← Back to Search

Opioid Analgesic

Rocuronium + Remifentanil for Surgical Anesthesia

N/A

Waitlist Available

Research Sponsored by St. Vincent's Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

No use of psychotropic or neuropsychiatric medications

Presence of ASA physical status class I or II (excluding subjects with significant medical problems)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 1-6 hours

Awards & highlights

Study Summary

This trial is designed to study the effects of different doses of the medication rocuronium on patients undergoing surgery with general anesthesia. Researchers will be monitoring patients' vital signs and levels of muscle relaxation throughout the surgery and afterwards to see how well the rocuronium works.

Who is the study for?

This trial is for healthy adults aged 18-75 who need general anesthesia for surgery. Participants should have a BMI of 18-35 and no significant medical issues (ASA status I or II). They must not be on psychotropic drugs, have an easy-to-intubate airway, and not take certain medications.Check my eligibility

What is being tested?

The study tests how different doses of rocuronium affect the body's response to laryngoscopy under anesthesia. Subjects will receive one of four doses of rocuronium plus remifentanil infusion at two possible levels during surgery, with their muscle relaxation and vital signs monitored.See study design

What are the potential side effects?

Possible side effects include typical anesthesia risks such as nausea, sore throat from intubation, pain after waking up which will be managed with morphine, and variations in blood pressure or heart rate during the procedure.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am not taking any medications for mental health issues.

Select...

I am generally healthy or have mild health issues.

Select...

I am between 18 and 75 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 1-6 hours

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~1-6 hours

This trial's timeline: 3 weeks for screening, Varies for treatment, and 1-6 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Variable response to medication given.

Trial Design

6Treatment groups

Experimental Treatment

Group I: Dose 3bExperimental Treatment1 Intervention

Group II: Dose 3aExperimental Treatment1 Intervention

Group III: Dose 2bExperimental Treatment1 Intervention

Group IV: Dose 2aExperimental Treatment1 Intervention

Group V: Dose 1bExperimental Treatment1 Intervention

Group VI: Dose 1aExperimental Treatment1 Intervention

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

St. Vincent's Medical CenterLead Sponsor

4 Previous Clinical Trials

493 Total Patients Enrolled

Medtronic - MITGIndustry Sponsor

252 Previous Clinical Trials

300,606 Total Patients Enrolled

Media Library

Remifentanil (Opioid Analgesic) Clinical Trial Eligibility Overview. Trial Name: NCT00926718 — N/A

Laryngoscopy Research Study Groups: Dose 1b, Dose 1a, Dose 2a, Dose 3a, Dose 3b, Dose 2b

Laryngoscopy Clinical Trial 2023: Remifentanil Highlights & Side Effects. Trial Name: NCT00926718 — N/A

Remifentanil (Opioid Analgesic) 2023 Treatment Timeline for Medical Study. Trial Name: NCT00926718 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many individuals have registered to participate in this research?

"This investigation is not currently accepting volunteers for participation. Initial posting and last editing occurred on June 1st 2009 and June 22nd 2009 respectively. If you are considering alternative studies, two medical trials that involve laryngoscopy as well as 36 investigations related to rocuronium dose + remifentanil infusion are presently recruiting patients."

Answered by AI

What is the most common application of a rocuronium dose combined with remifentanil infusion?

"Rocuronium dose and remifentanil infusion are conventionally employed to address muscle fasciculation. Moreover, they can be utilized in intubation (a surgical procedure), pain alleviation, and neuromuscular blocking therapy."

Answered by AI

Does this clinical trial offer a unique approach to treatment?

"Since its introduction in 2009, the study of rocuronium dose + remifentanil infusion has seen significant growth. Initially sponsored by Medtronic - MITG and involving 80 patients, it eventually gained N/A approval following successful results. Currently, there are 36 trials ongoing around 18 different countries with 46 cities represented collectively."

Answered by AI

Is access to this trial currently achievable for participants?

"Unfortunately, this research is no longer recruiting. The initial posting was on June 1st 2009 and the last update to clinicaltrials.gov occured on June 22nd of that same year. If you're interested in other studies, there are 2 active trials for laryngoscopy and 36 for rocuronium dose + remifentanil infusion currently accepting patients."

Answered by AI

Could you summarize the existing research on combining rocuronium dose with remifentanil infusion?

"At present, 36 clinical trials are exploring the efficacy of rocuronium dose + remifentanil infusion. Out of those, 8 have progressed to Phase 3. These studies are being conducted across 87 different locations with Seoul as the primary source for these experiments."

Answered by AI

To whom does this clinical trial appeal?

"This clinical trial is recruiting 80 volunteers, aged 18-75 with laryngoscopy who meet the criteria of having a BMI between 18 and 35 kg m-2., being ASA physical status class I or II (which precludes those with serious medical issues), not taking psychotropic/neuropsychiatric drugs, an airway assessment indicating no difficulty in intubation including Mandible-to-hyoid distance greater than three fingerbreadths and Malampatti Class I or II."

Answered by AI

Does this research experiment accept participants over forty years of age?

"This clinical trial is specifically looking for participants aged between 18 to 75. For minors and seniors, there are 8 trials available respectively."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

The Effect of Rocuronium on the Response of Composite Variability Index (CVI) to Laryngoscopy

2009. "The Effect of Rocuronium on the Response of Composite Variability Index (CVI) to Laryngoscopy". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00926718.

All > New York