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Intermittent Hypoxia in Healthy Individuals

N/A

Waitlist Available

Led By William Rymer, PhD

Research Sponsored by Shirley Ryan AbilityLab

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

No history of neurologic injury or progressive neuromuscular disorder

Must be medically stable with no history of cardiovascular instability, congestive heart failure or stroke

Timeline

Screening 3 weeks

Treatment Varies

Follow Up immediately after acute intermittent hypoxia administration

Awards & highlights

Study Summary

This trial will examine the effect of a single session of acute intermittent hypoxia (AIH) on upper extremity motor function in healthy individuals in order to understand the mechanisms of AIH-induced plasticity.

Who is the study for?

This trial is for healthy individuals aged 18-70 with no history of cardiovascular issues, stroke, neurologic injuries, or severe neuromuscular disorders. Participants should not be on spasticity medications, smokers, have sleep apnea, or be pregnant. They must also not have metal implants that affect MRI scans.Check my eligibility

What is being tested?

The study tests the effects of a single session of Acute Intermittent Hypoxia (AIH) on arm function in healthy people compared to a sham procedure. It aims to understand AIH's role in inducing changes and potential benefits without underlying health conditions.See study design

What are the potential side effects?

While specific side effects are not listed for healthy subjects undergoing AIH, possible risks may include temporary shortness of breath, increased heart rate during hypoxia sessions and discomfort from wearing the breathing apparatus.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have no history of brain injuries or muscle diseases.

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I have a stable health condition with no heart or stroke issues.

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I am between 18 and 70 years old.

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I have never been diagnosed with sleep apnea.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ immediately after acute intermittent hypoxia administration

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~immediately after acute intermittent hypoxia administration

This trial's timeline: 3 weeks for screening, Varies for treatment, and immediately after acute intermittent hypoxia administration for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Grip Strength

Other outcome measures

Change in fMRI

Trial Design

2Treatment groups

Active Control

Placebo Group

Group I: Acute Intermittent Hypoxia (AIH)Active Control1 Intervention

Undergoing Acute Intermittent Hypoxia sessions

Group II: Sham AIHPlacebo Group1 Intervention

Undergoing Sham AIH sessions

0 / 4Eligibility criteria met

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Who is running the clinical trial?

Shirley Ryan AbilityLabLead Sponsor

192 Previous Clinical Trials

14,853 Total Patients Enrolled

William Rymer, PhDPrincipal InvestigatorShirley Ryan AbilityLab

Media Library

Acute Intermittent Hypoxia Clinical Trial Eligibility Overview. Trial Name: NCT04691518 — N/A

Healthy Subjects Research Study Groups: Acute Intermittent Hypoxia (AIH), Sham AIH

Healthy Subjects Clinical Trial 2023: Acute Intermittent Hypoxia Highlights & Side Effects. Trial Name: NCT04691518 — N/A

Acute Intermittent Hypoxia 2023 Treatment Timeline for Medical Study. Trial Name: NCT04691518 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this study actively seeking participants at this time?

"According to clinicaltrials.gov, this trial is no longer actively recruiting patients - the study was initially posted on November 16th 2016 and has not been updated since July 25th 2022. However, there are currently 1000 other trials that are welcoming participants at this time."

Answered by AI

Does this clinical trial encompass seniors aged 55 or above?

"This medical research is seeking participants aged 18 and up, with a maximum age of 70."

Answered by AI

Who meets the criteria to partake in this trial?

"This trial is seeking 32 individuals of ages 18 to 70 with anoxia as its primary inclusion criteria. Additionally, patients must have no prior history of neurological trauma or developing neuromuscular dysfunctions, be medically stable without a record of cardiac instability or stroke, not taking any medications related to spasticity in the past 2 weeks and also cannot be smokers nor possess sleep apnea. Last but not least they should demonstrate their ability to adhere to the protocol guidelines for this study."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Effect of Intermittent Hypoxia in Healthy Individuals

Zev Rymer 2016. "Effect of Intermittent Hypoxia in Healthy Individuals". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04691518.