured accurately after a specific device is replaced with another one.You had deep brain stimulation surgery, but it did not use Medtronic products.You have other health problems that could affect the study results, like bone or joint issues.You have been treated for Parkinson's disease with a specific type of brain stimulation using a Medtronic lead.You have trouble walking, balancing, or speaking, as determined by the doctor and yourself.
- Group 1: Continuous DBS
- Group 2: Adaptive DBS
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Does this scientific experiment accept participants who are 35 years of age or older?
"The requirements stipulate that participants must be aged 18 to 80. There are 27 studies offered for minors and 484 specifically tailored towards seniors."
Does my profile meet the requirements for participating in this experiment?
"This clinical trial is recruiting 10 participants who are between 18 and 80 years old, diagnosed with Parkinson's disease. In order to be eligible for the study, patients must consent to its protocols as well as require an implantable pulse generator (IPG) replacement due to battery end of life. Furthermore, they should exhibit disabling gait or balance issues that worsen when DBS is on; have contacts 1 & 2 used in one hemisphere and 9 & 10 in the other; and present a good LFP signal after IPG replacement with Percept."
Is enrollment for this experiment still being accepted?
"Clinicaltrials.gov has indicated that this clinical trial is not currently looking for candidates; the initial post was published on January 1st 2023 and it underwent its last edit on November 2nd 2022. Despite this, there are 487 other studies actively recruiting patients at present."
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