Anosmia Clinical Trials 2023
Browse 5 Anosmia Medical Studies Across 5 Cities
5 Anosmia Clinics
Beclomethasonefor Post-Covid Hyposmia
Treatmentfor Loss of Smell
Aerosolized 13 Cis Retinoic Acid And Vitamin Dfor Anomia
Smell Retrainingfor Loss of Smell
What Are Anosmia Clinical Trials
Anosmia is a sensory disorder defined by loss of smell. The condition can indirectly impact taste, but it is not categorized as ageusia (loss of taste). For some, the condition is temporary, but for others, it can be permanent. Some people only lose some of their smell but retain some function.
According to Johns Hopkins, sense disorders can be a result of the following:
- Illness, such as CoVid
- Cocaine uses
- Smoking cigarettes
- Radiation therapy for throat or head cancers
- Some medications
- Nasal polyps
- Dental issues
- Hormone changes
- Injuries to the head
Clinical trials for anosmia examine various methods to treat the condition, including smell retraining.
Why Is Anosmia Being Studied Through Clinical Trials?
According to the National Institute on Deafness and Other Communication Disorders, 23% of adults over 40 in the US had some alternation of smell. 12.4% had enough alteration to be considered measurable.
According to a 2023 paper in the Journal of NeuroVirology_, _instances of anosmia sharply increased in 2020 with the spread of CoVid-19. For some patients, the anosmia improves after 2-3 weeks. However, according to the Cleveland Clinic, 15% of patients still have a loss of smell 60 days later. Consequently, research into the disorder has risen, and many focuses on the most effective forms of smell retraining.
What Are The Types Of Treatments Available For Anosmia?
According to the Mayo Clinic, treatment for anosmia depends on the cause. For example, it clears up in a few days when it is caused by a cold or allergies. In addition, antibiotics are used to treat bacterial infections that cause loss of smell.
In the event there is a blockage, removing the item resolves the problem. However, sometimes the blockage is caused by inflammation rather than an object, polyps, or a tumor, and steroids can help.
However, not all anosmia can be treated.
CoVid-19 has brought new challenges to treating anosmia. According to a 2023 comprehensive review published in Cureus, researchers and healthcare providers are exploring many ways to help their patients regain their sense of smell. These potential treatments include some of the following:
- Intranasal insulin films
- Nasal fluticasone spray
- Nasal betamethasone drops
- Olfactory training
However, these are still being studied, and some are showing more promising results than others.
What Are Some Recent Breakthrough Clinical Trials For Anosmia?
2023: Electrical Stimulation: Researchers at the Medical University of South Caroline investigated if electrical stimulation of the trigeminal nerve could improve olfaction. The study involved 20 healthy adults who, through randomization, were treated with trigeminal never stimulation (TNS), transcranial direct current stimulation (tDCDS), or sham.
Results showed that TNS is safe, simple, and noninvasive.
2023: Olfactory Training in CoVid-19 Patients – Researchers from Europe, including the Department of Otolaryngology at Polyclinic of Poitiers, ran a study in three medical centers in France, Belgium, and Italy to examine the effectiveness of olfactory training (OT) in people with dysfunction resulting from CoVid-19.
57 patients completed the entire 18-month evaluation process. Of that total, 32 adhered to the full OT training. The results concluded that the training provided better mid-term improvements.