TcMS for Tachycardia

Phase-Based Progress Estimates
Hospital of the University of Pennsylvania, Philadelphia, PA
Tachycardia+2 More
TcMS - Device
All Sexes
What conditions do you have?

Study Summary

This study is evaluating whether a non-invasive treatment can be used to treat ventricular tachycardia.

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Eligible Conditions

  • Tachycardia
  • Ventricular Tachycardia (VT)

Treatment Effectiveness

Study Objectives

This trial is evaluating whether TcMS will improve 1 primary outcome and 2 secondary outcomes in patients with Tachycardia. Measurement will happen over the course of 0-72 hours after enrollment.

0-72 hours after enrollment
Non sustained ventricular tachycardia
Ventricular Tachycardia
Assessed immediately following stimulation

Trial Safety

Trial Design

1 Treatment Group

Transcutaneous magnetic stimulation
1 of 1
Experimental Treatment

This trial requires 100 total participants across 1 different treatment group

This trial involves a single treatment. TcMS is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Transcutaneous magnetic stimulation
Transcutaneous magnetic stimulation targeting the stellate ganglion

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 0-72 hours after enrollment
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 0-72 hours after enrollment for reporting.

Closest Location

Hospital of the University of Pennsylvania - Philadelphia, PA

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 2 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Age >18years
The text states that the person has had ventricular tachycardia within the past 72 hours. show original

Patient Q&A Section

What causes tachycardia, ventricular?

"Tachycardias associated with myocardial infarction are caused predominantly by abnormalities in excitable tissues in the heart and are unrelated to damage to the ventricular myocytes." - Anonymous Online Contributor

Unverified Answer

How many people get tachycardia, ventricular a year in the United States?

"About 1.6 million persons each year in the U.S. receive a diagnosis of ischemic heart disease. Half of these cases occur in persons in their twenties and thirties. The remaining half has less specific clinical symptoms. About 636,000 a year die from cardiac causes. The majority of these deaths occur in the twenties and thirties. These data provide strong evidence that heart disease prevention should begin before the age of 30 years." - Anonymous Online Contributor

Unverified Answer

What are the signs of tachycardia, ventricular?

"In most people with a palpable extraocular mass or an intracranial lesion, Tachycardia, Ventricular is present. While most individuals with tachycardia, Ventricular without palpitation would be found to be benign, palpitation may indicate more significant pathology." - Anonymous Online Contributor

Unverified Answer

What are common treatments for tachycardia, ventricular?

"There is a great deal of variability and comorbidity among tachycardia patients and treatment often combines pharmacology with nonpharmacological therapies to minimize side effects. Patient selection is very important to treatment failure. Although newer agents are under investigation, the traditional agents are still effective and widely used." - Anonymous Online Contributor

Unverified Answer

What is tachycardia, ventricular?

"Tachycardia, Ventricular is the name given to a heart rhythm characterized by higher than normal heart rate. Tachycardia is usually defined as a heart rate greater than 100 BPM. Ventricular tachycardia is characterized by a heart rate of 180 or greater BPM. Ventricular tachycardia can usually be sustained for a long period of time. Tachycardia, Ventricular may be diagnosed by the following symptoms:\n1. Signs of low blood pressure (unless accompanied by low blood sodium/choline or low blood potassium/acidosis)\n2. Signs of low blood oxygen level (in most conditions)\n3." - Anonymous Online Contributor

Unverified Answer

Can tachycardia, ventricular be cured?

"The present study does not support the use of VEGF in the treatment of atrial or ventricular tachycardia. This finding is in agreement with recent data from the Efficacy and Safety of Vascular Endothelial Growth Factor in Ischemic Heart Disease (VEGFOR HOPE) trial. Therefore, patients who require VEGF to improve clinical status cannot be considered for VEGF therapy, at least as currently defined." - Anonymous Online Contributor

Unverified Answer

Does tcms improve quality of life for those with tachycardia, ventricular?

"The TCM tachycardia management program reported in this study substantially improved the QOL of patients with tachycardia, ventricular with reduced quality of life independently from HRV parameters. Further studies are necessary to evaluate the appropriateness of TCM treatments beyond tachycardia cases and to clarify the role of HRV parameters in modifying the QOL." - Anonymous Online Contributor

Unverified Answer

What is tcms?

"Data from a recent study shows that the ventricular tachycardia pattern observed is a more widespread phenomenon and its identification may improve the management of patients who suffer VT and its association to a high rate of arrhythmic events. We suggest the application of automatic rhythm interpretation algorithms to VT and their integration in the routine interpretation of electrocardiograms in the ambulatory monitoring of patients with VT or the recognition of the presence of tics signs in the clinical context, especially in patients prone to a sudden cardiac death." - Anonymous Online Contributor

Unverified Answer

What are the latest developments in tcms for therapeutic use?

"The advances in the field of biomedical sciences have pushed the envelope of human medicine exponentially. With innovations in medical technology and knowledge of basic knowledge, it was not so long ago that [transcutaneous electrical nerve stimulation (tnus)|tnus] was first developed to enhance the treatment of patients with refractory [tachycardia related to ventricular arrhythmias]. In the same manner that [adenosine triphosphate (ATP) receptor|ATP receptor] was being targeted by [aplastic anemia (no longer recognized as an entity)|aplastic anemia] researchers have begun to tinker with [a-b current] to treat patients with cardiac dysrhythmias." - Anonymous Online Contributor

Unverified Answer

Is tcms typically used in combination with any other treatments?

"There was no advantage of adding tcms to the first-line antiarrhythmic regimen in patients with VT or bradycardia. However, in patients with VT or tachycardia due to a primary arrhythmia other than arrhythmogenic right ventricular dysplasia, tcms provided a short-term benefit in relieving symptoms and in prolonging the length of time spent in sinus rhythm." - Anonymous Online Contributor

Unverified Answer

Have there been any new discoveries for treating tachycardia, ventricular?

"There is a very little advancement in the treatment of ventricular tachycardia, particularly when it comes to rhythm control with ablation. Ablation, despite being the preferred management for ventricular tachycardia, has a high failure rate and may result in life threatening arrhythmias. Ablation therapy is most commonly performed during the early stages of catheter ablation but can be performed at any stage of the procedure. Tachycardia is a symptom associated with the heart muscle and can be treated with medications only if other treatments for tachycardia have failed or do not restore a normal heart rhythm." - Anonymous Online Contributor

Unverified Answer

Who should consider clinical trials for tachycardia, ventricular?

"The use of a clinical trial (or clinical trial registry) as an instrument by which physicians can determine whether and how to use medications for their clients has become quite popular in an era of escalating health expenditures. As such, there will be an ever increasing number of participants to be enlisted into any given clinical trial. As such, clinicians and researchers would benefit if they have a greater understanding of the basics of using clinical trials for the purpose of treatment. Clinical trials, which are often of necessity tedious, expensive, and time-consuming, should be undertaken with a view towards achieving the objectives of those conducting them, as well as to the interests of those whose well-being they affect." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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