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Opioid Analgesic

Fentanyl vs. Morphine for Platelet Reactivity

Phase < 1
Recruiting
Research Sponsored by Spectrum Health - Lakeland
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Administered aspirin within 30 minutes of the initial blood draw
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 hours
Awards & highlights

Study Summary

This trial is studying whether fentanyl & morphine have similar effects on aspirin's effect on platelets in chest pain patients in the ER.

Who is the study for?
This trial is for adults in the emergency department with chest discomfort who are undergoing specific heart tests, have taken aspirin recently, and arrived by private vehicle. It's not for those already on certain blood thinners, pregnant women, chronic narcotic users, non-English speakers or anyone previously enrolled.Check my eligibility
What is being tested?
The study is looking at how fentanyl and morphine affect the way aspirin works on platelets in patients with chest pain. Researchers want to see if fentanyl might be a better option than morphine because of potential negative effects associated with morphine.See study design
What are the potential side effects?
Possible side effects from fentanyl or morphine can include nausea, vomiting, constipation, drowsiness, confusion, respiratory depression (slow breathing), and addiction potential.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I took aspirin within 30 minutes before my first blood test.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
platelet aggregation

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: MorphineExperimental Treatment1 Intervention
the second group will be those receiving morphine
Group II: FentanylExperimental Treatment1 Intervention
the 3rd group will be those receiving fentanyl
Group III: ControlActive Control1 Intervention
not receiving any narcotics
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Morphine
2013
Completed Phase 4
~2230
Fentanyl
2019
Completed Phase 4
~1870

Find a Location

Who is running the clinical trial?

Spectrum Health - LakelandLead Sponsor
12 Previous Clinical Trials
1,699 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this trial provide eligibility to patients above the age of sixty?

"In accordance with the study's prerequisites, only individuals aged 18 and above but below 65 are eligible to join."

Answered by AI

Can I register for the clinical trial?

"To be eligible for the clinical trial, potential participants must possess a fentanyl prescription and belong to the age range of 18-65. A total of 100 individuals are required for this research endeavour."

Answered by AI

How many individuals are permitted to take part in this research project?

"Affirmative. The clinicaltrials.gov portal displays that this medical study is still open for recruitment, having first been posted on August 31st 2022 and recently updated on October 25th of the same year. 100 volunteers are needed from a single site to participate in the trial."

Answered by AI

Are there any opportunities for patients to join this research endeavor?

"This trial is presently admitting participants, as per the data hosted on clinicaltrials.gov. It was initially posted online in August of 2022 and the study details were amended most recently in October of that same year."

Answered by AI

Who else is applying?

What state do they live in?
New Mexico
What portion of applicants met pre-screening criteria?
Did not meet criteria
How many prior treatments have patients received?
1

Why did patients apply to this trial?

I've tried everything that they've asked me to as far as therapy, medication nothing is working it's excruciating pain nothing helps nothing.I suffer every day and on top of having RA I also have systemic lupus.
PatientReceived 2+ prior treatments
Recent research and studies
clinicaltrials.govStudy
Platelet Reactivity With Fentanyl, Morphine, or no Narcotic
2022. "Platelet Reactivity With Fentanyl, Morphine, or no Narcotic". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05367336.
~0 spots leftby May 2024
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