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Neuromodulation for Depression (TREND Trial)
TREND Trial Summary
This trial will study whether theta burst stimulation, a type of magnetic brain stimulation, can help reduce the severity of depression symptoms. A subset of participants will also receive positive affect training.
TREND Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.TREND Trial Design
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Who is running the clinical trial?
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- You have consumed a large amount of alcohol within the past week or within the last 12 hours.You have a mental health condition called obsessive-compulsive disorder, which you have had at any point in your life.You have a history of mental illness that included losing touch with reality.You are afraid of being in small or enclosed spaces.You have a medical device implanted in your body.You have a high risk of attempting suicide.You have had a problem with drugs or alcohol within the last 6 months.I am currently taking Clozapine, Bupropion, or prescription stimulants.I am currently taking benzodiazepines or mood stabilizers.You have been diagnosed with bipolar disorder at any point in your life.You are pregnant.You are too big to fit inside the MRI scanner.You use nicotine every day.I have a history of seizures.I have had a head injury that made me lose consciousness.I have a neurological disorder such as epilepsy, Parkinson's, brain tumor, brain injury, or stroke.You are currently diagnosed with Depressive Disorder according to DSM-5.You cannot have an MRI if you are too big for the scanner, have a fear of small spaces, or have metal inside your body that can be affected by the MRI's magnetic field.You have metal in your head or in other parts of your body that are attracted to magnets.
- Group 1: TBS
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How many participants are accepted into this medical trial?
"Affirmative. The information available on clinicaltrials.gov affirms that this trial is open for recruitment, having been posted initially on June 17th 2022 and last updated September 22nd of the same year. Presently, 30 participants are needed from one site."
Is there an opportunity to partake in this research?
"This trial seeks to enrol 30 individuals between 18 and 26 who suffer from a depressive disorder as defined in the Diagnostic and Statistical Manual (DSM-5)."
Are there still openings available in this research endeavor?
"Affirmative, the clinicaltrials.gov site verifies that this medical experiment is currently recruiting participants. It was originally published on June 17th 2022 and just recently updated on September 22nd of the same year. The research necessitates 30 individuals from a single centre."
Is the age range for participants in this research restricted to individuals 45 or younger?
"The eligibility for this particular study is constrained to those between 18 and 26 years old. Meanwhile, other trials are open to minors (under 18) and seniors (over 65). Specifically, 192 clinical studies exist that accept patients below the age of majority while 964 cater specifically to elderly individuals."
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