This trial is evaluating whether intermittent theta burst stimulation will improve 1 primary outcome and 1 secondary outcome in patients with Depression. Measurement will happen over the course of through study completion, an average of 10 days.
This trial requires 30 total participants across 4 different treatment groups
This trial involves 4 different treatments. Intermittent Theta Burst Stimulation is the primary treatment being studied. Participants will be divided into 2 treatment groups. Some patients will receive a placebo treatment. The treatments being tested are in Phase < 1 and are in the first stage of evaluation with people.
"Most people report feeling unwell, especially emotionally, and they also report problems with personal and family function. It is crucial that GPs recognize the signs and symptoms of depression to enable timely diagnosis." - Anonymous Online Contributor
"Patients with depression do not have a specific gene on which to rest. However, patients who have a stressful or traumatic past are at a greater risk of having symptoms in their lifetime. Furthermore, patients who have low socioeconomic status are at a higher risk." - Anonymous Online Contributor
"Depression is a mental disorder that can affect daily functioning. Depressed parents may have a difficult time coping with the depression. Depression usually starts with the child. Depression treatment may help the child learn strategies to help themselves and their parents through therapy and coping skills." - Anonymous Online Contributor
"There is a significant number of individuals who meet either the ICD-10 or DSM-IV criteria for major depressive disorder. However, it is unknown whether these individuals suffer significant psychosocial or functional impairment. Further research into these questions is warranted." - Anonymous Online Contributor
"Antidepressants are often prescribed and self-medicated to treat depression. A significant number of depressed persons have co-morbid anxiety disorders such that specific antidepressants are more appropriate." - Anonymous Online Contributor
"About 10% of men with depressed mood have depressive symptoms during their life; however, if they go untreated, about 80% of depressed men will develop major depression. Depression may be caused by stressful circumstances that are difficult to control. Depression can cause the depressed person to feel like a burden to other people on account of what he or she is already doing for them. Depression is also associated with marital problems and financial hardship and can cause suicidal thoughts, which can then trigger the onset of suicide or attempt. Depression can result in a person failing to take advantage of the right opportunity as well as not focusing on the future and having a lower standard of living." - Anonymous Online Contributor
"Data from a recent study of our survey indicate that patients are not satisfied by many clinical trials and that patient participation in clinical trials should not be limited only to randomized controlled trials. Trials in which nonrandomized or not randomized patients are included appear to have a significant impact on the results." - Anonymous Online Contributor
"The data illustrate the relative safety of the use of TBS on most of the common side effects experienced with other forms of tDCS, specifically headaches, sleep disturbances and alterations in tremor. A prospective study with a larger sample size is required to further clarify the most commonly reported side effects, especially the subjective ones." - Anonymous Online Contributor
"CTBS is a non-invasive method of inducing long lasting changes of cortico-limbic communication. The data support evidence that CTBS can induce persistent inhibition of a single motor cortex brain rhythm. In contrast, the results also suggest that alterations induced by CTBS are transient and restricted to certain rhythmic components of ipsilateral cortical oscillatory EEG." - Anonymous Online Contributor
"In our studies we used anodal BTABS only for the treatment of depression and did not use it in combination with other treatments. This suggests that anodal BTABS used alone might be sufficient to treat depression." - Anonymous Online Contributor
"In this small sample, CTS was effective for improving depression and QOL. Further studies are needed to determine the effectiveness of CTS versus traditional antidepressant treatment in improving QOL, and to establish the optimal frequency of stimulation to maximize benefits over time." - Anonymous Online Contributor