Laser Therapy
Thulium Fiber vs MOSES Holmium Laser for Enlarged Prostate
This trial compares two laser treatments for men with an enlarged prostate. These treatments aim to remove excess prostate tissue with less bleeding and faster recovery than traditional methods. One treatment uses a Thulium laser, while the other uses a Holmium laser.
Device
iTind vs UroLift for Enlarged Prostate
This trial aims to compare the safety of the iTind device with UroLift for men who have urinary problems because of an enlarged prostate. The iTind device temporarily reshapes the prostate tissue to help improve urine flow. iTIND is the second-generation version of a temporary implantable device, which is one of the latest minimally invasive surgeries available to treat bothersome lower urinary tract symptoms caused by benign prostate enlargement.
Device
Zenflow Spring System for Enlarged Prostate
This trial aims to test the safety and effectiveness of the Zenflow Spring System, a device designed to help men with an enlarged prostate urinate more easily. The spring is placed in the urinary tract to keep it open, reducing symptoms with minimal side effects. The target group is men who suffer from urinary problems due to an enlarged prostate.
Device
Optilumeā¢ BPH Catheter System for Enlarged Prostate
This trial is testing a special catheter designed to treat men with an enlarged prostate. The device helps to open up the urinary passage, making it easier to urinate. The goal is to see if this treatment is safe and effective for these patients.
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Trials for Enlarged Prostate Patients
Procedure
Traditional vs Top-Down HoLEP for Enlarged Prostate
This trial will compare the two most common types of surgery for treating an enlarged prostate. HoLEP is a newer, less invasive type of surgery that has a shorter hospital stay, but a longer learning curve for surgeons. The "Top-Down" HoLEP technique is a novel technique which offers potential benefits to the Traditional HoLEP procedure, including decreased complexity, a reduced learning curve.
Particle Embolic
Embozene Microspheres for Genital Diseases
The purpose of this project is to evaluate the safety, efficacy, and feasibility of performing prostatic artery embolization (PAE) using endovascular techniques and particle embolics in men suffering from lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH).
Beta-3 Adrenoceptor Agonist
Mirabegron +1 More for Overactive Bladder
This trial is testing a new OAB treatment combining a Ī²3-adrenoceptor agonist (mirabegron) with an Ī±-blocker. The goal is to see if this is a safe and effective treatment for OAB symptoms in male patients with BPH.
Thermal Therapy
Prolieve for Enlarged Prostate
The primary objective of the post-marketing study is to collect safety and effectiveness data for 5 years on subjects treated with ProlieveĀ®. The collection of 5-year safety information will be used to evaluate the occurrence of any long-term side effects from the treatment. The collection of long-term effectiveness data on subjects treated with ProlieveĀ® will provide information on the long-term effects of treatment and time to re- treatment (any treatment initiated for BPH since Prolieve'" treatment, including a second treatment with Prolieve").
Trials for BPH Patients
Particle Embolic
Embozene Microspheres for Genital Diseases
The purpose of this project is to evaluate the safety, efficacy, and feasibility of performing prostatic artery embolization (PAE) using endovascular techniques and particle embolics in men suffering from lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH).
Implantable Device
Zenflow Spring System for Benign Prostatic Hyperplasia
This trial is testing the Zenflow Spring System, a small device that helps men with urinary problems due to an enlarged prostate. It works by keeping the urinary pathway open, making it easier to urinate. The Zenflow Spring System is a novel device designed to alleviate lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH).
Trials With No Placebo
Procedure
Traditional vs Top-Down HoLEP for Enlarged Prostate
This trial will compare the two most common types of surgery for treating an enlarged prostate. HoLEP is a newer, less invasive type of surgery that has a shorter hospital stay, but a longer learning curve for surgeons. The "Top-Down" HoLEP technique is a novel technique which offers potential benefits to the Traditional HoLEP procedure, including decreased complexity, a reduced learning curve.
