IC Clinical Trials 2022

Browse 239 Ic Medical Studies Across 500 Cities

31 Phase 3 Trial · 1836 Ic Clinics

Clinical TrialsIC Clinical Trials 2022
Reviewed by Michael Gill, B. Sc.
Phase-Based Progress Estimates
1
Effectiveness
1
Safety

Pravastatinfor Hematopoietic stem cells

Cincinnati, OH
< 65
All Sexes
Chemotherapy and radiation used in patients undergoing bone marrow transplant (BMT) disrupts the endothelial lining (a thin layer of cells inside the blood vessels) which is found all throughout the body including the kidney, heart, lungs, and intestines. Disruption of this endothelial lining can lead to complications such as graft-vs-host disease (GVHD), thrombotic microangiopathy (TMA) and veno-occlusive disease (VOD). The purpose of this research study is to help investigators see if pravastatin is safe and well tolerated in patients undergoing BMT to see if it will reduce endothelial injury after BMT. The investigator hypothesizes that prophylactic pravastatin in pediatric allogeneic hematopoietic stem cell transplant recipients with elevated BMI is safe and feasible.
Phase 1
Waitlist Available
Phase-Based Progress Estimates
1
Effectiveness
2
Safety

Semaglutidefor Diabetes Mellitus, Type 2

Birmingham, AL
18 - 65
All Sexes
This study compares how three doses of semaglutide work in participants with type 2 diabetes (T2D) and overweight who are taking metformin. The study will look mainly at how well participant's blood sugar and participant's body weight are controlled when they are taking the study medicine at different doses. Participants will either get semaglutide [2 milligrams (mg), 8 mg, or 16 mg] or semaglutide placebo (a dummy medicine). Participants will take the study medicine with an injection pen called NovoPen®4. The injection pen is a medical tool with a needle used to inject the study medicine under the skin. The study will last for about 52 weeks. Participants will have 13 clinic visits and 4 phone calls.
Phase 2
Recruiting
25 Ic Clinical Trials Near Me
Cincinnati, OH
Hamilton, Canada
Birmingham, AL
San Antonio, TX
More Trial Locations
An interactive map to display trial locations for Cincinnati Children's Hospital Medical Center, Hamilton General Hospital, Novo Nordisk Investigational Site, Worldwide Clinical Trials, and 147 more locations.
Most Popular References for Ic Clinical Trials
Frequency
Citation
140
Spitzer, Robert L., Kurt Kroenke, Janet B. W. Williams, and Bernd Löwe. 2006. “A Brief Measure for Assessing Generalized Anxiety Disorder”. Archives of Internal Medicine. American Medical Association (AMA). doi:10.1001/archinte.166.10.1092.
91
Eisenhauer, E.A., P. Therasse, J. Bogaerts, L.H. Schwartz, D. Sargent, R. Ford, J. Dancey, et al.. 2009. “New Response Evaluation Criteria in Solid Tumours: Revised RECIST Guideline (version 1.1)”. European Journal of Cancer. Elsevier BV. doi:10.1016/j.ejca.2008.10.026.
30
Rosen, C. Brown, J. Heiman, S. Leib, R.. 2000. “The Female Sexual Function Index (FSFI): A Multidimensional Self-report Instrument for the Assessment of Female Sexual Function”. Journal of Sex & Marital Therapy. Informa UK Limited. doi:10.1080/009262300278597.
26
Brahmer, Julie, Karen L. Reckamp, Paul Baas, Lucio Crinò, Wilfried E.E. Eberhardt, Elena Poddubskaya, Scott Antonia, et al.. 2015. “Nivolumab Versus Docetaxel in Advanced Squamous-cell Non–small-cell Lung Cancer”. New England Journal of Medicine. Massachusetts Medical Society. doi:10.1056/nejmoa1504627.
24
Imamura M, Scott NW, Wallace SA, Ogah JA, Ford AA, Dubos YA, Brazzelli M. Interventions for treating people with symptoms of bladder pain syndrome: a network meta-analysis. Cochrane Database Syst Rev. 2020 Jul 30;7:CD013325. doi: 10.1002/14651858.CD013325.pub2.
22
Shi, Zheng, Yiqian Zhu, Jing Zhang, and Baoan Chen. 2022. “Monoclonal Antibodies: New Chance in the Management of B-cell Acute Lymphoblastic Leukemia”. Hematology. Informa UK Limited. doi:10.1080/16078454.2022.2074704.
22
Shi, Zheng, Yiqian Zhu, Jing Zhang, and Baoan Chen. 2022. “Monoclonal Antibodies: New Chance in the Management of B-cell Acute Lymphoblastic Leukemia”. Hematology. Informa UK Limited. doi:10.1080/16078454.2022.2074704.
