This trial is testing if trabectedin and irinotecan can treat Ewing's sarcoma that has a EWS-FLI1 mutation. Patients will get an infusion of 18F-FLT and have a PET scan to see if the treatment is working.
- Ewing Sarcoma
1 Primary · 3 Secondary · Reporting Duration: up to 5 years
Side Effects for
Awards & Highlights
1 Treatment Group
Trabectedin and Irinotecan
1 of 1
48 Total Participants · 1 Treatment Group
Primary Treatment: Irinotecan · No Placebo Group · Phase 1 & 2
Who is running the clinical trial?
Age 6 - 99 · All Participants · 1 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Frequently Asked Questions
Does this research accommodate geriatric participants?
"This clinical trial seeks participants ranging in age from 10 to 99 years old. Additionally, there are 210 studies specifically for minors and 614 studies dedicated towards patients 65 and older." - Anonymous Online Contributor
In what common medical scenarios is Irinotecan deployed?
"The main therapy used to treat rna-binding protein fus is Irinotecan. Furthermore, this medication has been successful in treating colorectal carcinoma, ovarian cancer, and sarcoma as well." - Anonymous Online Contributor
Could you provide a summary of the research conducted on Irinotecan?
"In 2002, irinotecan was initially explored at Mayo Clinic in Rochester. Subsequently, 556 clinical trials were concluded with the drug and there are still 278 active research projects - many of them based out of Bethesda, Maryland." - Anonymous Online Contributor
Is this research experiment currently welcoming participants?
"Yes, according to clinicaltrials.gov this medical trial is presently searching for 45 subjects at 6 sites. It was initially posted on May 1st 2021 and its information has been most recently updated on August 15th 2022." - Anonymous Online Contributor
Which demographics are being considered for this clinical experiment?
"This medical trial is open to individuals between the ages of 10 and 99 who have been diagnosed with ewing sarcoma. Approximately 45 participants are being sought for this project." - Anonymous Online Contributor
Are there numerous locations where this experimental research is taking place within the city limits?
"Currently, 6 clinical trial sites are accepting participants for this study located in Bethesda, Boston, Los Angeles and several other cities. To best accommodate your needs it is advised that you choose the closest institution to minimize travel costs." - Anonymous Online Contributor
Has the FDA sanctioned Irinotecan for usage?
"Irinotecan's safety has only been assessed in minimal capacity, so it was assigned a rating of 1 on our scale from 1 to 3." - Anonymous Online Contributor
How many individuals have volunteered to take part in this scientific experiment?
"Yes, according to clinicaltrials.gov the research initiative is presently recruiting participants after being initially posted on May 1st 2021 and last updated on August 15th 2022. 45 study volunteers are needed from 6 different centres." - Anonymous Online Contributor