Osteosarcoma Clinical Trials 2022

Browse 76 Osteosarcoma Medical Studies Across 224 Cities
3 Phase 3 Trial · 2126 Osteosarcoma Clinics

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Clinical Trials Osteosarcoma Clinical Trials 2022

Reviewed by Michael Gill, B. Sc.

Image of Seattle Children's Hospital in Seattle, United States.

Phase-Based Progress Estimates

UB_TT170for Osteosarcoma

This trial is testing a new combination treatment for osteosarcoma that has not responded to other treatments or has returned after treatment.

Seattle Children's HospitalNavin Pinto, MD

Image of Children's National Hospital in Washington, United States.

Phase-Based Progress Estimates

Nivolumabfor Rhabdomyosarcoma

This trial is studying whether a combination of two immunotherapy drugs, nivolumab and ipilimumab, can help to shrink solid tumors in children and young adults.

Children's National HospitalMarie Nelson, MDBristol-Myers Squibb

Image of Children's Hospital of Alabama in Birmingham, United States.

Phase-Based Progress Estimates

Thoracoscopyfor Osteosarcoma

This trial compares the effect of open thoracic surgery to thoracoscopic surgery in treating patients with osteosarcoma that has spread to the lung.

Children's Hospital of Alabama (+99 Sites)John J Doski

Image of Site 0106 in Los Angeles, United States.

Phase-Based Progress Estimates

ZN-c3for Osteosarcoma

FDA Approved Drug

This trial is testing a new drug combination to treat osteosarcoma, a bone cancer.

FDA Approved Drug

Site 0106 (+11 Sites)K-Group Beta

Image of Children's Hospital of Los Angeles in Los Angeles, United States.

Phase-Based Progress Estimates

Nivolumabfor Osteosarcoma

FDA Approved Drug

This trial is testing a new combination therapy for people with a certain type of bone cancer that has returned or does not respond to treatment.

FDA Approved Drug

Children's Hospital of Los Angeles (+8 Sites)

Image of Seattle Children's Hospital in Seattle, United States.

Phase-Based Progress Estimates

Second Generation 4-1BBζ B7H3-EGFRt-DHFRfor Wilms Tumor

This trial is testing a new treatment for cancer that uses the patient's own immune cells that have been genetically modified to kill cancer cells. The goal is to find out if it is safe and works well.

Seattle Children's HospitalNavin Pinto, MD

Image of Dana Farber Cancer Institite in Boston, United States.

Phase-Based Progress Estimates

Ceralasertibfor Osteosarcoma

FDA Approved Drug

This trial is being done to see if using these two drugs together can help patients with osteosarcoma who haven't responded to other treatments, or whose cancer has returned after treatment.

FDA Approved Drug

Dana Farber Cancer Institite (+2 Sites)Katherine Janeway, MDAstraZeneca

Image of HonorHealth Research Institute in Scottsdale, United States.

Phase-Based Progress Estimates

CRX100 Suspension For Infusionfor Triple Negative Breast Neoplasms

This trial is testing a new cancer drug to see if it is safe and effective. The drug will be given to patients with different types of cancer to see if it shrinks their tumors.

HonorHealth Research Institute (+2 Sites)Oliver Dorigo, MDBioEclipse Therapeutics

Image of University of Iowa Hospitals and Clinics in Iowa City, United States.

Phase-Based Progress Estimates

Abemaciclibfor Chondrosarcoma

FDA Approved Drug

This trial will enroll 45 subjects with metastatic or unresectable soft tissue sarcoma or bone sarcoma. All subjects will receive Abemaciclib 200 mg twice daily until progression or discontinuation criteria are met.

FDA Approved Drug

University of Iowa Hospitals and Clinics (+3 Sites)John Charlson, MD

Image of Mayo Clinic in Florida in Jacksonville, United States.

Phase-Based Progress Estimates

Glucarpidasefor Osteosarcoma

FDA Approved Drug

This trial is testing how well glucarpidase reduces toxicity in patients with osteosarcoma receiving high doses of methotrexate.

