Diabetes Clinical Trials 2022

Diabetes studies recruiting patients for novel treatments. Filter by phase, distance, and inclusion criteria to find your perfect diabetes clinical trial in 2022.

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Medically Tailored Meals

This study is evaluating whether a medically tailored meal delivery program can help reduce high blood sugar after delivery of a baby.

This study is evaluating whether more aggressive glycemic targets for pregnant women with diabetes may improve outcomes.

Dexcom G6 Professional Continuous Glucose Monitor

This study is evaluating whether a set of activities can improve sleep habits in people with dementia.

This is a program evaluation that will evaluate the effectiveness of Mastering Diabetes, a therapeutic lifestyle change (TLC) program to control prediabetes and type 2 diabetes. Lifestyle change, focused on dietary change, physical activity, stress management and control of unhealthy subs…

Physical Activity Intervention

This study is evaluating whether a physical activity intervention can improve physical activity levels, maternal glycemic profile, and infant anthropometric measurements.

Mesenchymal Stem Cells (MSCs)

This study is evaluating whether a new treatment for type 1 diabetes may be effective.

This study is evaluating whether a nutrition program can reduce gestational diabetes in women of South Asian ancestry.

This study is evaluating whether diabetes and glycemia are related to brain tau accumulation.

This study is evaluating whether a reminder system can improve postpartum screening for diabetes in women with gestational diabetes mellitus (GDM).

Alert-based computerized decision support

While data from the National Health and Nutrition Examination Survey (NHANES) estimate that 36.9% of patients with diabetes have CKD, only approximately 10% of patients are aware of their kidney disease. In its 2020 Standards of Medical Care in Diabetes, the ADA recommends that all patient…

N-Acetylcysteine (NAC), an anti-oxidant, will be studied to investigate the effects on brain glutathione levels, cognitive skills, motor skills, and quality of life. A group of 18 patients will take either 1800, 3600 or 5400 mg per day of NAC (for 3 months) for a dose escalation study; th…

Telemedicine-Delivered Cognitive Behavioral Therapy

This study is evaluating whether a telemedicine-delivered cognitive-behavioral therapy program can improve diabetes distress and glycemic control in young adults with type 1 diabetes.

An Open-Label Part is added: This part will enroll in selected sites which are less affected by the COVID-19 pandemic. 150 subjects with NASH and fibrosis confirmed by liver histology (F1-F3) will be randomized into 3 groups according to the post-baseline biopsy. The objective of the Op…

Diabetes costs the U.S. healthcare system more than any other disease, and nearly half of Americans will develop either diabetes or prediabetes in their lifetime. It is therefore critical to find new strategies to treat or reverse diabetes. One such approach is adopting a healthy diet, wh…

This study is evaluating whether aerobic or yoga training can improve insulin resistance in people with obesity.

This study is evaluating whether participation in an Internet-based intervention helps improve medication use.

Lifestyle Weight Loss Intervention

This study is evaluating whether bariatric surgery is more effective than a lifestyle intervention in inducing weight loss in people with diabetes.

Older adults with type 2 diabetes experience neurocognitive decline and are at higher risk for developing dementia. Consequently, older adults at-risk for developing type 2 diabetes (i.e., those who are overweight and/or prediabetic) are at higher risk for neurocognitive decline, and inter…

This study is evaluating whether a drug may help treat diabetic macular edema.

This study is evaluating whether resveratrol may have positive impacts for individuals with type 1 diabetes.

Excess weight, nutrition, and blood sugar levels can all affect immune function, which in turn can affect participants risk for heart disease and type 2 diabetes (T2DM). It is not known how diet, blood sugar, and weight affect immune function. The purpose of the study is to look at how we…

Blackmores Omega Daily (4 1g capsules per day)

This study is evaluating whether changes in cornea sensitivity may be a useful tool for diagnosing peripheral neuropathy.

Motivational Enhancement System (MES)

This study is evaluating whether a multi-component behavioral intervention can help improve metabolic control among older adolescents and emerging adults with type 1 diabetes.

Calcium Oxalate Kidney Stone Formers

This study is evaluating whether obesity is a risk factor for kidney stones.

This study is evaluating whether a medication called diazoxide can help control glucose levels in people with type 2 diabetes.

Diabetes MESSAGES Program

This study is evaluating whether a diabetes group visit program can improve diabetes care and health care utilization.

To determine if levodopa will slow the appearance of blood vessel changes in the eyes of patients with diabetes. Treatment will be started in patients with diabetes show delays in the electrical activity of the retina when measured non-invasively with a electroretinogram.

conjugated estrogens/bazedoxifene (CE/BZA)

This study is evaluating whether a novel menopause hormone therapy can improve blood sugar and blood and liver fats in obese menopausal women.

