Speech Sound Stimulation for Language Disorder
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores how the brain processes speech sounds, with a focus on Heschl's gyrus. Researchers aim to understand how this area aids in speech comprehension by studying individuals who have undergone surgery on this part of the brain. The trial employs speech sound stimulation (also known as speech sound therapy or auditory feedback therapy) to collect data. It seeks English speakers aged 13-25 who have had surgery involving Heschl's gyrus and possess normal hearing and vision. As an unphased trial, this study provides a unique opportunity to contribute to groundbreaking research on speech processing in the brain.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
What prior data suggests that this speech sound stimulation is safe?
Research shows that using sound to address speech and language problems is generally safe. Studies have found that these treatments can enhance language skills in children without causing harm. Strong evidence of serious negative side effects from this type of treatment is lacking.
Typically, treatments for speech problems are manageable, often involving simple activities like sound exercises or therapy sessions. Since this trial uses sound to aid speech, past research suggests it is likely safe. However, staying informed and discussing any concerns with the study team is always advisable.12345Why are researchers excited about this trial?
Speech sound stimulation is unique because it targets language disorders by directly activating the brain's auditory processing area, specifically Heschl's gyrus. Unlike traditional speech therapy, which often relies on repetitive practice and behavioral techniques, this approach leverages neural mechanisms to enhance language processing. Researchers are excited about this technique because it could offer a more efficient and potentially faster way to improve language skills, particularly for individuals who have undergone neurosurgery in this critical brain region.
What evidence suggests that speech sound stimulation is effective for language disorder?
Research shows that assisting children with speech sounds can enhance their speech and language skills. Studies have found that children who struggle with speech sounds often face difficulties with reading and writing later, emphasizing the importance of early intervention. This trial will focus on speech sound stimulation to improve the skills necessary for clear speech. Additionally, combined treatment programs for speech sound issues have successfully improved speech clarity and understanding, which are crucial for effective communication. These findings suggest that speech sound stimulation benefits individuals with language disorders.678910
Who Is on the Research Team?
Taylor Abel, MD
Principal Investigator
University of Pittsburgh
Are You a Good Fit for This Trial?
This trial is for individuals aged 13-25 with normal nonverbal IQ, vision, language skills, and hearing. They must be monolingual English speakers undergoing surgery for a lesion in Heschl's gyrus without autism or ADHD history.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
sEEG-EEG Recording Sessions
Participants undergo sEEG-EEG recording sessions to measure pitch decoding accuracy, frequency-following response magnitude, and phase-locking limits
Follow-up
Participants are monitored for predictability effects of cortical resection on pitch decoding accuracy and frequency-following response magnitude
What Are the Treatments Tested in This Trial?
Interventions
- Speech sound stimulation
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Pittsburgh
Lead Sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
Collaborator