Treatment Resistant Depression Clinical Trials
Here are the 6 most popular medical studies for treatment resistant depression
Behavioral Intervention
Internet-Based Psychological Support for Depression
This trial will assess the feasibility, acceptability and effectiveness of PATH, an internet-based, multimedia-intensive, computer-based treatment program that includes modules on problem-solving, stress management, and conflict management.
Behavioural Intervention
Psycho-education & Understanding Bipolar Medications Therapy + MBSR + ISRT + Bipolar-Specific CBT for Bipolar Disorder
This trial will study how to better treat bipolar patients who are suicidal by looking at environmental and psychological factors, as well as implementing a 6-week intervention program.
Behavioral Intervention
Parenting Interventions for Early Childhood Development
This trial tests an integrated approach to promoting school readiness in low-income families, beginning shortly after the child's birth. The intervention is delivered through the pediatric primary care platform and includes two evidence-based interventions: 1) a universal primary prevention strategy (Video Interaction Project [VIP]); and 2) a targeted secondary/tertiary prevention strategy (Family Check-up [FCU]) for families with infants/toddlers identified as having additional risks.
Behavioural Intervention
Phototherapy for Depression
This trial will help to clarify the mechanisms underlying the antidepressant effects of phototherapy and will provide valuable information about the potential role of sleep in the antidepressant response to bright light therapy.
Popular filter options for treatment resistant depression trials
Depression Clinical Trials
View 97 Depression medical studies.
Omega-3 Fatty Acids
Vitamin D + Omega-3 for Depression
This trial is studying whether taking vitamin D3 or omega-3 fatty acids supplements reduces the risk of developing cancer, heart disease, and stroke. This study will also examine whether either of these supplements reduces the risk of clinical depression or improves mood scores over time.
Behavioral Intervention
Physical Activity and Education for Colorectal Cancer
This trial is studying a physical activity program given together with health education materials to see how well it works compared with giving health education materials alone for patients who have undergone treatment for high-risk stage II or stage III colon cancer.
Major Depressive Disorder Clinical Trials
View 97 Major Depressive Disorder medical studies.
Omega-3 Fatty Acids
Vitamin D + Omega-3 for Depression
This trial is studying whether taking vitamin D3 or omega-3 fatty acids supplements reduces the risk of developing cancer, heart disease, and stroke. This study will also examine whether either of these supplements reduces the risk of clinical depression or improves mood scores over time.
Behavioral Intervention
Physical Activity and Education for Colorectal Cancer
This trial is studying a physical activity program given together with health education materials to see how well it works compared with giving health education materials alone for patients who have undergone treatment for high-risk stage II or stage III colon cancer.
Treatment Resistant Depression Clinical Trials With No Placebo
View 97 treatment resistant depression medical studies that do not have a placebo group.
Behavioral Intervention
Physical Activity and Education for Colorectal Cancer
This trial is studying a physical activity program given together with health education materials to see how well it works compared with giving health education materials alone for patients who have undergone treatment for high-risk stage II or stage III colon cancer.
Behavioral Intervention
EFT for Cancer-related Anxiety and Depression
This trial is examining whether EFT coaching can help relieve symptoms of anxiety, depression, and other psychological conditions in patients with cholangiocarcinoma, a rare and terminal cancer.
View More Treatment Resistant Depression Trials
See another 79 medical studies focused on treatment resistant depression.
Frequently Asked Questions
Introduction to treatment resistant depression
What are the top hospitals conducting treatment resistant depression research?
In the realm of mental health, hospitals are making strides in finding new solutions for treatment-resistant depression. One such hospital is the Relmada Site located in sunny Miami. While it may have a modest two ongoing clinical trials and an equal number of completed trials dedicated to treatment-resistant depression, its commitment to innovation shines through as it recorded its first trial on this challenging condition just last year, in 2021. Turning our attention to Albuquerque, New mexico, we find both the University of New Mexico Family Health Clinic locations at North Valley and Southeast Heights focusing their efforts on combating treatment-resistant depression. With two active clinical trials each and an equal number of previously conducted studies, these clinics demonstrate their dedication to addressing this complex issue that affects individuals across different communities.
