This trial is evaluating whether Preservative Free Morphine will improve 1 primary outcome and 4 secondary outcomes in patients with Depression. Measurement will happen over the course of 1 week.
This trial requires 140 total participants across 2 different treatment groups
This trial involves 2 different treatments. Preservative Free Morphine is the primary treatment being studied. Participants will all receive the same treatment. Some patients will receive a placebo treatment. The treatments being tested are in Phase 4 and have been shown to be safe and effective in humans.
"Different maternal and family factors may influence the development of depression in women after delivery, especially for younger women. It is also recommended that mothers and families should be given appropriate information and support, such as education, and family treatment." - Anonymous Online Contributor
"Depression and postpartum is an unrecognized, yet important, and often undertreated health problem in the postpartum woman. Postpartum depression treatment may result in a significant reduction of depression in the first month postpartum, which in the long term may have positive impact on maternal and child health." - Anonymous Online Contributor
"The study identified that the prevalence and impact of postpartum depression is high. However, to decrease postpartum depression, education about the nature of postpartum depression, and of how to deal with it is important to health care professionals and women, to aid them in the recovery process." - Anonymous Online Contributor
"During the postpartum period, women report a range of symptoms, including fatigue, weight loss, nausea, low energy, moodiness and anxiety. Some symptoms also correlate with the severity of postpartum depression. This information is important for women when considering seeking help with symptoms and clinicians when addressing postpartum depression with postpartum women. Subjective indicators of postpartum depression, such as increased levels of anxiety, can aid clinicians with identifying postpartum women at risk of developing depression when evaluating for postpartum depression." - Anonymous Online Contributor
"Specific solutions for each individual patient will be dependent on their health status and treatment needs, but the mainstays to treatment include medication, counselling, and psychotherapy. In addition to these interventions, health educators may contribute to effective treatment for women with depression, postpartum." - Anonymous Online Contributor
"Over 14 million American women have depression in the first year after giving birth. Although there are many women that get depression after a baby's birth, the number is on the decline. However, many of these women still need to consult with a physician." - Anonymous Online Contributor
"Although many new treatments have been developed, few have reached clinical use. In the future, we should focus on developing new treatments aimed at specific populations, such as women who are obese, who experienced a complicated delivery, or whose child was delivered by a high-risk obstetrician." - Anonymous Online Contributor
"Depression and postpartum depression deserve clinical trials. Data from a recent study of those trials will enable our physicians to better evaluate the treatment of those disorders." - Anonymous Online Contributor
"There is no difference in the number of side effects, the rate of withdrawal, or the need for rescue medication when using a preservative free morphine preparation for [pain management](https://www.withpower.com/clinical-trials/pain-management) during childbirth. Preservative free morphine may improve patient adherence to pain medication for the first 6 hours after delivery, which is important to decreasing the need for rescue medication." - Anonymous Online Contributor
"Recent findings points at an overall low risk of developing major depressive disorder or major postpartum depression. The risk of developing major depression postpartum is greatest among depressed women with a history of major depression, postpartum depression or a family history of major depression." - Anonymous Online Contributor
"In this randomized controlled trial, preservative free morphine did not significantly improve patient-reported nausea/vomiting scores. Preservative free morphine does not improve nausea/vomiting when used as a preemptive for postoperative analgesia in patients undergoing laparoscopic cholecystectomy." - Anonymous Online Contributor
"The findings from this systematic review suggest that there have been some advancements in research on the prevention and treatment of depression postpartum and that further research should be continued. Recent findings from this review may be useful for the development of effective guidelines for managing depression following postpartum." - Anonymous Online Contributor