FDA Approved Drug

Mayo Clinic in Florida (+4 Sites)Lara E Davis

Image of Children's Hospital Colorado in Aurora, United States.

Phase-Based Progress Estimates

Losartanfor Osteosarcoma

FDA Approved Drug

This trial is testing a combination of two drugs to see what the highest dose is that people can tolerate without serious side effects. Once they find that, they'll test that dose to see if it's effective.

FDA Approved Drug

Children's Hospital Colorado (+1 Sites)Carrye Cost, MD

Image of Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill in Chapel Hill, United States.

Phase-Based Progress Estimates

IC9.GD2.CAR.IL-15 T-cellsfor Osteosarcoma

FDA Approved Drug

This trial is testing a new cancer treatment that combines two existing ways of fighting disease: antibodies and T cells. Antibodies are molecules that fight infections and protect your body from diseases caused by bacteria and toxic substances. T cells are special infection-fighting blood cells that can kill other cells, including tumor cells or cells that are infected. The new treatment being researched is called autologous T lymphocyte chimeric antigen receptor cells (CAR) cells targeted against the disialoganglioside (GD2) antigen that express Interleukin (IL)-15, and the inducible caspase 9 safety switch (iC9

FDA Approved Drug

Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill (+1 Sites)George Hucks, MDBellicum Pharmaceuticals

Image of Phoenix Children's Hospital in Phoenix, United States.

Phase-Based Progress Estimates

Post Treatment Surgeryfor Osteosarcoma

FDA Approved Drug

This trial is testing a new cancer treatment to see if it is safe and effective for people with a certain type of bone cancer.

FDA Approved Drug

Phoenix Children's Hospital (+24 Sites)Mihaela M Druta, MDBristol-Myers Squibb

Image of Seattle Children's Hospital in Seattle, United States.

Phase-Based Progress Estimates

Second Generation 4-1BBζ EGFR806-EGFRtfor Wilms Tumor

This trial is testing genetically-modified T cells to treat solid tumors in children and young adults. The goal is to evaluate safety and feasibility, and to determine if the cells can kill tumors.

Seattle Children's HospitalKatie Albert, MD

Image of Lucile Packard Children's Hospital in Palo Alto, United States.

Phase-Based Progress Estimates

CLR 131for Neuroblastoma

This trial is testing a new cancer treatment called CLR 131 in children, adolescents, and young adults with cancer that has come back or didn't respond to initial treatment and for which there are no standard treatment options.

Lucile Packard Children's Hospital (+5 Sites)John Friend, MDCellectar Biosciences, Inc.

Image of University of Colorado in Aurora, United States.

Phase-Based Progress Estimates

CAB-AXL-ADCfor Osteosarcoma

This trial is testing a new cancer drug to see if it is safe and effective.

University of Colorado (+27 Sites)BioAtla, Inc.

Image of Sarcoma Oncology Research Center in Santa Monica, United States.

Phase-Based Progress Estimates

CB-103for T-ALL

This trial is testing a new drug, CB-103, to see if it is safe and effective. So far, it seems to be working well.

Sarcoma Oncology Research Center (+2 Sites)Cellestia Biotech AG

Image of Children's Hospital of Alabama in Birmingham, United States.

Phase-Based Progress Estimates

Vemurafenibfor Central Nervous System Neoplasms

Waitlist Available

FDA Approved Drug

This trial studies how well vemurafenib works in treating patients with solid tumors, non-Hodgkin lymphoma, or histiocytic disorders with BRAF V600 mutations.

Waitlist Available

FDA Approved Drug

Children's Hospital of Alabama (+99 Sites)AeRang Kim

Image of Children's Hospital of Alabama in Birmingham, United States.

Phase-Based Progress Estimates

Cabozantinib S-malatefor Osteosarcoma

Waitlist Available

FDA Approved Drug

This study is evaluating whether cabozantinib-s-malate is effective in treating sarcomas, Wilms tumor, or other rare tumors that have come back, do not respond to therapy, or are newly diagnosed.

