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Mangoes for Muscle Injury

N/A

Waitlist Available

Led By David C Nieman, DrPH

Research Sponsored by Appalachian State University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up change from pre-study to post-2 weeks supplementation, and immediately post-exercise, and 1.5 hours-, 3 hours-, and 24 hours-post-exercise

Awards & highlights

Study Summary

This trial will examine the effect of mangoes on mitigating exercise-induced inflammation and muscle soreness.

Eligible Conditions

Muscle Injury
Inflammation

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ change from pre-study to post-2 weeks supplementation, and immediately post-exercise, and 1.5 hours-, 3 hours-, and 24 hours-post-exercise

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~change from pre-study to post-2 weeks supplementation, and immediately post-exercise, and 1.5 hours-, 3 hours-, and 24 hours-post-exercise

This trial's timeline: 3 weeks for screening, Varies for treatment, and change from pre-study to post-2 weeks supplementation, and immediately post-exercise, and 1.5 hours-, 3 hours-, and 24 hours-post-exercise for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Plasma lipid mediators

Secondary outcome measures

Plasma inflammasome activation

Urine mango metabolites

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: MangoesExperimental Treatment1 Intervention

Frozen mangoes, 2 cups per day (with 2 cups water), 2 weeks.

Group II: WaterActive Control1 Intervention

Bottled water, 2 cups per day

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Mangoes

2022

N/A

~30

Do I qualify?Apply below to find out

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Who is running the clinical trial?

Appalachian State UniversityLead Sponsor

40 Previous Clinical Trials

2,175 Total Patients Enrolled

David C Nieman, DrPHPrincipal InvestigatorAppalachian State Univ

13 Previous Clinical Trials

638 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

To what extent is this experiment being conducted with participants?

"Affirmative. Based on the information published to clinicaltrials.gov, this clinical trial is presently enrolling participants and was posted on August 15th 2022 with a most recent update occurring October 24th 2022. The study requires 20 volunteers for 1 medical facility."

Answered by AI

Is there an opportunity to participate in this study at present?

"According to the most recent updates on clinicaltrials.gov, this medical trial is accepting participants at present. The original posting was recorded on August 15th 2022 with a final update made October 24th of that year."

Answered by AI

Are participants aged 25 or older eligible for this research trial?

"The only patients able to partake in this research study must be between 18 and 45 years of age. In contrast, those under the legal age of consent may take part in up to 28 clinical trials while the elderly can join 283 distinct experiments."

Answered by AI

What criteria must a person meet to become eligible for participation in this research?

"Right now, the trial is open to male and female cyclists aged 18-45 who can cycle for 2.25 hours at 70% VO2max. Applicants must abstain from ingesting mangoes (other than what's provided), large doses of vitamin/mineral supplements, herbs or medications that affect inflammation; in addition they should not be smokers with chronic diseases including cardiovascular disease, cancer, type 1 & 2 diabetes, nor rheumatoid arthritis according to American College of Sports Medicine screening questionnaire standards."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Mangoes and Exercise Inflammation

2022. "Mangoes and Exercise Inflammation". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05409105.