Further westward lies Bakersfield's Clinica Sierra Vista - Baker Street Village CHC where research into treatment-resistant depression is also being pursued with utmost vigor. Like many other institutions leading the charge against this debilitating condition, they currently have two active clinical trials underway while having completed two previous studies as well since commencing their efforts in 2021.
Lastly yet importantly contributing towards combatting resistant-depression is Clinica Sierra Vista - Kern River Health Center situated amidst Wofford Heights; sharing similar ambition like aforementioned counterparts by offering up-to-date treatments through sponsorship for current pair active clinical tests alongside already accomplishing initial duo investigations starting merely a year ago within2021
With these hospitals at the forefront of tackling treatment-resistant depression across different geographic locations, hope emerges that new breakthroughs will be discovered to provide relief and improved quality of life for those who struggle with this challenging mental health condition today
Which are the best cities for treatment resistant depression clinical trials?
When it comes to clinical trials for treatment-resistant depression, several cities emerge as top contenders for research opportunities. Albuquerque, New mexico leads the pack with 10 ongoing trials focused on interventions like Collaborative Care Plus and Collaborative Care. Following closely behind is San Diego, California, offering 8 active studies exploring treatments such as REL-1017, Family Cognitive Behavioral Prevention, and Magnetic Seizure Therapy. Los Angeles, California also showcases promising research with 7 ongoing trials investigating Proud & Empowered and Endotoxin among others. Pittsburgh, Pennsylvania contributes to the field with 7 active trials examining interventions like RxWell and Stepped Collaborative Care Intervention. Lastly, Baltimore Maryland offers valuable insights through its 6 active trials studying REL-1017 25 mg and Behavioral Activation - Rehabilitation. These cities provide individuals struggling with treatment-resistant depression access to cutting-edge clinical trials that may revolutionize care options and improve outcomes in this challenging condition.
Which are the top treatments for treatment resistant depression being explored in clinical trials?
Clinical trials are uncovering potential breakthroughs in the treatment of treatment-resistant depression. Notably, endotoxin is currently being explored in two active trials and has been a part of four all-time studies since its listing in 2014. Another promising avenue is intervention, with one ongoing trial and eight previous trials dedicated to addressing treatment-resistant depression since 2009. Additionally, external Qigong shows promise as a potential therapy for this challenging condition; it has one active trial underway after being first listed in 2023. Lastly, an innovative self-guided digital intervention for non-suicidal self-injury (NSSI) displays encouraging early results with one active trial following its introduction to clinical research in 2024. These diverse approaches offer hope for individuals grappling with treatment-resistant depression by expanding the options available for their care.
What are the most recent clinical trials for treatment resistant depression?
Recent clinical trials offer new hope for those struggling with treatment resistant depression. Notably, REL-1017 25 mg has entered Phase 3 and shows promising potential in providing relief for individuals who have not responded to conventional treatments. Additionally, endotoxin is being explored in Phase 1 as a possible solution for treatment resistance. Brexanolone has advanced to Phase 4 and offers an alternative therapy option for patients battling this challenging condition. Furthermore, duloxetine is currently undergoing Phase 2 testing to evaluate its efficacy in treating treatment-resistant depression. These ongoing studies highlight the dedication of researchers and provide renewed optimism for individuals seeking effective interventions against this debilitating mental health disorder.
What treatment resistant depression clinical trials were recently completed?
Several cutting-edge clinical trials for treatment-resistant depression have recently concluded, marking significant progress in the field. In June 2022, Alto Neuroscience completed a trial investigating the ALTO-100 PO Tablet as a potential therapy. Earlier that year, in April 2022, Washington University School of Medicine wrapped up their study on Ketamine's effectiveness. Additionally, Rebecca Price successfully completed an Intravenous Ketamine trial in February 2022. These breakthroughs underline the dedication of researchers and offer hope to individuals struggling with treatment-resistant depression.