Popular Trials
Laser Therapy
Thulium Fiber vs MOSES Holmium Laser for Enlarged Prostate
This trial compares two laser treatments for men with an enlarged prostate. These treatments aim to remove excess prostate tissue with less bleeding and faster recovery than traditional methods. One treatment uses a Thulium laser, while the other uses a Holmium laser.
PAE + Radiation for Prostate Cancer
This trial is testing whether a new treatment for prostate cancer, called Prostatic Artery Embolization (PAE), is effective. PAE will be given to patients before they start radiation therapy. Patients will be followed for six and twelve weeks after PAE to see how well the treatment works.
Device
iTind vs UroLift for Enlarged Prostate
This trial aims to compare the safety of the iTind device with UroLift for men who have urinary problems because of an enlarged prostate. The iTind device temporarily reshapes the prostate tissue to help improve urine flow. iTIND is the second-generation version of a temporary implantable device, which is one of the latest minimally invasive surgeries available to treat bothersome lower urinary tract symptoms caused by benign prostate enlargement.
Device
Zenflow Spring System for Enlarged Prostate
This trial aims to test the safety and effectiveness of the Zenflow Spring System, a device designed to help men with an enlarged prostate urinate more easily. The spring is placed in the urinary tract to keep it open, reducing symptoms with minimal side effects. The target group is men who suffer from urinary problems due to an enlarged prostate.
Device
Optilumeā¢ BPH Catheter System for Enlarged Prostate
This trial is testing a special catheter designed to treat men with an enlarged prostate. The device helps to open up the urinary passage, making it easier to urinate. The goal is to see if this treatment is safe and effective for these patients.
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Trials for Enlarged Prostate Patients
Procedure
Traditional vs Top-Down HoLEP for Enlarged Prostate
This trial will compare the two most common types of surgery for treating an enlarged prostate. HoLEP is a newer, less invasive type of surgery that has a shorter hospital stay, but a longer learning curve for surgeons. The "Top-Down" HoLEP technique is a novel technique which offers potential benefits to the Traditional HoLEP procedure, including decreased complexity, a reduced learning curve.
Particle Embolic
Embozene Microspheres for Genital Diseases
The purpose of this project is to evaluate the safety, efficacy, and feasibility of performing prostatic artery embolization (PAE) using endovascular techniques and particle embolics in men suffering from lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH).
Beta-3 Adrenoceptor Agonist
Mirabegron +1 More for Overactive Bladder
This trial is testing a new OAB treatment combining a Ī²3-adrenoceptor agonist (mirabegron) with an Ī±-blocker. The goal is to see if this is a safe and effective treatment for OAB symptoms in male patients with BPH.
Thermal Therapy
Prolieve for Enlarged Prostate
The primary objective of the post-marketing study is to collect safety and effectiveness data for 5 years on subjects treated with ProlieveĀ®. The collection of 5-year safety information will be used to evaluate the occurrence of any long-term side effects from the treatment. The collection of long-term effectiveness data on subjects treated with ProlieveĀ® will provide information on the long-term effects of treatment and time to re- treatment (any treatment initiated for BPH since Prolieve'" treatment, including a second treatment with Prolieve").
Trials for BPH Patients
Particle Embolic
Embozene Microspheres for Genital Diseases
The purpose of this project is to evaluate the safety, efficacy, and feasibility of performing prostatic artery embolization (PAE) using endovascular techniques and particle embolics in men suffering from lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH).
Implantable Device
Zenflow Spring System for Benign Prostatic Hyperplasia
This trial is testing the Zenflow Spring System, a small device that helps men with urinary problems due to an enlarged prostate. It works by keeping the urinary pathway open, making it easier to urinate. The Zenflow Spring System is a novel device designed to alleviate lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH).
Trials With No Placebo
Procedure
Traditional vs Top-Down HoLEP for Enlarged Prostate
This trial will compare the two most common types of surgery for treating an enlarged prostate. HoLEP is a newer, less invasive type of surgery that has a shorter hospital stay, but a longer learning curve for surgeons. The "Top-Down" HoLEP technique is a novel technique which offers potential benefits to the Traditional HoLEP procedure, including decreased complexity, a reduced learning curve.
