- Anxiety
- Depression
- Alzheimer's Disease
- Weight Loss
- Heart Disease
- Cancer
- Asthma
Trial Phase
Trial Status
Paid Participation
93 Treatment Resistant Depression Trials Near You
Power is an online platform that helps thousands of Treatment Resistant Depression patients discover FDA-reviewed trials every day. Every trial we feature meets safety and ethical standards, giving patients an easy way to discover promising new treatments in the research stage.
Learn More About PowerTrial Details
Key Eligibility Criteria
147 Participants Needed
Rapid-Acting TMS for Depression
Trial Details
Key Eligibility Criteria
100 Participants Needed
Deep Brain Stimulation for Depression
Trial Details
Key Eligibility Criteria
12 Participants Needed
Why Other Patients Applied
"I've heard great things about ketamine for treatment resistant depression and PTSD but haven't been able to try it. I've been struggling to find something to alleviate my symptoms since my son passed away in 2017."
"I'm taking a medication for anxiety and it's not helping/working. I want to try and find something that would help with my anxiety. My research brought me to clinical trials."
"I tried Prozac, Lamictal, TMS, a psychotherapy, and mindfulness meditation. These treatments provided limited relief. I hope for a new treatment that will be more effective. Looking for something that lasts long-term so that I can get my life back."
"I’ve tried so many drugs and treatments for depression it won’t go away or if it does it just comes back. I want to help others who may have this awful condition while also helping myself. If something new works for me, maybe it'll work for other people too."
"I've tried 8 or 9 different combinations of antidepressants (SSRI, SNRI, etc) + antipsychotics, mood stabilizers, anxiolytics... I’ve been through on- and off-label treatments, I've had at least 4 serious side effcts in the 10 years I've been on antidepressants. I've done PGx testing for genetic markers, too. My experience finding appropriate treatment has been lonely, exhausting. I'd love to participate in something that helps others like me."
Know someone looking for new options?
Spread the word
Learn More About Power
We started Power when my dad was diagnosed with multiple myeloma, and I struggled to help him access the latest immunotherapy. Hopefully Power makes it simpler for you to explore promising new treatments, during what is probably a difficult time.
Frequently Asked Questions
How much do Treatment Resistant Depression clinical trials pay?
Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range for Phase 2–4 trials (Phase 1 trials often pay substantially more). Further, most trials will cover the costs of a travel to-and-from the clinic.
How do Treatment Resistant Depression clinical trials work?
After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll be sorted into one of the treatment groups, and receive your study drug. For some trials, there is a chance you'll receive a placebo. Across Treatment Resistant Depression trials 30% of clinical trials have a placebo. Typically, you'll be required to check-in with the clinic every month or so. The average trial length for Treatment Resistant Depression is 12 months.
How do I participate in a study as a "healthy volunteer"?
Not all studies recruit healthy volunteers: usually, Phase 1 studies do. Participating as a healthy volunteer means you will go to a research facility several times over a few days or weeks to receive a dose of either the test treatment or a "placebo," which is a harmless substance that helps researchers compare results. You will have routine tests during these visits, and you'll be compensated for your time and travel, with the number of appointments and details varying by study.
What does the "phase" of a clinical trial mean?
The phase of a trial reveals what stage the drug is in to get approval for a specific condition. Phase 1 trials are the trials to collect safety data in humans. Phase 2 trials are those where the drug has some data showing safety in humans, but where further human data is needed on drug effectiveness. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. As a general rule, Phase 3 trials are more promising than Phase 2, and Phase 2 trials are more promising than phase 1.
Do I need to be insured to participate in a Treatment Resistant Depression medical study?
Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.
What are the newest Treatment Resistant Depression clinical trials?
Most recently, we added Nitrous Oxide for Acute Suicidality, Psilocybin-Assisted Therapy for Depression and Low Frequency rTMS for Bipolar Depression to the Power online platform.
What do the "Power Preferred" and "SuperSite" badges mean?
We recognize research clinics with these awards when they are especially responsive to patients who apply through the Power online platform. SuperSite clinics are research sites recognized for a high standard of rapid and thorough follow-up with patient applicants. Meanwhile, Power Preferred clinics are the top 20 across the entire Power platform, recognized for their absolute top patient experience.
Which clinics have received Power Preferred and SuperSite awards recruiting for Treatment Resistant Depression trials?
The Treatment Resistant Depression clinics currently recognized as Power Preferred are: Adams Clinical in Watertown, Massachusetts BioBehavioral Research of Austin in Austin, Texas Cedar Clinical Research in Draper, Utah The Treatment Resistant Depression clinics currently recognized as SuperSites are: The Medical Research Network, LLC in New York, New York Boston Clinical Trials (Alcanza Network) in Boston, Massachusetts Preferred Research Partners, Fayetteville in Fayetteville, Arkansas