This study is evaluating whether a new type of diabetes and hypertension self-management program is feasible and acceptable for individuals with these conditions.

This study is evaluating whether a drug may help treat diabetic retinopathy and macular edema.

This study is evaluating whether a drug used to treat overactive bladder may also help improve glucose tolerance and fat levels in individuals with prediabetes.

Rural Diabetes One-Day Education and Care program (R-D1D)

This study is evaluating whether a telehealth intervention can help improve diabetes management for rural populations.

MAINTAIN PRIME Lifestyle Coaching

Many people struggle not only to lose weight through changes in diet and physical activity, but also to maintain weight loss once they have achieved it. In a previous study, our team designed and deployed a weight maintenance intervention that was delivered through the patient portal of an…

This study is evaluating whether a drug that blocks immune cells can help prevent the loss of insulin-producing cells in people with type 1 diabetes.

The Complete Health Improvement Program

This study is evaluating whether a program which helps individuals with chronic disease can help improve their health.

Mobile health application

The purpose of this study is to determine the effectiveness of mobile health applications in improving health outcomes and the subsequent benefit of improving type II diabetes outcomes in a low socioeconomic Hispanic population. This study will involve a 6-month long commitment where parti…

Fish Oil Concentrate, 1000 Mg Oral Capsule

Diabetic peripheral neuropathy (DPN) is the most common chronic complication of diabetes, affecting about 50% of patients with diabetes and leading to severe morbidity, poor quality of life, high mortality, and high health care costs. Due to the complex structure and anatomy of the periphe…

Carbohydrate-First Meal Sequence

This study is evaluating whether the order in which food is consumed can impact blood sugar levels in individuals with type 2 diabetes.

Financial incentive (loss)

This study is evaluating whether financial incentives can help motivate adolescents with type 1 diabetes to improve their self-care.

Staff -Educational training

This study addresses education needs in gestational diabetes care and followup at the staff and patient levels. In the initial phase, nurses and community health workers will complete specific training modules on gestational diabetes developed for this study. The effectiveness of the educ…

Lactiplantibacillus plantarum

This study is evaluating whether a probiotic may help reduce inflammation and improve insulin production in individuals with type 1 diabetes.

This study is evaluating whether a portable device can accurately measure blood sugar levels.

Portfolio diet and structured exercise

This study is evaluating whether a dietary portfolio of cholesterol-lowering foods (viscous fibres, soy protein, plant sterols and nuts) further enhanced by increased levels of monounsaturated fatty acids (MUFA) and low glycemic index foods; together with a structured exercise program redu…

30-minute walking intervention

The aim of this study is to understand if the timing of exercise around food intake can help improve blood sugar management in pregnant individuals with diabetes.

Continuous Glucose Monitor (CGM)

This study is evaluating whether continuous glucose monitors are accurate for blood glucose monitoring.

VC-01 Combination Product

This study is evaluating whether a combination of stem cells and a drug may help cure type 1 diabetes.

Diabetes self-management education

This study is evaluating whether a flash glucose monitor device can help people with type 2 diabetes control their blood sugar.

This study is evaluating whether semaglutide may help improve walking ability in individuals with peripheral arterial disease and type 2 diabetes.

14-day outpatient intervention

A closed-loop insulin system, also referred to as the "artificial pancreas" (AP), is made up of an insulin pump, a continuous glucose monitor, and an application communicating between the two to adjust insulin administration based on glucose control. This is meant for the treatment of type…

SUPPORT online platform for people with type 1 diabetes

This study is evaluating whether a web-based training and support program can reduce the frequency of hypoglycemia in people with type 1 diabetes.

This study is evaluating whether exercise may help improve glucose and lipid levels in pregnant women with gestational diabetes.

This study is evaluating whether a wearable bionic pancreas system can help regulate blood sugar levels for individuals with cystic fibrosis.

Twin Precision Treatment

This is a randomized study comparing outcomes of patients diagnosed with Type 2 Diabetes (T2D) who are enrolled into the Twin Health Precision Treatment (TPT) system versus usual care. The study will last for a year with a 1 year optional extension for the TPT arm patients to continue for …

Sensor augmented MDI therapy plus mobile application

This study is evaluating whether a mobile application can help people with type 1 diabetes manage their insulin and exercise better.

This study is evaluating whether a yoga program is as effective as a standard exercise program for people with type 2 diabetes.

