CYR-064 for Loss of Smell
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial is testing a new treatment called CYR-064 to see if it is safe and works well. About 150 people will take part in the study. The trial will last several months, including initial checks, treatment, and follow-up periods.
Will I have to stop taking my current medications?
The trial requires participants to stop using any over-the-counter or prescription medications administered intranasally, except for nasal saline. Other medications may need to be stopped if the investigator believes they could affect safety or compliance with the study.
Is theophylline safe for human use?
How is the drug CYR-064 (Theophylline) unique in treating loss of smell?
CYR-064 (Theophylline) is unique because it is a phosphodiesterase inhibitor that can improve smell function by increasing levels of certain molecules (cAMP and cGMP) in nasal mucus, which are often low in people with smell loss. Unlike other treatments, it can be administered both orally and intranasally, offering flexibility in treatment options.13467
What data supports the effectiveness of the drug CYR-064 for loss of smell?
Who Is on the Research Team?
Mas Takashima, MD
Principal Investigator
The Methodist Hospital Research Institute
Are You a Good Fit for This Trial?
This trial is for men and women aged 18-65 who've lost their sense of smell but don't have any nasal blockages or diseases causing it. They must be able to take the study drug themselves and follow the trial's procedures.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either CYR-064 or placebo nasal solution twice a day for 24 weeks
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- CYR-064
Find a Clinic Near You
Who Is Running the Clinical Trial?
Cyrano Therapeutics, Inc.
Lead Sponsor