Reviewed by Michael Gill, B. Sc.
Image of Massachusetts General Hospital in Boston, United States.
Phase-Based Progress Estimates
1
Effectiveness
1
Safety

Non-ablative Fractional Laser Plus Microneedlingfor Acne Scars

18+
All Sexes
Acne scarring is an unfortunate consequence of inflammatory acne vulgaris that often leads to significant cosmetic and psychosocial impacts. Although there have been many advances in the treatment of acne scarring, it remains one of the greatest challenges in cosmetic and laser dermatology. There have been a multitude of studies establishing the efficacy of non-ablative fractional laser therapy for the treatment of atrophic acne scars, and it is widely regarded as one of the best available treatments. More recently, there has been a renewed interest in controlled, non-thermal dermal injury via microneedling devices in the treatment of atrophic acne scars. Where there is a gap in the literature, however, is in the evaluation of the combination of non-ablative fractional laser resurfacing with microneedling in the treatment of atrophic acne scars. The investigators' study will compare the safety and efficacy of using non-ablative fractional laser versus a combination of microneedling and non-ablative fractional laser for atrophic acne scars using a randomized, double-blind, split-face study. The investigators' aim is to further elucidate the pathogenesis of acne scarring and the best approaches for treatment. In doing so, the investigators will study a combination approach to this complex problem in order to better serve future patients.
Waitlist Available
Has No Placebo
Massachusetts General HospitalMathew Avram, MD
9 Acne Scars Clinical Trials Near Me
Top Hospitals for Acne Scars Clinical Trials
Image of New York Laser & Skin Care in New York.
New York Laser & Skin Care
New York
2Active Trials
0All Time Trials for Acne Scars
2015First Acne Scars Trial
Image of Northwestern University Feinberg School of Medicine, Department of Dermatology in Illinois.
Northwestern University Feinberg School of Medicine, Department of Dermatology
Chicago
2Active Trials
0All Time Trials for Acne Scars
2012First Acne Scars Trial
Top Cities for Acne Scars Clinical Trials
Image of New York in New York.
New York
5Active Trials
New York Laser & Skin CareTop Active Site
Image of Chicago in Illinois.
Chicago
4Active Trials
Northwestern University Feinberg School of Medicine, Department of DermatologyTop Active Site
Acne Scars Clinical Trials by Phase of Trial
Most Recent Acne Scars Clinical Trials
Top Treatments for Acne Scars Clinical Trials
Treatment Name
Active Acne Scars Clinical Trials
All Time Trials for Acne Scars
First Recorded Acne Scars Trial
Sofwave
1
1
2022
PicoSure Pro Device
1
1
2021
Experimental: RF Device Arm
1
1
2021
Non-ablative Fractional Laser Plus Microneedling
1
1
2019
other
1
1
2017

About The Author

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 4th, 2021

Last Reviewed: November 1st, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

References1 Hoang Viet M, Derreumaux P, Li MS, Roland C, Sagui C, Nguyen PH. Picosecond dissociation of amyloid fibrils with infrared laser: A nonequilibrium simulation study. J Chem Phys. 2015 Oct 21;143(15):155101. doi: 10.1063/1.4933207. https://pubmed.ncbi.nlm.nih.gov/26493925