This study compares insulin icodec (a new insulin) to insulin degludec (an insulin already available on the market) in people with type 1 diabetes. The study will look at how well insulin icodec taken weekly controls blood sugar compared to insulin degludec taken daily. Participants will…

Faith-Based (FB, BHT DSMS)

The present study proposes to test the effectiveness of the Building a Healthy Temple: Diabetes Self-Management Support Program (BHT DSMS), a rendition of the Stanford DSMP in a spiritual context for the Hispanic faith community members. Using a holistic approach through integrating spirit…

Diabetes has recently been referred to as "the epidemic of the 21st century". The reason why women with type 1 diabetes have a 2-3 fold greater risk of cardiovascular disease (CVD) compared to men with type 1 diabetes is unknown.The purpose of this study is to investigate whether or not es…

The study's goal is to promote accessible and cost-effective diabetes care through electronic means. Underserved populations including rural areas do not have diabetes specialists. Previous study data has shown the effectiveness of Internet communication in lowering a patient's Hemoglobin …

Percutaneous Coronary Intervention

The purpose of this study is to compare 5-year mortality rates in diabetic individuals with multivessel coronary artery disease (CAD) who undergo either coronary artery bypass grafting (CABG) surgery or percutaneous coronary stenting.

Diabetes Prevention Program

African Americans (AAs) have rates of diabetes mellitus (DM) twice that of Whites and are disproportionately affected by leading risk factors for DM - obesity and low-income. A critical strategy in the battle against DM is the Diabetes Prevention Program (DPP), an evidence-based interventi…

Daily calorie restriction

Innovative lifestyle strategies to treat type 2 diabetes (T2DM) are critically needed. "Time restricted feeding" (TRF), and involves confining the period of food intake to 6-8 h per day. TRF allows individuals to self-select foods and eat ad libitum during a large part of the day, which gr…

This study is evaluating whether a new medicine called cagrilintide works better with semaglutide than cagrilintide alone or semaglutide alone.

CI-PVP (context-informed pre-visit planning)

This study is evaluating whether a pre-visit planning intervention can reduce the burden of diabetes care on patients without increasing the visit workload.

This study is evaluating whether diet beverages may have negative impacts for individuals with diabetes.

Fresh organic vegetables

Farming for Life aims to determine the health impacts of providing weekly "prescriptions" of fresh organic vegetables to adults living with or at risk of type 2 diabetes. Over 4 years, up to 400 adults diagnosed with or at high risk of developing type 2 diabetes will be engaged for 3 month…

Basic needs navigation

This study is evaluating whether a navigation program can help people with diabetes control their blood sugar.

Protocol-based integrated care

This study is evaluating whether a set of activities can improve blood sugar levels in people with diabetes.

Application Validation

The Validation of the Diabetes Deep Neural Network Score (DNN score) for Screening for Type 2 Diabetes Mellitus (diabetes) is a single center, unblinded, observational study to clinically validating a previously developed remote digital biomarker, identified as the DNN score, to screen for…

This study is evaluating whether a gene expression profile can predict how people respond to a drug.

High-intensity interval training (HIIT)-4

This study is evaluating whether a high-intensity exercise program can improve blood pressure and arterial stiffness in people with type 2 diabetes.

This study is evaluating whether a surgery which reduces bloodflow in a stomach artery leads to significant weightloss.

This study is evaluating whether a high fat/protein breakfast may improve blood glucose control for women with gestational diabetes.

This is a pragmatic, 24 month, single-center, randomized, open-label, parallel-group trial comparing an obesity-centric approach with a medically-supervised and comprehensive weight loss program (Cleveland Clinic's Endocrinology and Metabolism Institute's Integrated Weight Management Progr…

This study is evaluating whether cinnamon capsules may help improve glucose tolerance in individuals who are overweight or obese.

Very Low Carbohydrate Diet

This study is evaluating whether a very low carbohydrate diet may help improve blood sugar levels in youth with type 1 diabetes.

Neuropsychological Consultation

This study is evaluating whether a neuropsychological consultation may help improve quality of life for children with diabetes.

This study will integrate a technology-based patient-reported outcome (PRO) system [herein MJS DIABETES] that incorporates patients' perspective of their disease and functional status into the management of type 2 diabetes (T2D) in primary care practices. MJS DIABETES is an innovative mobi…

This study is evaluating whether a device can help people with diabetes.

Glucagon Nasal Powder [Baqsimi]

This study is evaluating the safety and tolerability of a study drug called nasal glucagon in pediatric participants with type 1 diabetes.

This study is evaluating whether a package of implementation strategies can help primary care practices integrate medical and psychosocial care for patients with type 2 diabetes.

The primary objective of this study is to determine the mechanism of reduced branched-chain amino acid (BCAA) oxidation to propionyl CoA and isoleucine intake can affect TCA cycle function in obese insulin resistant T2D. We will test the hypotheses that isoleucine and valine oxidation to p…

This study compares insulin icodec (a new insulin taken once a week) to insulin glargine (an insulin taken once daily which is already available on the market) in people with type 2 diabetes. The study will look at how well insulin icodec taken weekly controls blood sugar compared to insu…