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TMS for Post-Traumatic Stress Disorder

N/A

Waitlist Available

Led By Norman B Schmidt, PhD

Research Sponsored by Florida State University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Over 18 years of age

Report clinically significant posttraumatic stress disorder (PTSD) symptoms (score of ≥ 33 on the PTSD Checklist for DSM-5 [PCL-5]).

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 5 hours

Awards & highlights

Study Summary

This trial tests whether PTSD patients have difficulty controlling their thoughts & emotions, & how this affects their mental health.

Who is the study for?

This trial is for adults over 18 with significant PTSD symptoms, who have experienced a traumatic event. It's not suitable for those with metal in their head, seizure disorders, brain tumors, strokes, aneurysms, multiple sclerosis or unstable medical conditions. People with OCD as a primary diagnosis or active substance use issues are also excluded.Check my eligibility

What is being tested?

The study is examining the effects of Transcranial Magnetic Stimulation (TMS) on cognitive control deficits in individuals suffering from PTSD. TMS is a non-invasive procedure that uses magnetic fields to stimulate nerve cells in the brain.See study design

What are the potential side effects?

TMS may cause discomfort at the site of stimulation, headache, lightheadedness or tingling. In rare cases it can induce seizures or hearing loss if ear protection isn't used during treatment.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am over 18 years old.

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I have severe PTSD symptoms based on a specific checklist score.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 5 hours

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~5 hours

This trial's timeline: 3 weeks for screening, Varies for treatment, and 5 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Performance on emotional working memory task

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Intermittent theta burst stimulation to right dorsolateral prefrontal cortexExperimental Treatment1 Intervention

Participants will receive intermittent theta burst stimulation (iTBS) to the experimental target area, the right dorsolateral prefrontal cortex (rDLPFC)

Group II: Intermittent theta burst stimulation to vertex of the skullActive Control1 Intervention

Participants will receive intermittent theta burst stimulation (iTBS) to the active comparator area, the vertex of the skull

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Transcranial Magnetic Stimulation (TMS)

2018

Completed Phase 4

~570

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Florida State UniversityLead Sponsor

198 Previous Clinical Trials

30,651 Total Patients Enrolled

Norman B Schmidt, PhDPrincipal InvestigatorDistinguished Research Professor

3 Previous Clinical Trials

311 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this clinical experiment allow individuals aged 25 and over to participate?

"This clinical research is seeking volunteers aged 18 and over, but under the age of 65."

Answered by AI

Is the opportunity available to join this medical experiment?

"This trial seeks to enrol 35 candidates who meet the following criteria: post-traumatic stress disorder and aged between 18–65."

Answered by AI

How many volunteers have enrolled in this clinical test?

"Affirmative. The clinicaltrials.gov website suggests that this medical research is presently recruiting participants, having initially been published on September 13th 2023 and updated most recently on the 12th of September 2023. 35 volunteers are needed from one trial site for completion of the study."

Answered by AI

Are there any available slots for this research endeavor?

"Absolutely. According to the clinicaltrials.gov website, recruitment for this examination is ongoing and began on September 13th 2023. The most recent amendment was made on 12th of that same month. A total of 35 test subjects have been requested at one location thus far."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Testing a Causal Model of Cognitive Control Deficits in Posttraumatic Stress Disorder (PTSD)

Carter Bedford 2023. "Testing a Causal Model of Cognitive Control Deficits in Posttraumatic Stress Disorder (PTSD)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06016673.