SGB for Post-traumatic Stress Disorder

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Post-traumatic Stress DisorderStellate Ganglion Block - Procedure
Eligibility
18 - 55
All Sexes
What conditions do you have?
Select

Study Summary

This trial will assess whether or not Stellate Ganglion Block (SGB), a treatment established to relieve pain, can also help reduce the symptoms of Posttraumatic Stress Disorder (PTSD).

Eligible Conditions
  • Post-traumatic Stress Disorder

Treatment Effectiveness

Study Objectives

2 Primary · 1 Secondary · Reporting Duration: 8 weeks after SGB, Sham, or WLC enrollment

Week 8
Clinician Administered PTSD Scale-5
Peripheral Psychophysiology Startle Response
Safety - Adverse Events and Side Effects from Treatment

Trial Safety

Trial Design

3 Treatment Groups

Wait-List Control (WLC)
1 of 3
SGB
1 of 3
Sham
1 of 3

Active Control

Non-Treatment Group

360 Total Participants · 3 Treatment Groups

Primary Treatment: SGB · Has Placebo Group · N/A

Wait-List Control (WLC)NoIntervention Group · 1 Intervention: Wait-List Control (WLC) · Intervention Types:
Sham
Procedure
ShamComparator Group · 1 Intervention: Sham Stellate Ganglion Block · Intervention Types: Procedure
SGB
Procedure
ActiveComparator Group · 1 Intervention: Stellate Ganglion Block · Intervention Types: Procedure

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 8 weeks after sgb, sham, or wlc enrollment

Who is running the clinical trial?

Analydata, IncUNKNOWN
1 Previous Clinical Trials
93 Total Patients Enrolled
VA Office of Research and DevelopmentLead Sponsor
1,485 Previous Clinical Trials
2,741,859 Total Patients Enrolled
13 Trials studying Post-traumatic Stress Disorder
1,478 Patients Enrolled for Post-traumatic Stress Disorder
Michael Hollifield, MDPrincipal InvestigatorVA Long Beach Healthcare System, Long Beach, CA
2 Previous Clinical Trials
183 Total Patients Enrolled

Eligibility Criteria

Age 18 - 55 · All Participants · 8 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You will be eligible if you have not completed the EBT due to aversion
You have PTSD with a total CAPS-5 score of > 26.
You have had at least one trial of an evidence-based treatment (EBT) for PTSD.
You have symptoms of PTSD that are common in the general population.

Who else is applying?

What state do they live in?
Wisconsin100.0%
How old are they?
18 - 65100.0%
What site did they apply to?
William S. Middleton Memorial Veterans Hospital, Madison, WI100.0%
What portion of applicants met pre-screening criteria?
Met criteria100.0%