CO2 Laser for Vocal Cord Lesions

Overseen by Milan Amin, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: NYU Langone Health

No Placebo Group

Trial Summary

What is the purpose of this trial?

This trial compares a CO2 laser device (AcuPulse Duo) with a commonly used KTP laser for treating vocal lesions. The CO2 laser is precise and causes less deep tissue damage, leading to faster recovery. The KTP laser targets blood vessels but can cause more scarring. The KTP laser has been increasingly used over the past decade for office-based management of vocal fold lesions.

Research Team

Milan Amin, MD

Principal Investigator

NYU Langone Health

Eligibility Criteria

This trial is for individuals who can consent and have specific vocal cord issues like laryngeal papillomatosis, hemorrhagic polyps, or leukoplakia/dysplasia needing in-office treatment. It's not suitable for those with prolonged redness of the skin, a history of keloid scars, or recent Accutane use.

Inclusion Criteria

I have growths or changes in my vocal cords that need treatment in a doctor's office.

I am able to understand and agree to the study's procedures.

Exclusion Criteria

You have unusually long-lasting redness on your skin.

You have a history of forming keloids.

I have not taken Accutane in the last 6-12 months.

Treatment Details

Interventions

• AcuPulse Duo (CO2 Laser)

Trial Overview The study compares two lasers used to treat vocal cord lesions: the CO2 laser (AcuPulse Duo) and the commonly used Aura KTP laser. The goal is to see which device offers better results for treating these conditions.

Participant Groups

Group I: CO2 laser device group Experimental Treatment 1 Intervention

Participants who will be undergoing laser treatment for their vocal nodes with a specific laser device. AcuPulse Duo, a CO2 laser is absorbed by water found in soft tissues and is independent of tissue color. It is very precise and causes less damage of the deep tissues, which results in less swelling and faster recovery. The absence of a long healing process means that most patients can resume their normal activities even on the same day The CO2 laser is the preferred laser for use in the operating room.

Who Is Running the Clinical Trial?

NYU Langone Health

Lead Sponsor

Trials

1,431

Recruited

838,000+