Waitlist Available

FDA Approved Drug

Children's Hospital of Alabama (+99 Sites)Srivandana Akshintala

Image of St. Jude Children's Research Hospital in Memphis, United States.

Phase-Based Progress Estimates

Diffusion Weighted Magnetic Resonance Imagingfor Rhabdomyosarcoma

Waitlist Available

This trial is testing whether a method that doesn't involve radiation (DW-MRI) can be used instead of current methods (CT, nuclear bone scan, PET-CT) to measure how well children with sarcomas are responding to therapy, in order to reduce exposure to harmful effects of ionizing radiation.

Waitlist Available

St. Jude Children's Research HospitalMary E. McCarville, MD

Image of Arkansas Children's Hospital in Little Rock, United States.

Phase-Based Progress Estimates

Guided Therapyfor Clear Cell Sarcoma of Soft Tissue

Waitlist Available

This trial is testing if new technology that decodes a tumor's DNA can help docs better understand cancer & predict treatment.

Waitlist Available

Arkansas Children's Hospital (+17 Sites)Giselle Sholler, MDDell, Inc.

Image of Children's Hospital of Wisconsin in Milwaukee, United States.

Phase-Based Progress Estimates

Allogeneic HCTfor Neuroblastoma

Waitlist Available

This trial is testing a new treatment for high-risk solid tumors that uses a patient's own cells. It is hoped that this treatment will be more effective than current treatments and have fewer side effects.

Waitlist Available

Children's Hospital of Wisconsin (+1 Sites)Monica Thakar, MD

Image of Cincinnati Children's Hospital Medical Center in Cincinnati, United States.

Phase-Based Progress Estimates

MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Cyclophosphamidefor Osteosarcoma

FDA Approved Drug

This trial is testing a new cancer drug combo to see what the highest safe dose is.

FDA Approved Drug

Cincinnati Children's Hospital Medical Center (+6 Sites)Paul Harker-Murray, MD

Image of St. Jude Children's Research Hospital in Memphis, United States.

Phase-Based Progress Estimates

Methioninefor Neuroblastoma

FDA Approved Drug

This trial is testing the usefulness of imaging with radiolabeled methionine to find tumors in children and young adults.

FDA Approved Drug

St. Jude Children's Research HospitalBarry L Shulkin, MD

Image of Childrens Hospital Orange County in Orange, United States.

Phase-Based Progress Estimates

Surufatinib In Combination With Gemcitabinefor Rhabdomyosarcoma

FDA Approved Drug

This trial is testing the safety of a new cancer drug in children. It will help determine the best dose of the drug to give to children in the future.

FDA Approved Drug

Childrens Hospital Orange County (+10 Sites)Josephine HaduongHutchison Medipharma Limited

25 Osteosarcoma Clinical Trials Near Me

Top Hospitals for Osteosarcoma Clinical Trials

Image of Children's Hospital Los Angeles in California.

Children's Hospital Los Angeles

Los Angeles

24Active Trials

42All Time Trials for Osteosarcoma

1999First Osteosarcoma Trial

Image of Children's Hospital Colorado in Colorado.

Children's Hospital Colorado

Aurora

22Active Trials

33All Time Trials for Osteosarcoma

2005First Osteosarcoma Trial

Top Cities for Osteosarcoma Clinical Trials

Image of Los Angeles in California.

Los Angeles

56Active Trials

Children's Hospital Los AngelesTop Active Site

Image of Saint Louis in Missouri.

Saint Louis

53Active Trials

Washington University School of MedicineTop Active Site

Osteosarcoma Clinical Trials by Phase of Trial

Phase < 1 Osteosarcoma Clinical Trials

4Active Osteosarcoma Clinical Trials

3Number of Unique Treatments

6Number of Active Locations

Glucarpidase SWE Ascorbate Ascorbate

Osteosarcoma Clinical Trials by Age Group

< 18 Osteosarcoma Clinical Trials

1Active Osteosarcoma Clinical Trials