SGB for Post-traumatic Stress Disorder

Phase-Based Progress Estimates
Post-traumatic Stress DisorderStellate Ganglion Block - Procedure
18 - 55
All Sexes
What conditions do you have?

Study Summary

This trial will assess whether or not Stellate Ganglion Block (SGB), a treatment established to relieve pain, can also help reduce the symptoms of Posttraumatic Stress Disorder (PTSD).

Eligible Conditions
  • Post-traumatic Stress Disorder

Treatment Effectiveness

Study Objectives

2 Primary · 1 Secondary · Reporting Duration: 8 weeks after SGB, Sham, or WLC enrollment

Week 8
Clinician Administered PTSD Scale-5
Peripheral Psychophysiology Startle Response
Safety - Adverse Events and Side Effects from Treatment

Trial Safety

Trial Design

3 Treatment Groups

Wait-List Control (WLC)
1 of 3
1 of 3
1 of 3

Active Control

Non-Treatment Group

360 Total Participants · 3 Treatment Groups

Primary Treatment: SGB · Has Placebo Group · N/A

Wait-List Control (WLC)NoIntervention Group · 1 Intervention: Wait-List Control (WLC) · Intervention Types:
ShamComparator Group · 1 Intervention: Sham Stellate Ganglion Block · Intervention Types: Procedure
ActiveComparator Group · 1 Intervention: Stellate Ganglion Block · Intervention Types: Procedure

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 8 weeks after sgb, sham, or wlc enrollment

Who is running the clinical trial?

Analydata, IncUNKNOWN
1 Previous Clinical Trials
93 Total Patients Enrolled
VA Office of Research and DevelopmentLead Sponsor
1,485 Previous Clinical Trials
2,741,859 Total Patients Enrolled
13 Trials studying Post-traumatic Stress Disorder
1,478 Patients Enrolled for Post-traumatic Stress Disorder
Michael Hollifield, MDPrincipal InvestigatorVA Long Beach Healthcare System, Long Beach, CA
2 Previous Clinical Trials
183 Total Patients Enrolled

Eligibility Criteria

Age 18 - 55 · All Participants · 8 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You will be eligible if you have not completed the EBT due to aversion
You have PTSD with a total CAPS-5 score of > 26.
You have had at least one trial of an evidence-based treatment (EBT) for PTSD.
You have symptoms of PTSD that are common in the general population.

Who else is applying?

What state do they live in?
How old are they?
18 - 65100.0%
What site did they apply to?
William S. Middleton Memorial Veterans Hospital, Madison, WI100.0%
What portion of applicants met pre-screening criteria?
Met criteria100.0%