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Study Summary
This trial is designed to see if a new biomarker can help predict which patients will respond to exposure-based therapy for anxiety, OCD and stress-related disorders.
- Agoraphobia
- Obsessive-Compulsive Disorder
- Panic Disorder
- Post-Traumatic Stress Disorder
- Social Anxiety Disorder
- Generalized Anxiety Disorder
Eligibility Criteria
Inclusion Criteria
You will be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Awards & Highlights
Trial Design
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Who is running the clinical trial?
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- You are pregnant or currently breastfeeding.You have an anxiety score of 8 or higher on a test called the OASIS.You have had thoughts of hurting or killing yourself in the past 6 months and may have taken steps towards doing so.You are currently receiving therapy for your main mental health condition.You have certain medical conditions that make it unsafe for you to breathe in CO2 or hyperventilate, such as heart problems, asthma, lung disease, high blood pressure, epilepsy, or stroke.You have been diagnosed with a mental health condition such as panic disorder, social anxiety disorder, generalized anxiety disorder, obsessive-compulsive disorder, or post-traumatic stress disorder. The diagnosis was made using a specific interview called the Structured Clinical Interview for the DSM-5 (SCID-5).You have a history of bipolar disorder, psychotic disorders, substance abuse, or an eating disorder within the past 6 months. You also have significant problems with memory, thinking, or learning.
- Group 1: Open Exposure-Based Therapy (EBT)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 1 Weeks to process to see if you qualify in this trial.
- Treatment: You will receive the treatment for 12 Weeks
- Follow Ups: You may be asked to continue sharing information regarding the trial for 3 Months after you stop receiving the treatment.
Frequently Asked Questions
Am I eligible to participate in this experiment?
"This medical study requires 600 individuals with Obsessive-Compulsive Disorder (OCD) aged between 18 and 70 to participate. Eligibility is further restricted by a DSM-5 diagnosis, an OASIS score of 8 or higher, proficiency in English, as well as the willingness and capacity for informed consent."
How many individuals are enrolled in this experiment?
"Affirmative. According to clinicaltrials.gov, this experiment is recruiting individuals as of November 2nd 2022 and requires 600 participants from two sites. It was first posted on the same date and has been periodically renewed since then."
Is this trial currently open to new enrollees?
"According to clinicaltrials.gov, this medical trial is presently accepting participants as of its most recent edit on November 2nd 2022. The experiment was initially posted the same day for recruitment purposes."
Does this investigation seek individuals aged 25 and up?
"The current study accepts patients aged 18 to 70, with 377 trials targeting those under the age of majority and 1107 for individuals over 65."
Who else is applying?
What state do they live in?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
Why did patients apply to this trial?
What questions have other patients asked about this trial?
How responsive is this trial?
Typically responds via
Most responsive sites:
- The University of Texas at Austin: < 48 hours
Average response time
- < 2 Days
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