Transcranial magnetic stimulation (TMS) for Post Traumatic Stress Disorder (PTSD)

Phase-Based Progress Estimates
NYU Langone Health, New York, NY
Post Traumatic Stress Disorder (PTSD)
Transcranial magnetic stimulation (TMS) - Device
All Sexes
What conditions do you have?

Study Summary

This study aims to explore the mechanisms of how transcranial magnetic stimulation (TMS) impacts fear circuits. The overarching objectives are to understand how varying TMS parameters affect targeted brain regions in order to optimize its impact on enhancing fear extinction memory consolidation in a population with known fear extinction deficiencies: post-traumatic stress disorder (PTSD). 250 subjects will take part in this research study across NYU Langone Health. The study will include preliminary screenings, baseline visits, and experimental visits across four days

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Post Traumatic Stress Disorder (PTSD)

Study Objectives

2 Primary · 4 Secondary · Reporting Duration: Experimental Day 3

Experimental Day 3
Blood Oxygen Levels
Score on Childhood Trauma Questionnaire (CTQ)
Score on Intolerance of Uncertainty Scale (IUS-12) - Short Form
Score on Patient Health Questionnaire (PHQ-9)
Score on State-Trait Anxiety Inventory (STAI) - Form Y1
Skin Conductance Response (SCR)

Trial Safety

Safety Progress

1 of 3

Other trials for Post Traumatic Stress Disorder (PTSD)

Trial Design

2 Treatment Groups

Healthy Control group
1 of 2
PTSD group
1 of 2
Active Control
Experimental Treatment

250 Total Participants · 2 Treatment Groups

Primary Treatment: Transcranial magnetic stimulation (TMS) · No Placebo Group · N/A

PTSD group
Experimental Group · 1 Intervention: Transcranial magnetic stimulation (TMS) · Intervention Types: Device
Healthy Control group
ActiveComparator Group · 1 Intervention: Transcranial magnetic stimulation (TMS) · Intervention Types: Device
First Studied
Drug Approval Stage
How many patients have taken this drug
Transcranial magnetic stimulation (TMS)
Completed Phase 4

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: experimental day 3
Closest Location: NYU Langone Health · New York, NY
Photo of NYU Langone Health  1Photo of NYU Langone Health  2Photo of NYU Langone Health  3
2020First Recorded Clinical Trial
4 TrialsResearching Post Traumatic Stress Disorder (PTSD)
107 CompletedClinical Trials

Eligibility Criteria

Age 18+ · All Participants · 8 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You are a healthy control.
You have a diagnosis of PTSD.
You have no current or past history of Axis I psychiatric disorders.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.