21
Gerbershagen, Hans J., Sanjay Aduckathil, Albert J. M. van Wijck, Linda M. Peelen, Cor J. Kalkman, and Winfried Meissner. 2013. “Pain Intensity on the First Day After Surgery”. Anesthesiology. Ovid Technologies (Wolters Kluwer Health). doi:10.1097/aln.0b013e31828866b3.
20
Wolchok, Jedd D., Axel Hoos, Steven O'Day, Jeffrey S. Weber, Omid Hamid, Celeste Lebbé, Michele Maio, et al.. 2009. “Guidelines for the Evaluation of Immune Therapy Activity in Solid Tumors: Immune-related Response Criteria”. Clinical Cancer Research. American Association for Cancer Research (AACR). doi:10.1158/1078-0432.ccr-09-1624.
19
Blevins, Christy A., Frank W. Weathers, Margaret T. Davis, Tracy K. Witte, and Jessica L. Domino. 2015. “The Posttraumatic Stress Disorder Checklist for dsm-5 (PCL-5): Development and Initial Psychometric Evaluation”. Journal of Traumatic Stress. Wiley. doi:10.1002/jts.22059.
Top Hospitals for Ic Clinical Trials
Location
Active Ic Clinical Trials
All Time Trials for Ic
First Recorded Ic Trial
Trials
Massachusetts General Hospital, Boston, Massachusetts
15
15
2015
AccuCinch Ventricular Restoration System for Heart Failure
, Vorasidenib for Glioma
, Ivosidenib for Cancer ... View More
Washington University School of Medicine, Saint Louis, Missouri
10
10
2006
Post-Surgical Group for Parkinson Disease
, Sorafenib Tosylate for Multiple Endocrine Neoplasia Type 2B
, CFT8634 for Synovial Sarcoma ... View More
Dana-Farber Cancer Institute, Boston, Massachusetts
9
9
2017
Irinotecan for Small Cell Lung Carcinoma
, Vorasidenib for Glioma
, Berzosertib for Prostate Cancer ... View More
Memorial Sloan Kettering Cancer Center, New York, New York
9
9
2012
Vorasidenib for Glioma
, Regorafenib for Carcinoma, Adenoid Cystic
, Tacrolimus for Malignancies, Hematologic ... View More
Duke University Medical Center, Durham, North Carolina
8
8
2006
Liposomal Cyclosporine A for Bronchiolitis Obliterans
, Vorasidenib for Glioma
, Liposomal Cyclosporine A for Bronchiolitis Obliterans ... View More
Top Treatments for Ic Clinical Trials
Treatment Name
Active Ic Clinical Trials
All Time Trials for Ic
First Recorded Ic Trial
Trials
Pembrolizumab
4
4
2018
Pembrolizumab for Carcinoma, Non-Small-Cell Lung
, Pembrolizumab for Carcinoma, Non-Small-Cell Lung
, Pembrolizumab for Minimal Residual Disease ... View More
Liposomal Cyclosporine A
2
2
2019
Liposomal Cyclosporine A for Bronchiolitis Obliterans
, Liposomal Cyclosporine A for Bronchiolitis Obliterans
Vorinostat
2
2
2012
Vorinostat for Myelodysplastic Syndromes
, Vorinostat for Ulnar-mammary syndrome
Berzosertib
2
2
2018
Berzosertib for Solid Tumors, Advanced Solid Tumors
, Berzosertib for Prostate Cancer
Ipilimumab
2
2
2012
Ipilimumab for Human Papillomavirus Infections
, Ipilimumab for Cancer
Top Cities for Ic Clinical Trials
City
Active Ic Clinical Trials
Top Active Site for Ic Clinical Trials
Trial List
Boston, Massachusetts
52
Massachusetts General Hospital
Irinotecan for Small Cell Lung Carcinoma
, Altreno for Acne
, AccuCinch Ventricular Restoration System for Heart Failure ... View More
New York, New York
52
Memorial Sloan Kettering Cancer Center
Liposomal Cyclosporine A for Bronchiolitis Obliterans
, AccuCinch Ventricular Restoration System for Heart Failure
, AccuCinch Ventricular Restoration System for Heart Failure ... View More
Houston, Texas
41
M D Anderson Cancer Center
Venetoclax for Refractory B Acute Lymphoblastic Leukemia
, Liposomal Cyclosporine A for Bronchiolitis Obliterans
, Pharmacological Study for Metastatic Malignant Solid Neoplasm ... View More
Toronto, Ontario
35
Sunnybrook Health Sciences Centre
Withania somnifera for Lateral Sclerosis
, Vorasidenib for Glioma
, Vorasidenib for Glioma ... View More
Philadelphia, Pennsylvania
30
Thomas Jefferson University
ERICA for Cystitis, Interstitial
, Liposomal Cyclosporine A for Bronchiolitis Obliterans
, AccuCinch Ventricular Restoration System for Heart Failure ... View More
Which phases are most popular for ic clinical trials?
Phase
Active Ic Clinical Trials
Number of Unique Treatments
Number of Active Locations
Trial List
Phase < 1
5
5
4
Proflavine for Uterine Cervical Neoplasms
