Robot Therapy for Stroke

Not currently recruiting at 1 trial location
MJ
Overseen ByMichelle Johnson, PhD
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine if affordable robot therapy can help stroke survivors in Botswana, with or without HIV, improve their physical abilities. The focus is on using robot and mobile health technologies to make rehabilitation more accessible and cost-effective. The study seeks stroke survivors who can handle therapy and have moderate cognitive function. Participants should be at least three months post-stroke and medically stable.

As an unphased trial, this study offers a unique opportunity to contribute to innovative research that could enhance rehabilitation options for stroke survivors.

Will I have to stop taking my current medications?

The trial information does not specify if you need to stop taking your current medications. It is up to the physician to decide if a subject should be excluded due to taking medication that would impair cognitive ability.

What prior data suggests that this robot therapy is safe for stroke survivors?

Research shows that robot-assisted therapy is generally well-tolerated for stroke recovery. Studies have found that it helps patients improve movement after therapy. Although some studies suggest that robot therapy may not always surpass traditional rehab in effectiveness, it has not raised major safety concerns. This indicates that the therapy is unlikely to cause harm or serious side effects. Therefore, evidence suggests that this type of therapy is quite safe for participants considering joining a trial.12345

Why are researchers excited about this trial?

Robot Therapy for stroke recovery is unique because it leverages advanced robotic technology to aid in rehabilitation, offering precision and consistency that human therapists might not be able to achieve. Unlike traditional physical therapy, which relies heavily on manual exercises and therapist interaction, robot therapy can provide repetitive and targeted movements, which are crucial for neuroplasticity and motor recovery. Researchers are excited because this method has the potential to enhance the rehabilitation process, especially for stroke survivors with complex conditions like those with HIV/AIDS, by offering tailored therapy that adapts to individual patient needs and progress.

What evidence suggests that robot therapy is effective for stroke rehabilitation?

Research has shown that robotic therapy, which participants in this trial will receive, can help stroke patients improve movement abilities. One study found that therapy with robots led to better recovery of motor skills than traditional rehabilitation methods. Another study demonstrated that robotic therapy improved endurance, balance, and cognitive skills. Additionally, robotic training for the legs helped stroke patients walk better. While some studies suggest that the improvements might not be life-changing, the overall evidence indicates a moderate but important benefit from using robotic therapy.12567

Who Is on the Research Team?

MJ

Michelle J Johnson, PhD

Principal Investigator

University of Pennsylvania

Are You a Good Fit for This Trial?

This trial is for adults over 18 in Botswana who've had a stroke and are living with or without HIV. They should have moderate neurological function and cognitive ability, be medically stable to handle therapy, and able to consent. People with severe drug/alcohol abuse, depression, excessive pain, extreme spasticity or paralysis, psychiatric or cardiac issues, prior brain injury or open lesions can't join.

Inclusion Criteria

I had a stroke at least 3 months ago and am over 18.
Able to give consent
You need to have pretty good thinking and memory skills according to a specific test.
See 2 more

Exclusion Criteria

I am unable to understand and give consent for treatment.
You have severe depression according to a specific test called Becks Depression Inventory-Fast Screener.
I have total paralysis or cannot move my arms or legs due to stiffness.
See 6 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Optimization

Optimization of the robot system for the Botswana context, including cost-effectiveness and local resource utilization

Not specified

Treatment

Participants receive therapy using the robot gym system and standard of care

8 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Robot Therapy
Trial Overview The study is exploring the use of affordable robot-assisted rehabilitation combined with mobile health technologies for people in Botswana who have suffered a stroke associated with HIV. It aims to test if this approach is feasible and effective in improving their functional outcomes.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Group I: Stroke survivorsExperimental Treatment1 Intervention
Group II: Low-to-mid functioning HIV/AIDS patientsExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Pennsylvania

Lead Sponsor

Trials
2,118
Recruited
45,270,000+

Citations

Systematic review and meta-analysis of effectiveness of ...Robotic therapy showed a moderate but statistically significant effect over conventional rehabilitation (SMD = 0.59, 95% CI: [0.33; 0.84], p < ...
Effects of Robot-Assisted Therapy for Upper Limb ...The results of the study showed that robot-assisted therapy showed significant motor function recovery, both when compared with conventional ...
Upper limb robotic rehabilitation following stroke: a systematic ...The results suggest that robotic rehabilitation does not result in clinically meaningful improvement in either upper limb capacity or ADL performance.
The impact of robotic hand rehabilitation on hand function ...Many studies demonstrate the effectiveness of robotic-assisted therapy in improving endurance, balance, and cognitive function in stroke patients. Stroke ...
Effect of robot-assisted training for lower limb rehabilitation ...The study discovered that lower limb rehabilitation robot-assisted training considerably enhanced walking ability in stroke patients, with the difference being ...
Robotic Assisted Upper-Limb Neurorehabilitation in Stroke ...Study Abstract: CSP #558 will be a randomized, multi-center, outpatient phase II trial to assess the safety and efficacy of robot-assisted therapy for ...
Functional and motoric outcome of AI-assisted stroke ...The results showed that AI-assisted rehabilitation combined with robot utilization was not significantly better than conventional rehabilitation methods.
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