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Treatment for Postoperative Pain

Phase 4

Waitlist Available

Led By Kamell Eckroth-Bernard, MD

Research Sponsored by University of California, San Francisco

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

patients who require major lower extremity amputations

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 months

Awards & highlights

Study Summary

This trial will test whether regional nerve blocks can help with pain control, narcotic use, and length of stay after amputation surgery.

Eligible Conditions

Postoperative Pain

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Postoperative Pain

Trial Design

2Treatment groups

Active Control

Placebo Group

Group I: TreatmentActive Control1 Intervention

Patients randomized to the treatment group will receive regional nerve blocks (sciatic and femoral) with bupivacaine at the dose of 1 mg/kg.

Group II: ControlPlacebo Group1 Intervention

Patients randomized to the control group will receive two needle sticks (in the sciatic and femoral distributions) with normal saline to maintain the double-blinded investigation.

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of California, San FranciscoLead Sponsor

2,503 Previous Clinical Trials

15,236,613 Total Patients Enrolled

6 Trials studying Postoperative Pain

3,381 Patients Enrolled for Postoperative Pain

Kamell Eckroth-Bernard, MDPrincipal InvestigatorUniversity of California, San Francisco

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Has this treatment attained the approval of the Federal Drug Administration?

"With the approval of a Phase 4 trial, there is ample support for this treatment's safety and it was therefore assigned a score of 3."

Answered by AI

Are there any other research initiatives that have assessed the efficacy of this particular remedy?

"Presently, 109 clinical trials for this medicinal intervention are in progress. Of those investigations, 18 have advanced to the third phase of research. The majority of the tests take place in Philadelphia however there are a total of 144 locations running these studies."

Answered by AI

What ailment does this treatment typically address?

"This medication is regularly utilized to treat pemphigus, but can serve as an effective remedy for acute nonspecific tenosynovitis, general anesthesia, and lupus erythematosus cell."

Answered by AI

Are there still vacancies available for this scientific research?

"Information on clinicaltrials.gov affirms that this trial is presently recruiting individuals, having been initially posted on the first day of January in 2018 and recently revised on February 12th 2020."

Answered by AI

How many volunteers have signed up for this clinical experiment?

"Affirmative. Information hosted on clinicaltrials.gov corroborates the fact that this research study, initially posted on January 1st 2018, is seeking out recruits at present. 300 participants from a single medical center are required for the trial's completion."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Peripheral Nerve Blocks for Major Lower Extremity Amputations

2018. "Peripheral Nerve Blocks for Major Lower Extremity Amputations". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03174782.