Rezum vs UroLift for Enlarged Prostate
(CLEAR Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
C.L.E.A.R. Study is poised to compare the patient experience post procedure, including catheterization needs as well as retreatment and BPH medication rates following treatment with either the UroLift® System or Rezūm™ System through 12 months.
Do I have to stop taking my current medications for the trial?
The trial protocol does not specify whether you need to stop taking your current medications.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What safety data exists for Rezum and UroLift treatments for enlarged prostate?
The safety data for Rezum and UroLift treatments for benign prostatic hyperplasia (BPH) indicate that both procedures are minimally invasive and have been evaluated in various studies. Rezum, a water vapor therapy, has shown significant and durable improvements in urinary and sexual function over five years, with low reintervention rates and a safe profile across different patient groups. UroLift, a prostatic urethral lift, maintains higher sexual function scores compared to some other treatments. Both treatments have similar urinary and sexual outcomes at 24 months, with no significant differences in complication rates. Real-world evidence supports the safety and efficacy of Rezum across a broad range of prostate volumes.12345
Is Rezum or UroLift safe for treating an enlarged prostate?
Is the treatment Rezum or UroLift a promising treatment for an enlarged prostate?
Yes, both Rezum and UroLift are promising treatments for an enlarged prostate. They are minimally invasive and help improve urinary symptoms. Rezum uses water vapor to treat the prostate, while UroLift lifts and holds the prostate tissue. Both treatments have shown similar improvements in urinary symptoms over time.12467
How do Rezum and UroLift treatments for enlarged prostate differ from other treatments?
Rezum and UroLift are minimally invasive treatments for enlarged prostate (BPH) that do not require general anesthesia, unlike more invasive surgeries like TURP. Rezum uses water vapor to ablate prostate tissue, while UroLift involves lifting and holding the enlarged prostate tissue away from the urethra to improve urine flow. Both treatments aim to reduce urinary symptoms with less impact on sexual function compared to traditional surgeries.12467
What data supports the idea that Rezum vs UroLift for Enlarged Prostate is an effective treatment?
The available research does not provide any data on Rezum or UroLift for treating an enlarged prostate. The studies listed focus on other conditions and treatments, such as pediatric vesicoureteral reflux, upper tract urothelial carcinoma, and prostate cancer-related issues. Therefore, no specific data from these studies can be used to support the effectiveness of Rezum or UroLift for an enlarged prostate.89101112
Are You a Good Fit for This Trial?
Men over 50 with symptoms of an enlarged prostate (30cm3 to 80cm3 in size) who haven't had previous BPH surgery, don't have a urinary infection or severe bleeding, and aren't part of another study. Those with certain urethra conditions, a penile prosthesis, or urinary sphincter implant are excluded.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either the UroLift or Rezūm procedure
Post-procedure Assessment
Participants complete voiding assessments and questionnaires at specified intervals
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Rezum
- UroLift
Rezum is already approved in United States, European Union for the following indications:
- Benign Prostatic Hyperplasia (BPH)
- Benign Prostatic Hyperplasia (BPH)
Find a Clinic Near You
Who Is Running the Clinical Trial?
NeoTract, Inc.
Lead Sponsor