, vancomycin-tobramycin-itraconazole for Foot Ulcer
, Ustekinumab for Xeroderma ... View More
Phase 1
29
28
96
Pravastatin for Hematopoietic stem cells
, DS-2325a for Netherton Syndrome
, MYK-224 for Healthy Subjects (HS) ... View More
Phase 1 & 2
26
26
202
Venetoclax for Refractory B Acute Lymphoblastic Leukemia
, Fosciclopirox for Leukemia
, Cemiplimab for Cancer ... View More
Phase 2
55
53
353
Semaglutide for Diabetes Mellitus, Type 2
, Centanafadine for Smoking, Cessation
, Pelvic Floor Physical Therapy for Cystitis, Interstitial ... View More
Phase 2 & 3
3
3
4
EffCaMgCit for Chronic Kidney Diseases
, QRX003-4% Lotion for Netherton Syndrome
, NMES for Wounds
Phase 3
28
27
431
Irinotecan for Small Cell Lung Carcinoma
, Magnetic Resonance Imaging for Small cell carcinoma of lung
, Liposomal Cyclosporine A for Bronchiolitis Obliterans ... View More
Phase 4
8
8
44
Tissue Plasminogen Activator for Hematoma, Subdural
, Altreno for Acne
, Ertugliflozin 5 mg for Diabetes Mellitus, Type 2 ... View More
N/A
85
85
232
ERICA for Cystitis, Interstitial
, Citrate Dialysate for Vascular Calcification
, Post-Surgical Group for Parkinson Disease ... View More
How many ic clinical trials are open to youth and / or seniors?
Age Group
Active Ic Clinical Trials
Trial List
< 18
7
BB-12 with LGG (Lower Dose) for Autism Spectrum Disorder
, Early Diagnostic Response Model (EDRM) for Autism, Early Infantile
, office-based vergence/accommodative therapy for Opsoclonus ... View More
18+
183
Tissue Plasminogen Activator for Hematoma, Subdural
, ERICA for Cystitis, Interstitial
, Irinotecan for Small Cell Lung Carcinoma ... View More
18 - 65
18
Semaglutide for Diabetes Mellitus, Type 2
, DS-2325a for Netherton Syndrome
, MYK-224 for Healthy Subjects (HS) ... View More
< 65
8
Pravastatin for Hematopoietic stem cells
, Soticlestat for Epilepsies, Myoclonic
, Patients will be randomized into one of two study arms: (1) concomitant ACL and ALL reconstruction or (2) ACL reconstruction alone. for Anterior Cruciate Ligament Tear ... View More
65+
3
Eligard 22.5Mg Suspension for Injection for Alzheimer Disease
, Intervention Group for Coronary Artery Disease
, Diabetes Regulation for Eyesight and Memory for Cognitive Decline
Any Age
20
Acellular Cadaveric Dermal Matrix for Hernia
, CBT-001 for Pterygium
, Vorasidenib for Glioma ... View More
Most Recent Ic Clinical Trials
Clinical Trial
Began Recruiting Date
Phase
Cemiplimab for Cancer
9/29/2022
Phase 1 & 2
ECT device set to stimularte at a dose estimated to be below seizure threshold for Manic Disorder
9/28/2022
N/A
Pravastatin for Hematopoietic stem cells
9/1/2022
Phase 1
Tissue Plasminogen Activator for Hematoma, Subdural
9/1/2022
Phase 4
Photon counting computed tomography (PC-CT) for Coronary Artery Disease
9/1/2022
N/A
Phase 3 Ic Clinical Trials
Clinical Trial
Began Recruiting Date
Phase
Irinotecan for Small Cell Lung Carcinoma
7/22/2022
Phase 3
CBT-001 for Pterygium
6/30/2022
Phase 3
QRX003-4% Lotion for Netherton Syndrome
6/23/2022
Phase 2 & 3
AR 15512 Ophthalmic Solution for Eye Diseases
5/9/2022
Phase 3
contezolid acefosamil (IV)/contezolid (PO) for Communicable Diseases
5/1/2022
Phase 3
Pediatric Ic Clinical Trials
Clinical Trial
Began Recruiting Date
Phase
Pravastatin for Hematopoietic stem cells
9/1/2022
Phase 1
Tisagenlecleucel for B-Lymphocytes
7/12/2022
Phase 2
CBT-001 for Pterygium
6/30/2022
Phase 3
Early Diagnostic Response Model (EDRM) for Autism, Early Infantile
6/16/2022
N/A
Mood Education App for Depression
6/10/2022
N/A
Senior Friendly Ic Clinical Trials
Clinical Trial
Began Recruiting Date
Phase
Cemiplimab for Cancer
9/29/2022
Phase 1 & 2
Tissue Plasminogen Activator for Hematoma, Subdural
9/1/2022
Phase 4
Photon counting computed tomography (PC-CT) for Coronary Artery Disease
9/1/2022
N/A
Guidelines for Exercise in Multiple Sclerosis (GEMS) for Multiple Sclerosis
9/1/2022
N/A
MK-6194 for Eczema, Infantile
8/8/2022
Phase 1

About The Author

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 6th, 2021

Last Reviewed: August 19th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

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