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Muscle Relaxant

Not pretreated for Muscle Pain

Phase 3
Waitlist Available
Led By Leighan Bye, MD
Research Sponsored by Indiana University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up immediately following succinylcholine administration
Awards & highlights

Study Summary

This trial is testing whether or not a second medication can reduce muscle soreness caused by the first medication given as part of anesthesia.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~24 hours post succinylcholine administration
This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 hours post succinylcholine administration for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Myalgia
Secondary outcome measures
Presence or absence of muscle fasciculation following succinylcholine administration

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Not pretreatedExperimental Treatment1 Intervention
Succinylcholine administration with no Rocuronium pre-treatment
Group II: Pre-treated 2 minutes before succinylcholine administratjionActive Control1 Intervention
Succinylcholine administratjion 2 minutes following Rocuronium pre-treatment
Group III: Pre-treated 1 minute before succinylcholine administrationActive Control1 Intervention
Succinylcholine administration 1 minute following Rocuronium pre-treatment

Find a Location

Who is running the clinical trial?

Indiana UniversityLead Sponsor
980 Previous Clinical Trials
982,861 Total Patients Enrolled
Leighan Bye, MDPrincipal InvestigatorIndiana University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are people still being signed up for participation in this research project?

"The clinical trial is currently looking for patients, as indicated by the information on clinicaltrials.gov. This trial was first posted on October 2nd, 2020 and was last updated on September 6th, 2022."

Answered by AI

What conditions is Pre-treated 2 minutes before succinylcholine administratjion commonly used to alleviate?

"The medical procedures of intubation, general anesthesia, and tracheal intubation can be facilitated by administering Pre-treatment 2 minutes before succinylcholine."

Answered by AI

Could I possibly enroll in this clinical trial?

"Eligibility requirements for this trial include myalgia and being between 18-100 years old. A total of 300 patients are needed for this study."

Answered by AI

Does this research project only consider young adults aged 25 and under?

"According to the eligibility requirements published for this trial, patients between the ages of 18 and 100 may participate. There are 10 separate trials for patients younger than 18 and 27 trials for patients that are 65 or older."

Answered by AI

How many individuals are included in the research being conducted?

"That is accurate. The information available on clinicaltrials.gov tells us that this clinical trial is looking for volunteers right now. The listing was first created on October 2nd, 2020 and was updated September 6th, 2022. They need 300 individuals total and are only testing at a single site."

Answered by AI

What other scientific investigations have there been of patients who were given a pre-treatment two minutes before being given succinylcholine?

"Currently, there are 16 clinical trials underway investigating the use of Pre-treated 2 minutes before succinylcholine administratjion. 3 of those trials are in Phase 3. The majority of trials for Pre-treated 2 minutes before succinylcholine administratjion are based in Montreal, Quebec, but there are 29 locations running studies for this treatment."

Answered by AI

What are the risks of Pre-treatment 2 minutes before succinylcholine administratjion?

"This study has reached Phase 3, meaning that there is both evidence of efficacy and multiple rounds of data supporting safety. As such, we have rated the safety of Pre-treated 2 minutes before succinylcholine administratjion as a 3."

Answered by AI

What is the precedence for this type of clinical testing?

"Pre-treatment with 2 minutes of administration of succinylcholine has been studied since 2009. The first study was sponsored by Medtronic - MITG and occurred in 80 patients. After the first trial, Pre-treatment with 2 minutes of administration of succinylcholine received N/A drug approval. There are 16 live trials today for Pre-treatment with 2 minutes of administration of succinylcholine across 11 cities and 10 countries."

Answered by AI
~67 spots leftby Apr 2025