Particle Embolic
Embozene Microspheres for Genital Diseases
The purpose of this project is to evaluate the safety, efficacy, and feasibility of performing prostatic artery embolization (PAE) using endovascular techniques and particle embolics in men suffering from lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH).
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Frequently Asked Questions
Introduction to benign prostatic hyperplasia
What are the top hospitals conducting benign prostatic hyperplasia research?
When it comes to cutting-edge clinical trials addressing benign prostatic hyperplasia (BPH), hospitals across the United States are making notable contributions. In Cleveland, Ohio, University Hospitals Cleveland Medical Center takes the lead with one active BPH trial and an equally impressive history of conducting a single trial for this condition thus far. This medical center has demonstrated its commitment to advancing research in BPH since recording its first trial in 2023. Similarly, UH Brainard Medical Bldg in Lyndhurst and UH Regional Hospitals - Richmond Campus in Richmond Heights have also embarked on their own respective active BPH trials and hold a record of one completed trial eachāboth initiated in 2023.
Moving northward to Thunder Bay Regional Health Sciences Centre situated in Thunder Bay, Canada, we find another medical facility dedicated to exploring solutions for individuals affected by BPH. With one ongoing clinical trial focused on this condition and having commenced their inaugural investigation back in 2022, this center is actively contributing to expanding our understanding of potential treatments for the condition.
Finally, located southwards all away down into Hialeah is Urology Specialist Group where they too are pioneering similar efforts towards finding resolutions tending only one current clinical experiment alongside having successfully conducted singular such investigations since way back as 2020.
These hospitals represent beacons of hope for those suffering from BPH while exemplifying dedication towards advancements within urological health care. Although there may appear few active trials presently underway across these institutions collectively, it's essential to acknowledge that every initiative contributes substantially toward enhanced patient outcomes and better quality of life moving forward
Which are the best cities for benign prostatic hyperplasia clinical trials?
For benign prostatic hyperplasia clinical trials, several cities have emerged as leaders in research and development. Thunder Bay, Ontario takes the lead with 2 active trials investigating treatments such as Thulium Fibre Laser and Top-Down HoLEP. Following closely behind is Cleveland, Ohio, along with its neighboring cities Lyndhurst and Richmond Heights, each hosting 1 active trial focused on Intravesical Botox injection among other interventions. Additionally, Hialeah, Florida joins the ranks with 1 ongoing trial exploring SoracteLite(TM) TPLA for BPH. These cities offer individuals affected by benign prostatic hyperplasia opportunities to participate in cutting-edge clinical trials that strive for improved treatment options and better quality of life.
Which are the top treatments for benign prostatic hyperplasia being explored in clinical trials?
Clinical trials exploring potential treatments for benign prostatic hyperplasia (BPH) have brought several promising options to the forefront. Prostate Artery Embolization, a procedure designed to shrink the prostate gland by blocking its blood supply, is currently being tested in two active trials and has been involved in five all-time BPH trials since its introduction in 2014. Intravesical Botox injection, a minimally invasive treatment that involves injecting botulinum toxin directly into the bladder wall, shows promise with one active trial and one all-time trial dedicated to BPH research since its first listing in 2023. Thulium Fibre Laser therapy and SoracteLite(TM) TPLA are also undergoing investigation through clinical trials for their efficacy against BPH, each with one active trial and one all-time study focused on this condition. As these studies progress, they provide hope for improved management of benign prostatic hyperplasia.
What are the most recent clinical trials for benign prostatic hyperplasia?
Recent clinical trials offer promising advancements in the treatment of benign prostatic hyperplasia (BPH). A Phase 4 trial explores a new treatment group specifically tailored for BPH, potentially providing improved outcomes for patients. Additionally, SoracteLite(TM) TPLA is being investigated in a Phase 1 study as a potential therapeutic option for BPH. These innovative trials aim to address the challenges associated with this condition and enhance patient care.
What benign prostatic hyperplasia clinical trials were recently completed?
Recently completed clinical trials for benign prostatic hyperplasia have provided valuable insights into potential treatment options. In September 2019, Urovant Sciences GmbH successfully concluded a trial investigating the efficacy of Vibegron in addressing this condition. Similarly, another trial sponsored by Urovant Sciences GmbH reached completion in March 2019 and also focused on evaluating the effects of Vibegron. These important studies shed light on the ongoing efforts to find innovative therapeutic approaches for individuals with benign prostatic hyperplasia.