Your session is about to expire
← Back to Search
Vaccine Strain CVD 1208S-122 for Shigellosis
Study Summary
This trial will test a new vaccine for safety and how well it works.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
Find a Location
Logistics
Participation is compensated
You will be compensated for participating in this trial.
Who is running the clinical trial?
Media Library
- I haven't taken any immune-affecting drugs in the last 30 days.You have a history of alcohol or drug abuse in the past 5 years.I have a weakened immune system due to cancer, past cancer treatments, or an immune disorder.I have had diarrhea from traveling to a developing country in the last 3 years.I can stay in the hospital for up to 6 days if needed.I have a history of seizures, but childhood seizures that are resolved are okay.I am generally in good health according to my medical history.I have had abnormal bowel habits, with less than 3 stools per week or more than 2 stools per day in the last 6 months.I have been vaccinated or infected with ETEC, LT, cholera, or Shigella in the last 3 years.I use laxatives, anti-diarrheal, anti-constipation, or antacid medications at least once a week.The investigator believes that any other factors may make it unsafe or difficult for you to participate in the study or may affect the study's results.You have been diagnosed with schizophrenia or another serious mental illness.I am allergic to quinolone or sulpha drugs.I work with food, or care for young children, the elderly, or those with weak immune systems.I have had a cough, shortness of breath, or difficulty breathing not caused by another condition in the last 14 days.I am between 18 and 49 years old.I have not used any form of high-dose steroids in the last 30 days.I haven't had major stomach surgery, except for appendix or gallbladder removal over a year ago.Your body's important signs like heart rate, blood pressure, and temperature are not normal.I am currently breastfeeding.I haven't taken any antibiotics in the last 2 weeks.I have had symptoms like fever, chills, muscle pain, headache, sore throat, or loss of taste/smell recently.I agree to use birth control during and 4 weeks after the trial.I have a long-term stomach or bowel condition like severe indigestion, lactose intolerance, or IBS.
- Group 1: Cohort 1: Shigella Vaccine at 10^8 cfu or Placebo
- Group 2: Cohort 2: Shigella Vaccine at 10^9 cfu or Placebo
- Group 3: Cohort 3: Shigella Vaccine at 10^10 cfu or Placebo
- Group 4: Cohort 4: Shigella Vaccine or Placebo
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What is the scale of participation for this investigation?
"Affirmative. Clinicaltrials.gov reveals that this medical investigation, which was initially posted on September 29th 2022 is still accepting candidates. 54 patients need to be enrolled from one location for the study's completion."
Are there any openings to join this experiment as a participant?
"Affirmative. Clinicaltrials.gov informs us that this experiment, first published on September 29th 2022, is in search of test subjects at the time of writing. A total of 54 participants need to be enrolled from one centre."
Are elderly individuals welcome to participate in this experimental procedure?
"This trial has set the lower and upper age limits at 18 and 49 years old, respectively. Therefore, all participants must be within this range to satisfy eligibility requirements."
Is it possible for me to take part in this clinical experiment?
"This clinical trial is seeking 54 individuals between 18 and 49 years of age with shigella infection. Participants must be in good health as defined by an absence of a chronic medical condition that requires daily prescription medication, although infrequent PRN medications are allowed at the investigator's discretion. Furthermore, any chronic illness which could lead to rapid dehydration would make participants ineligible for this study."
What risks do individuals face when exposed to strain CVD 1208S-122?
"The safety of strain CVD 1208S-122 has been deemed a 1, which reflects the fact that this is only in its first phase clinical trial. This suggests limited data indicating efficacy and safety at present."
Share this study with friends
Copy Link
Messenger