Particle Embolic
Embozene Microspheres for Genital Diseases
The purpose of this project is to evaluate the safety, efficacy, and feasibility of performing prostatic artery embolization (PAE) using endovascular techniques and particle embolics in men suffering from lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH).
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Frequently Asked Questions
Introduction to bph
What are the top hospitals conducting bph research?
When it comes to clinical trials focused on finding new treatments for benign prostatic hyperplasia (BPH), several hospitals across different locations are making significant contributions. In Cleveland, the University Hospitals Cleveland Medical Center leads the way with 1 active BPH trial and a total of 1 trial conducted since recording their first one in 2023. Another facility within the same healthcare system, UH Brainard Medical Building in Lyndhurst, is also actively involved in BPH research with similar numbers of ongoing and completed trials. Similarly, at UH Regional Hospitals - Richmond Campus in Richmond Heights, researchers are conducting an active BPH trial while having completed one previously recorded trial.
Moving outside Ohio, Thunder Bay Regional Health Sciences Centre located in Thunder Bay has made substantial progress as well. This Canadian hospital has an ongoing BPH trial and has successfully conducted one prior study since their initial recorded trial back in 2022. Lastly, the Urology Specialist Group based in Hialeah contributes to advancing our understanding of BPH through its involvement in current and past trials focusing on this condition.
Although these specific hospitals may have limited data available for bph clinical trials at present, they demonstrate a commitment to researching better solutions for patients dealing with this common urological issue characterized by enlargement of the prostate gland that can cause urinary symptoms such as frequent urination or weak urine flow. It's important to recognize that medical advancements take time and require meticulous investigation before reaching conclusive results; nonetheless, the dedication shown by these institutions signifies promising steps towards improving treatment options for those affected by BPH.
Which are the best cities for bph clinical trials?
When it comes to bph clinical trials, several cities show promise in advancing research and treatment options. Thunder Bay, Ontario stands out with 2 active trials examining therapies like the Thulium Fibre Laser and Top-Down HoLEP. Cleveland, Ohio along with its neighboring towns of Lyndhurst and Richmond Heights also contribute to the effort with 1 active trial each focusing on Intravesical Botox injection. Additionally, Hialeah, Florida offers a study on SoracteLite(TM) TPLA for BPH. These cities provide individuals with opportunities to participate in cutting-edge clinical trials that may lead to improved management strategies for benign prostatic hyperplasia (BPH).
Which are the top treatments for bph being explored in clinical trials?
Exciting developments in the field of BPH treatment are emerging from ongoing clinical trials. Prostate Artery Embolization, a procedure that involves blocking blood flow to the prostate to reduce its size, is currently being explored in two active trials and has accumulated five all-time BPH trials since 2014. Another promising option is Intravesical Botox injection, with one active trial underway. Thulium Fibre Laser also shows potential with one active trial investigating its efficacy for BPH treatment. Lastly, SoracteLite(TM) TPLA for BPH has shown promise in one active trial since its introduction in 2020. These innovative treatments offer hope for patients suffering from this common condition and may provide effective alternatives to traditional approaches such as medication or surgery.
What are the most recent clinical trials for bph?
Recent clinical trials have offered new insights and potential treatment options for individuals with benign prostatic hyperplasia (BPH). One noteworthy trial is evaluating a treatment group specifically designed to address the symptoms associated with BPH. Another study focuses on SoracteLite(TM) TPLA, a novel approach that shows promise in managing BPH. These trials highlight the ongoing efforts to improve patient outcomes and quality of life in those affected by this condition.
What bph clinical trials were recently completed?
Two recent clinical trials have explored potential treatments for benign prostatic hyperplasia (BPH). In September 2019, Urovant Sciences GmbH completed a trial investigating the efficacy of Vibegron. Another trial sponsored by the same company concluded in March 2019 and also focused on evaluating Vibegron's effectiveness for BPH. These studies contribute to our understanding of therapeutic options for individuals experiencing this condition and may pave the way for improved management strategies in the future.