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Intermittent Theta Burst Stimulation for Depression (iTBS Trial)

Q: Are there still vacancies available for participation in this experiment?

The details found on clinicaltrials.gov reveal that this study cannot accept any more patients; the protocols were first established in December 2017, and last updated in May of 2022. Fortunately, 1298 other medical trials are currently searching for candidates.

Q: What qualifications must one fulfill to participate in this experiment?

To qualify for this research, potential participants must be between 22 and 65 years old with a diagnosis of melancholia. Currently, the investigators need to recruit 30 volunteers in total.

Q: Does this experiment have an age limitation, and if so, is it higher than 45 years?

Prospective participants must be between 22 and 65 years old to qualify for this study.

N/A

Waitlist Available

Research Sponsored by University of California, Los Angeles

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up two week

Awards & highlights

iTBS Trial Summary

This trial will test whether a new treatment, intermittent Theta Burst Stimulation, is effective for patients with Major Depressive Disorder.

Eligible Conditions

Depression

iTBS Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ two week

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~two week

This trial's timeline: 3 weeks for screening, Varies for treatment, and two week for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Percent change in Hamilton Depression Scale (HamD17)

iTBS Trial Design

3Treatment groups

Experimental Treatment

Active Control

Placebo Group

Group I: Open-labelExperimental Treatment1 Intervention

Theta burst stimulation (TBS) is a form of repetitive transcranial magnetic stimulation (TMS). Standard TBS parameters consisting of 3-pulse, 50Hz bursts every 200 ms (5 Hz) at an intensity of 80% motor threshold (MT) will be utilized. Intermittent TBS will be delivered in 2-second trains of bursts repeated every 10 seconds for a total of 570 seconds (1800 pulses) in each session. Each treatment session thus involves < 10 minutes of stimulation. The subject and researchers know what treatment is being administered.

Group II: Blinded ActiveActive Control1 Intervention

Standard TBS parameters consisting of 3-pulse, 50Hz bursts every 200 ms (5 Hz) at an intensity of 80% motor threshold (MT) will be utilized. Intermittent TBS will be delivered in 2-second trains of bursts repeated every 10 seconds for a total of 570 seconds (1800 pulses) in each session. Each treatment session thus involves < 10 minutes of stimulation. The subject and researcher will not know what type of treatment will be administered.

Group III: Blinded ShamPlacebo Group1 Intervention

This is a sham treatment which will mimic the open-label and blinded active to enable the effects of the supposedly "active" treatment to be assessed objectively. The subject and researcher will not know what type of treatment will be administered. Each treatment session will be < 10 minutes in duration.

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Who is running the clinical trial?

University of California, Los AngelesLead Sponsor

1,529 Previous Clinical Trials

10,277,772 Total Patients Enrolled

101 Trials studying Depression

48,413 Patients Enrolled for Depression

Media Library

Neuronetics XPLOR system (Other) Clinical Trial Eligibility Overview. Trial Name: NCT02506127 — N/A

Depression Research Study Groups: Open-label, Blinded Sham, Blinded Active

Depression Clinical Trial 2023: Neuronetics XPLOR system Highlights & Side Effects. Trial Name: NCT02506127 — N/A

Neuronetics XPLOR system (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT02506127 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there still vacancies available for participation in this experiment?

"The details found on clinicaltrials.gov reveal that this study cannot accept any more patients; the protocols were first established in December 2017, and last updated in May of 2022. Fortunately, 1298 other medical trials are currently searching for candidates."

Answered by AI

What qualifications must one fulfill to participate in this experiment?

"To qualify for this research, potential participants must be between 22 and 65 years old with a diagnosis of melancholia. Currently, the investigators need to recruit 30 volunteers in total."

Answered by AI