18F-DOPA with furosemide for Neuroendocrine Tumors

University of Alberta Hospital, Edmonton, Canada
Neuroendocrine Tumors18F-DOPA with furosemide - DiagnosticTest
All Sexes
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Study Summary

This trial is testing three different ways to detect neuroendocrine tumors, to see which is most effective.

Treatment Effectiveness

Phase-Based Effectiveness

1 of 3
Phase 2

Study Objectives

1 Primary · 3 Secondary · Reporting Duration: 12 months after completion of the 68Ga-HA-DOTATATE, 18F-FDG, and investigational 18F-DOPA PET/CT scans

Month 12
Assessment of disease progression - 12 months
Month 18
Assessment of disease progression - 18 months
Year 1
Lesion-to-lesion comparison of activity on 68Ga-HA-DOTATATE, 18F-DOPA, and 18F-FDG PET/CT scans
SUV of lesions on 68Ga-HA-DOTATATE, 18F-DOPA, and 18F-FDG PET/CT scans

Trial Safety

Phase-Based Safety

2 of 3
This is further along than 68% of similar trials

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

1 Treatment Group

18F-DOPA PET/CT scan
1 of 1

Experimental Treatment

50 Total Participants · 1 Treatment Group

Primary Treatment: 18F-DOPA with furosemide · No Placebo Group · Phase 2

18F-DOPA PET/CT scan
Experimental Group · 1 Intervention: 18F-DOPA with furosemide · Intervention Types: DiagnosticTest

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 12 months after completion of the 68ga-ha-dotatate, 18f-fdg, and investigational 18f-dopa pet/ct scans

Who is running the clinical trial?

University of AlbertaLead Sponsor
838 Previous Clinical Trials
386,690 Total Patients Enrolled
3 Trials studying Neuroendocrine Tumors
1,800 Patients Enrolled for Neuroendocrine Tumors
Jonathan AbelePrincipal InvestigatorUniversity of Alberta

Eligibility Criteria

Age 18+ · All Participants · 0 Total Inclusion Criteria

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Frequently Asked Questions

Is the recruitment phase of this research still open?

"Right, the latest information from clinicaltrials.gov confirms that this experiment is currently searching for participants to join. It was first advertised on October 15th 2022 and was recently modified on November 16th 2022. This trial seeks 50 patients at a single facility." - Anonymous Online Contributor

Unverified Answer

What potential risks could arise from administering 18F-DOPA with furosemide to individuals?

"After carefully evaluating the Phase 2 trial data, our team at Power determined that 18F-DOPA with furosemide is safe and gave it a rating of 2." - Anonymous Online Contributor

Unverified Answer

How many volunteers are involved in this medical experiment?

"Affirmative. The clinical trial information displayed on clinicaltrials.gov confirms that this medical study, which was initially posted on October 15th 2022, is actively recruiting patients. Around 50 individuals need to be enlisted from a single centre." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.