Osteosarcoma Clinical Trials 2024

What are the top hospitals conducting osteosarcoma research?

When it comes to advancing the treatment of osteosarcoma, Children's hospitals across the United States are leading the charge. In Aurora, Colorado, Children's Hospital Colorado is at the forefront with an impressive 23 active clinical trials focused on this bone cancer. Since their first recorded osteosarcoma trial in 2005, they have conducted a total of 34 studies dedicated to improving outcomes for young patients facing this challenging disease.

Meanwhile, in Los Angeles, California, Children's Hospital Los Angeles is also making significant strides in osteosarcoma research. With 22 ongoing trials and a total of 43 completed studies since their pioneering osteosarcoma trial in 1999, this institution has been committed to finding innovative approaches to tackle this aggressive form of cancer.

On the other side of the country in Washington D.C., Children's National Medical Center is actively involved in pushing boundaries against osteosarcoma as well. They currently have 22 ongoing clinical trials and have completed a commendable number of 40 investigations since recording their first study on this condition back in 1999.

In Birmingham, Alabama, children battling osteosarcoma can find hope at the Children's Hospital of Alabama. This hospital boasts an impressive lineup with its involvement in twenty active clinical trials and thirty-five previous projects devoted solely to tackling this challenging cancer subtype since starting their inaugural study on it backin2005.

Lastly but not least important Riley Hospital for Children located Indianapolis has also emerged as a key player with twenty current ongoing tests aided by35 previously held experiments exclusively targetingOsteocarcinoma ; And all these initiated from year2005 marking foundation stones laid towards discovery through various exploration strategies

These esteemed institutions represent beacons of hope for those affected by osteosarcoma and serve as prime examples that collaboration among top pediatric hospitals can lead us closer towards breakthroughs that will transform lives around the world

Which are the best cities for osteosarcoma clinical trials?

In the realm of osteosarcoma clinical trials, several cities emerge as top contenders. New york City leads the way with 65 active trials exploring various treatments like Pharmacological Study, Tazemetostat, and Tipifarnib. Saint Louis, Missouri follows closely behind with 52 ongoing studies investigating interventions such as Pharmacological Study, Vemurafenib, and Dinutuximab. Houston, Texas is another notable hub for research with 49 active trials examining methodologies like Thoracoscopy and MM-398 plus cyclophosphamide. Lastly, Los Angeles, California and Orlando, Florida both exhibit significant activity in osteosarcoma trials with a focus on Pharmalogical Study alongside different therapeutic options including Doxorubicin and Olaparib. These cities provide opportunities to participate in cutting-edge clinical trials that are crucial in advancing our knowledge and treatment approaches towards osteosarcoma.

Which are the top treatments for osteosarcoma being explored in clinical trials?

Osteosarcoma, a challenging bone cancer, is the focus of several cutting-edge treatments currently being explored in clinical trials. Among them are:

• Pharmacological Study: With three active trials and 13 all-time osteosarcoma trials since its introduction in 2010, this treatment option shows promise.
• Nivolumab: Introduced in 2015, nivolumab has shown potential with two active trials and seven all-time osteosarcoma trials to date.
• Abemaciclib: First listed in 2016, abemaciclib is involved in two ongoing clinical trials for osteosarcoma.
• Doxorubicin: A veteran on the scene since 2003, doxorubicin continues to be studied with two active and seven all-time osteosarcoma trials under its belt.
• UB_TT170: Although relatively new (listed only in 2022), UB_TT170 already boasts one active trial dedicated to exploring its potential as an effective treatment for osteosarcoma. As research progresses further, these innovative treatments offer hope for improved outcomes among patients battling this relentless disease.

What are the most recent clinical trials for osteosarcoma?

Recent clinical trials for osteosarcoma offer hope and potential breakthroughs in the treatment of this aggressive bone cancer. Part A of a Phase 1 trial focuses on determining the maximum tolerated dose (MTD) for osteosarcoma, paving the way for more targeted therapies. Another Phase 1 trial explores NPX267 as a potential treatment option, while Cabozantinib undergoes evaluation in a Phase 2 study. Additionally, combination treatments involving chemotherapy and NK cell infusion are being investigated through both Phase 1 and Phase 2 trials. These studies represent significant advancements in our understanding of osteosarcoma therapy and bring us closer to improved outcomes for patients facing this challenging disease.

What osteosarcoma clinical trials were recently completed?

Recent advancements in clinical trials for osteosarcoma offer hope and progress towards improved treatments. In December 2020, the Dana-Farber Cancer Institute completed a trial investigating the potential of Cabozantinib to address this aggressive bone cancer. Additionally, in May 2018, Washington University School of Medicine concluded their study on pegylated arginine deiminase as a potential therapeutic option. Furthermore, St. Jude Children's Research Hospital successfully completed a trial testing Avelumab in February 2017. These recent developments highlight the ongoing efforts to combat osteosarcoma and provide renewed optimism for patients fighting against this devastating disease.