TMS over the left prefrontal cortex for Approach/Avoidance Behavior

Phase-Based Progress Estimates
University of Minnesota, Minneapolis, MN
Approach/Avoidance Behavior
Transcranial magnetic stimulation (TMS) - Device
All Sexes
What conditions do you have?

Study Summary

The purpose of this study is to evaluate the causal link between the phase of ongoing theta oscillations in the prefrontal cortex and approach/avoidance (Ap/Av) behavior in adults using theta phase-specific transcranial magnetic stimulation (TMS).

Treatment Effectiveness

Study Objectives

1 Primary · 1 Secondary · Reporting Duration: Immediate effect during stimulation

Immediate effect during stimulation
Amplitude of TMS evoked potentials
Reaction times in the Approach/Avoidance test

Trial Safety

Trial Design

2 Treatment Groups

TMS over the left prefrontal cortex
1 of 2
TMS over the head vertex
1 of 2
Experimental Treatment
Non-Treatment Group

26 Total Participants · 2 Treatment Groups

Primary Treatment: TMS over the left prefrontal cortex · Has Placebo Group · N/A

TMS over the left prefrontal cortex
Experimental Group · 1 Intervention: Transcranial magnetic stimulation (TMS) · Intervention Types: Device
TMS over the head vertex
ShamComparator Group · 1 Intervention: Transcranial magnetic stimulation (TMS) · Intervention Types: Device
First Studied
Drug Approval Stage
How many patients have taken this drug
Transcranial magnetic stimulation (TMS)
Completed Phase 4

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: immediate effect during stimulation
Closest Location: University of Minnesota · Minneapolis, MN
Photo of University of Minnesota   1Photo of University of Minnesota   2Photo of University of Minnesota  3
1993First Recorded Clinical Trial
1 TrialsResearching Approach/Avoidance Behavior
828 CompletedClinical Trials

Eligibility Criteria

Age 18+ · All Participants · 2 Total Inclusion Criteria

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You are eligible for the study if you are between the ages of 18 and 65 years old.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.